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Select item 99714611.

The Effect of Caspase 8, 9 Gene Polymorphisms on Non-Hodgkin Lymphoma Susceptibility and Clinical/Pathological Features

Fatemeh Barati, Gholamreza Bahari, Anoosha Asadi, Alireza Nakhaee, Seyed-Mehdi Hashemi, Mohsen Taheri, Mohammad Hashemi

Asian Pac J Cancer Prev. 2022 Dec; 23(12): 4339–4346. doi: 10.31557/APJCP.2022.23.12.4339

PMCID:: PMC9971461

Abstract Article PDF–454K

Select item 99224682.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 93569803.

Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

Minjung Kim, Ngoc T. Vu, Xue Wang, Gamze B. Bulut, Min-Hsuan Wang, Cora Uram-Tuculescu, Raghavendra Pillappa, Sungjune Kim, Charles E. Chalfant

Mol Cancer Res. 2022 Aug 5; 20(8): 1284–1294. Published online 2022 Apr 12. doi: 10.1158/1541-7786.MCR-21-0905

PMCID:: PMC9356980

Abstract Article PDF–1.9M

Select item 92392664.

Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases

Yaxin Liu, Huan Zeng, Yanjie Hou, Zilin Li, Lin Li, Xiaocui Song, Jingjin Ding, Feng Shao, Yue Xu

mBio. 2022 May-Jun; 13(3): e00690-22. Published online 2022 Apr 21. doi: 10.1128/mbio.00690-22

PMCID:: PMC9239266

Abstract Article PDF–3.2M

Select item 88064425.

lncRNA PROX1-AS1 mediates the migration and invasion of placental trophoblast cells via the miR-211-5p/caspase-9 axis

Dan Tang, Li Geng, Jing Ma

Bioengineered. 2021; 12(1): 4100–4110. Published online 2021 Jul 21. doi: 10.1080/21655979.2021.1953213

PMCID:: PMC8806442

Abstract Article PDF–2.2M

Select item 83866086.

CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis

Hyun-Kyu An, Kyung Min Chung, Hyunhee Park, Jihyun Hong, Ji-Eun Gim, Hyosun Choi, Ye Won Lee, Jieun Choi, Ji Young Mun, Seong-Woon Yu

Autophagy. 2020; 16(9): 1598–1617. Published online 2019 Dec 10. doi: 10.1080/15548627.2019.1695398

PMCID:: PMC8386608

Abstract Article PDF–25M

Select item 82049627.

Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR endosomal transport

Jie Han, Leslie A. Goldstein, Wen Hou, Simon C. Watkins, Hannah Rabinowich

Autophagy. 2021; 17(6): 1393–1409. Published online 2020 May 25. doi: 10.1080/15548627.2020.1761742

PMCID:: PMC8204962

Abstract Article PDF–18M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80286189.

CASP9 germline mutation in a family with multiple brain tumors

Michael W. Ronellenfitsch, Ji‐Eun Oh, Kaishi Satomi, Koichiro Sumi, Patrick N. Harter, Joachim P. Steinbach, Jörg Felsberg, David Capper, Catherine Voegele, Geoffroy Durand, James McKay, Florence Le Calvez‐Kelm, Jens Schittenhelm, Barbara Klink, Michel Mittelbronn, Hiroko Ohgaki

Brain Pathol. 2018 Jan; 28(1): 94–102. Published online 2017 Apr 17. doi: 10.1111/bpa.12471

PMCID:: PMC8028618

Abstract Article PDF–1.1M

Select item 801772010.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 717773911.

Upregulation of CASP9 through NF-κB and Its Target MiR-1276 Contributed to TNFα-Promoted Apoptosis of Cancer Cells Induced by Doxorubicin

Fei Zhou, Yun Li, Yisheng Huang, Jian Wu, Qinhan Wu, Hui Zhu, Jinke Wang

Int J Mol Sci. 2020 Apr; 21(7): 2290. Published online 2020 Mar 26. doi: 10.3390/ijms21072290

PMCID:: PMC7177739

Abstract Article PDF–5.0M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 714530113.

