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Select item 100741061.

The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential

Kenji F Shoji, Elsa Bayet, Sabrina Leverrier‐Penna, Dahiana Le Devedec, Aude Mallavialle, Séverine Marionneau‐Lambot, Florian Rambow, Raul Perret, Aurélie Joussaume, Roselyne Viel, Alain Fautrel, Amir Khammari, Bruno Constantin, Sophie Tartare‐Deckert, Aubin Penna

EMBO Rep. 2023 Apr; 24(4): e55069. Published online 2023 Feb 6. doi: 10.15252/embr.202255069

PMCID:: PMC10074106

Abstract Article PDF–7.1M

Select item 99885312.

Hypo-osmolarity induces apoptosis resistance via TRPV2-mediated AKT-Bcl-2 pathway

Hayato Urushima, Tsutomu Matsubara, Masaaki Miyakoshi, Shioko Kimura, Hideto Yuasa, Katsutoshi Yoshizato, Kazuo Ikeda

Am J Physiol Gastrointest Liver Physiol. 2023 Mar 1; 324(3): G219–G230. Published online 2023 Jan 31. doi: 10.1152/ajpgi.00138.2022

PMCID:: PMC9988531

Abstract Article

Select item 99171683.

Impact of the TRPV2 Inhibitor on Advanced Heart Failure in Patients with Muscular Dystrophy: Exploratory Study of Biomarkers Related to the Efficacy of Tranilast

Chisato Takahashi, Mariko Oishi, Yuko Iwata, Keiko Maekawa, Tsuyoshi Matsumura

Int J Mol Sci. 2023 Feb; 24(3): 2167. Published online 2023 Jan 21. doi: 10.3390/ijms24032167

PMCID:: PMC9917168

Abstract Article PDF–990K

Select item 97460994.

Predictive value of TRPV2 expression from peripheral blood mononuclear cells on the early recurrence of atrial fibrillation after radiofrequency catheter ablation

Xuebin Ling, Jun Wang, Xue Qin, Chufen Lin, Wei Jie, Yane Chen, Dajia Fu, Yang Yang, Qingwen Meng, Jing Lin, Hui Liu, Tianfa Li, Junli Guo

BMC Cardiovasc Disord. 2022; 22: 546. Published online 2022 Dec 13. doi: 10.1186/s12872-022-02992-0

PMCID:: PMC9746099

Abstract Article PDF–1.7M

Select item 97229165.

Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

Liying Zhang, Charlotte Simonsen, Lucie Zimova, Kaituo Wang, Lavanya Moparthi, Rachelle Gaudet, Maria Ekoff, Gunnar Nilsson, Ute A. Hellmich, Viktorie Vlachova, Pontus Gourdon, Peter M. Zygmunt

Nat Commun. 2022; 13: 7483. Published online 2022 Dec 5. doi: 10.1038/s41467-022-35163-y

PMCID:: PMC9722916

Abstract Article PDF–35M

Select item 95539076.

Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma

Rongqi Huang, Shuai Li, Chao Tian, Peng Zhou, Huifang Zhao, Wei Xie, Jie Xiao, Ling Wang, Jean de Dieu Habimana, Zuoxian Lin, Yuchen Yang, Na Cheng, Zhiyuan Li

Br J Cancer. 2022 Nov 1; 127(8): 1424–1439. Published online 2022 Jul 27. doi: 10.1038/s41416-022-01896-2

PMCID:: PMC9553907

Abstract Article PDF–4.4M

Select item 95100997.

Extent of intrinsic disorder and NMR chemical shift assignments of the distal N-termini from human TRPV1, TRPV2 and TRPV3 ion channels

Christoph Wiedemann, Benedikt Goretzki, Zoe N. Merz, Frederike Tebbe, Pauline Schmitt, Ute A. Hellmich

Biomol NMR Assign. 2022; 16(2): 289–296. Published online 2022 Jun 6. doi: 10.1007/s12104-022-10093-4

PMCID:: PMC9510099

Abstract Article PDF–1.3M

Select item 92543788.

ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2

Ming-Chuang Sun, Kang Fang, Zhao-Xing Li, Yuan Chu, Ai-Ping Xu, Zi-Ying Zhao, Zhu-Yun Leng, Yun-Wei Zhang, Ze-Hua Zhang, Li Zhang, Tao Chen, Mei-Dong Xu

Int J Med Sci. 2022; 19(6): 1072–1081. Published online 2022 Jun 21. doi: 10.7150/ijms.71892

PMCID:: PMC9254378

Abstract Article PDF–1.9M

Select item 89980659.

Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Linghui Chen, Yanzhuo Chen, Wen Ding, Tao Zhan, Jie Zhu, Lesha Zhang, Han Wang, Bing Shen, Yong Wang

Cells. 2022 Apr; 11(7): 1196. Published online 2022 Apr 2. doi: 10.3390/cells11071196

PMCID:: PMC8998065

Abstract Article PDF–4.0M

Select item 821059510.

TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions

Jinrui Xu, Yuquan Yang, Zhaoyuan Hou, Hao Jia, Yujiong Wang

Theranostics. 2021; 11(15): 7379–7390. Published online 2021 May 25. doi: 10.7150/thno.58781

PMCID:: PMC8210595

Abstract Article PDF–3.2M

Select item 790504011.

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer

Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li

Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502

PMCID:: PMC7905040

Abstract Article PDF–3.2M

Select item 756052312.

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton

Manoj Yadav, Chandan Goswami

Biosci Rep. 2020 Oct 30; 40(10): BSR20200118. Published online 2020 Oct 14. doi: 10.1042/BSR20200118

PMCID:: PMC7560523

Abstract Article PDF–3.5M

Select item 743256513.

The Effects of Cannabidiol and Prognostic Role of TRPV2 in Human Endometrial Cancer

Oliviero Marinelli, Maria Beatrice Morelli, Daniela Annibali, Cristina Aguzzi, Laura Zeppa, Sandra Tuyaerts, Consuelo Amantini, Frédéric Amant, Benedetta Ferretti, Federica Maggi, Giorgio Santoni, Massimo Nabissi

Int J Mol Sci. 2020 Aug; 21(15): 5409. Published online 2020 Jul 29. doi: 10.3390/ijms21155409

PMCID:: PMC7432565

Abstract Article PDF–7.0M

Select item 732206714.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 699554715.

Trafficking of Stretch-Regulated TRPV2 and TRPV4 Channels Inferred Through Interactomics

Pau Doñate-Macián, Jennifer Enrich-Bengoa, Irene R. Dégano, David G. Quintana, Alex Perálvarez-Marín

Biomolecules. 2019 Dec; 9(12): 791. Published online 2019 Nov 27. doi: 10.3390/biom9120791

PMCID:: PMC6995547

Abstract Article PDF–2.9M

Select item 688383116.

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2

Tabea C. Fricke, Frank Echtermeyer, Johannes Zielke, Jeanne de la Roche, Milos R. Filipovic, Stéphane Claverol, Christine Herzog, Makoto Tominaga, Ruth A. Pumroy, Vera Y. Moiseenkova-Bell, Peter M. Zygmunt, Andreas Leffler, Mirjam J. Eberhardt

Proc Natl Acad Sci U S A. 2019 Nov 26; 116(48): 24359–24365. Published online 2019 Nov 12. doi: 10.1073/pnas.1904332116

PMCID:: PMC6883831

Abstract Article PDF–1.3M

Select item 683168117.

The expression and role of TRPV2 in esophageal squamous cell carcinoma

Michihiro Kudou, Atsushi Shiozaki, Yuzo Yamazato, Keita Katsurahara, Toshiyuki Kosuga, Katsutoshi Shoda, Tomohiro Arita, Hirotaka Konishi, Shuhei Komatsu, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Eiichi Konishi, Yoshinori Marunaka, Eigo Otsuji

Sci Rep. 2019; 9: 16055. Published online 2019 Nov 5. doi: 10.1038/s41598-019-52227-0

PMCID:: PMC6831681

Abstract Article PDF–9.5M

Select item 679415818.

LZTR1 is a regulator of RAS ubiquitination and signaling

Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga

Science. Author manuscript; available in PMC 2019 Oct 15.

Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210

PMCID:: PMC6794158

Abstract Article PDF–1.9M

Select item 619189319.

TRPV2-induced Ca²⁺-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma

Hua Bai, Huayuan Zhu, Qing Yan, Xuxing Shen, Xiupan Lu, Juejin Wang, Jianyong Li, Lijuan Chen

Cell Commun Signal. 2018; 16: 68. Published online 2018 Oct 16. doi: 10.1186/s12964-018-0280-8

PMCID:: PMC6191893

Abstract Article PDF–5.7M

Select item 616540420.

Ca²⁺ Signaling and IL-8 Secretion in Human Testicular Peritubular Cells Involve the Cation Channel TRPV2

Katja Eubler, Carola Herrmann, Astrid Tiefenbacher, Frank-Michael Köhn, J. Ullrich Schwarzer, Lars Kunz, Artur Mayerhofer

Int J Mol Sci. 2018 Sep; 19(9): 2829. Published online 2018 Sep 19. doi: 10.3390/ijms19092829

PMCID:: PMC6165404

Abstract Article PDF–6.2M

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