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Items: 1 to 20 of 23

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou
Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373
PMCID:
PMC9016320
AbstractArticlePDF–3.0M
3.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein
Pankaj Sharma, Elena Maklashina, Gary Cecchini, T. M. Iverson
Proc Natl Acad Sci U S A. 2020 Sep 22; 117(38): 23548–23556. Published online 2020 Sep 4. doi: 10.1073/pnas.2007391117
PMCID:
PMC7519310
AbstractArticlePDF–1.4M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
A Family With a Carotid Body Paraganglioma and Thyroid Neoplasias With a New SDHAF2 Germline Variant
Katherine I Wolf, Michelle F Jacobs, Rohit Mehra, Priya Begani, Matthew S Davenport, Lawrence J Marentette, Gregory J Basura, David T Hughes, Tobias Else
J Endocr Soc. 2019 Nov 1; 3(11): 2151–2157. Published online 2019 Sep 5. doi: 10.1210/js.2018-00353
PMCID:
PMC6821206
AbstractArticlePDF–880K
8.
SDH5 Depletion Enhances Radiosensitivity by Regulating p53: A New Method for Noninvasive Prediction of Radiotherapy Response
Yan Zong, Qianwen Li, Furong Zhang, Xunde Xian, Sihua Wang, Jiahong Xia, Jie Li, Zhan Tuo, Guangqin Xiao, Li Liu, Guiling Li, Sheng Zhang, Gang Wu, Jun Liu
Theranostics. 2019; 9(22): 6380–6395. Published online 2019 Aug 14. doi: 10.7150/thno.34443
PMCID:
PMC6771232
AbstractArticlePDF–3.6M
9.
Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention
Birke Bausch, Francesca Schiavi, Ying Ni, Jenny Welander, Attila Patocs, Joanne Ngeow, Ulrich Wellner, Angelica Malinoc, Elisa Taschin, Giovanni Barbon, Virginia Lanza, Peter Söderkvist, Adam Stenman, Catharina Larsson, Fredrika Svahn, Jin-Lian Chen, Jessica Marquard, Merav Fraenkel, Martin A. Walter, Mariola Peczkowska, Aleksander Prejbisz, Barbara Jarzab, Kornelia Hasse-Lazar, Stephan Petersenn, Lars C. Moeller, Almuth Meyer, Nicole Reisch, Arnold Trupka, Christoph Brase, Matthias Galiano, Simon F. Preuss, Pingling Kwok, Nikoletta Lendvai, Gani Berisha, Özer Makay, Carsten C. Boedeker, Georges Weryha, Karoly Racz, Andrzej Januszewicz, Martin K. Walz, Oliver Gimm, Giuseppe Opocher, Charis Eng, Hartmut P. H. Neumann
JAMA Oncol. 2017 Sep; 3(9): 1204–1212. Published online 2017 Apr 6. doi: 10.1001/jamaoncol.2017.0223
PMCID:
PMC5824290
AbstractArticle
10.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas
Attje S. Hoekstra, Erik F. Hensen, Ekaterina S. Jordanova, Esther Korpershoek, van der Horst-Schrivers Anouk N.A., Cees Cornelisse, Eleonora P.M. Corssmit, Frederik J. Hes, Jeroen C. Jansen, Henricus P.M. Kunst, Henri J.L.M. Timmers, Adrian Bateman, Diana Eccles, Judith V.M.G. Bovée, Peter Devilee, Jean-Pierre Bayley
Oncotarget. 2017 Feb 28; 8(9): 14525–14536. Published online 2017 Jan 14. doi: 10.18632/oncotarget.14649
PMCID:
PMC5362423
AbstractArticlePDF–9.8M
13.
The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells
Ayenachew Bezawork-Geleta, Lanfeng Dong, Jakub Rohlena, Jiri Neuzil
J Biol Chem. 2016 Oct 7; 291(41): 21414–21420. Published online 2016 Sep 1. doi: 10.1074/jbc.C116.755017
PMCID:
PMC5076811
AbstractArticlePDF–1007K
14.
Hereditary Paragangliomas
Margarita Raygada, Barbara Pasini, Constantine A. Stratakis
Adv Otorhinolaryngol. Author manuscript; available in PMC 2014 Nov 5.
Published in final edited form as: Adv Otorhinolaryngol. 2011; 70: 99–106. Published online 2011 Feb 24. doi: 10.1159/000322484
PMCID:
PMC4221053
AbstractArticlePDF–171K
15.
SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
Huai-Xiang Hao, Oleh Khalimonchuk, Margit Schraders, Noah Dephoure, Jean-Pierre Bayley, Henricus Kunst, Peter Devilee, Cor W. R. J. Cremers, Joshua D. Schiffman, Brandon G. Bentz, Steven P. Gygi, Dennis R. Winge, Hannie Kremer, Jared Rutter
Science. Author manuscript; available in PMC 2014 Jan 6.
Published in final edited form as: Science. 2009 Aug 28; 325(5944): 10.1126/science.1175689. Published online 2009 Jul 23. doi: 10.1126/science.1175689
PMCID:
PMC3881419
AbstractArticlePDF–2.0M
16.
Succinate Dehydrogenase 5 (SDH5) Regulates Glycogen Synthase Kinase 3β-β-Catenin-mediated Lung Cancer Metastasis
Jun Liu, Liuwei Gao, Hua Zhang, Daowei Wang, Meng Wang, Jianquan Zhu, Cong Pang, Changli Wang
J Biol Chem. 2013 Oct 11; 288(41): 29965–29973. Published online 2013 Aug 27. doi: 10.1074/jbc.M113.450106
PMCID:
PMC3795294
AbstractArticlePDF–2.4M
17.
ACMG Recommendations for Reporting of Incidental Findings in Clinical Exome and Genome Sequencing
Robert C. Green, Jonathan S. Berg, Wayne W. Grody, Sarah S. Kalia, Bruce R. Korf, Christa L. Martin, Amy McGuire, Robert L. Nussbaum, Julianne M. O’Daniel, Kelly E. Ormond, Heidi L. Rehm, Michael S. Watson, Marc S. Williams, Leslie G. Biesecker
Genet Med. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Genet Med. 2013 Jul; 15(7): 565–574. Published online 2013 Jun 20. doi: 10.1038/gim.2013.73
PMCID:
PMC3727274
AbstractArticlePDF–65K
18.
Emerging Concepts in the Flavinylation of Succinate Dehydrogenase
Hyung J. Kim, Dennis R. Winge
Biochim Biophys Acta. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Biochim Biophys Acta. 2013 May; 1827(5): 627–636. Published online 2013 Feb 1. doi: 10.1016/j.bbabio.2013.01.012
PMCID:
PMC3626088
AbstractArticlePDF–1.4M
19.
A Census of Human Soluble Protein Complexes
Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili
Cell. Author manuscript; available in PMC 2013 Aug 31.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011
PMCID:
PMC3477804
AbstractArticlePDF–7.7M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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