Major Contribution of Caspase-9 to Honokiol-Induced Apoptotic Insults to Human Drug-Resistant Glioblastoma Cells

Gong-Jhe Wu, Sun-Ta Yang, Ruei-Ming Chen

Molecules. 2020 Mar; 25(6): 1450. Published online 2020 Mar 23. doi: 10.3390/molecules25061450

PMCID:: PMC7145301

Abstract Article PDF–2.8M

Select item 698120614.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 674264615.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 671572516.

Maximizing binary interactome mapping with a minimal number of assays

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Luke Lambourne, Kerstin Spirohn, Irma Lemmens, Mélanie Dos Santos, Caroline Demeret, Louis Jones, Sudharshan Rangarajan, Wenting Bian, Eloi P. Coutant, Yves L. Janin, Sylvie van der Werf, Philipp Trepte, Erich E. Wanker, Javier De Las Rivas, Jan Tavernier, Jean-Claude Twizere, Tong Hao, David E. Hill, Marc Vidal, Michael A. Calderwood, Yves Jacob

Nat Commun. 2019; 10: 3907. Published online 2019 Aug 29. doi: 10.1038/s41467-019-11809-2

PMCID:: PMC6715725

Abstract Article PDF–1.7M

Select item 667240917.

HIV-1 Vpr Causes Neuronal Apoptosis and In Vivo Neurodegeneration

Gareth J. Jones, Nicola L. Barsby, Éric A. Cohen, Janet Holden, Kim Harris, Peter Dickie, Jack Jhamandas, Christopher Power

J Neurosci. 2007 Apr 4; 27(14): 3703–3711. doi: 10.1523/JNEUROSCI.5522-06.2007

PMCID:: PMC6672409

Abstract Article PDF–521K

Select item 666591218.

Caspase-9 Activation Revealed by Semaphorin 7A Cleavage Is Independent of Apoptosis in the Aged Olfactory Bulb

Shizue Ohsawa, Shun Hamada, Hiroaki Asou, Keiuke Kuida, Yasuo Uchiyama, Hiroki Yoshida, Masayuki Miura

J Neurosci. 2009 Sep 9; 29(36): 11385–11392. doi: 10.1523/JNEUROSCI.4780-08.2009

PMCID:: PMC6665912

Abstract Article PDF–2.4M

Select item 664553519.

Cullin-4B E3 ubiquitin ligase mediates Apaf-1 ubiquitination to regulate caspase-9 activity

Eri Ohta, Masanori Itoh, Masashi Ueda, Yoko Hida, Miao-xing Wang, Miki Hayakawa-Ogura, Shimo Li, Emika Nishida, Kazunori Ohta, Tana, Saiful Islam, Kiyomi Nakagawa, Tomomi Sunayama, Huayue Chen, So Hirata, Masashi Endo, Yoya Ohno, Toshiyuki Nakagawa

PLoS One. 2019; 14(7): e0219782. Published online 2019 Jul 22. doi: 10.1371/journal.pone.0219782

PMCID:: PMC6645535

Abstract Article PDF–2.9M

Select item 648996420.

Genetic screening and functional analysis of CASP9 mutations in a Chinese cohort with neural tube defects

Xiao‐Zhen Liu, Qin Zhang, Qian Jiang, Bao‐Ling Bai, Xiao‐Juan Du, Fang Wang, Li‐Hua Wu, Xiao‐Lin Lu, Yi‐Hua Bao, Hui‐Li Li, Ting Zhang

CNS Neurosci Ther. 2018 May; 24(5): 394–403. Published online 2018 Jan 24. doi: 10.1111/cns.12797

PMCID:: PMC6489964

Abstract Article PDF–1.3M

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