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Select item 104540201.

TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway

Weiqi Xu, Lihong Zhuang, Hongxu Zhu, Anrong Mao, Jiamin Zhou, Lu Wang

Int J Mol Sci. 2023 Aug; 24(16): 12589. Published online 2023 Aug 9. doi: 10.3390/ijms241612589

PMCID:: PMC10454020

Abstract Article PDF–6.1M

Select item 100339372.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 99504473.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 97725584.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 89737596.

Circular RNA circ_0048764 promotes the development of breast cancer by regulating microRNA-1296-5p/tripartite motif containing 14 axis

Fei Xie, Yuyuan Xiong, Jiayin Yan, Ling Wang, Wei Yan

Bioengineered. 2022; 13(2): 1963–1974. Published online 2022 Jan 16. doi: 10.1080/21655979.2021.1995990

PMCID:: PMC8973759

Abstract Article PDF–1.8M

Select item 88515367.

TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation

Di Liu, Zhiyao Zhao, Yuanchu She, Lei Zhang, Xiangtian Chen, Ling Ma, Jun Cui

Proc Natl Acad Sci U S A. 2022 Feb 15; 119(7): e2113454119. Published online 2022 Feb 10. doi: 10.1073/pnas.2113454119

PMCID:: PMC8851536

Abstract Article PDF–1.7M

Select item 85202628.

Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway

Hui Cheng, Jie Ding, Gusheng Tang, Aijie Huang, Lei Gao, Jianmin Yang, Li Chen

Mol Med. 2021; 27: 128. Published online 2021 Oct 16. doi: 10.1186/s10020-021-00393-1

PMCID:: PMC8520262

Abstract Article PDF–3.3M

Select item 81836769.

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

Kazuki Kato, Sadeem Ahmad, Zixiang Zhu, Janet M. Young, Xin Mu, Sehoon Park, Harmit S. Malik, Sun Hur

Mol Cell. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Mol Cell. 2021 Feb 4; 81(3): 599–613.e8. Published online 2020 Dec 28. doi: 10.1016/j.molcel.2020.11.047

PMCID:: PMC8183676

Abstract Article PDF–3.6M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814849411.

TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways

Jiangyan Chen, Lin Huang, Jin Quan, Debing Xiang

Aging (Albany NY) 2021 May 15; 13(9): 13225–13238. Published online 2021 May 11. doi: 10.18632/aging.203003

PMCID:: PMC8148494

Abstract Article PDF–2.2M

Select item 784841712.

TRIM14 Promotes Breast Cancer Cell Proliferation by Inhibiting Apoptosis

Gaowu Hu, Wei Pen, Ming Wang

Oncol Res. 2019; 27(4): 439–447. Published online 2019 Mar 29. doi: 10.3727/096504018X15214994641786

PMCID:: PMC7848417

Abstract Article PDF–3.8M

Select item 718171813.

TRIM14 promotes endothelial activation via activating NF-κB signaling pathway

Xuan Huang, Yong Li, Xiuzhen Li, Daping Fan, Hong-Bo Xin, Mingui Fu

J Mol Cell Biol. 2020 Mar; 12(3): 176–189. Published online 2019 May 9. doi: 10.1093/jmcb/mjz040

PMCID:: PMC7181718

Abstract Article PDF–1.5M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x