PMC Links for GEO Profiles (Select 132650927) - PMC

Links from GEO Profiles

Items: 1 to 20 of 76

<< First< Prev

Page of 4

Select item 108914441.

Low nuclear expression of HIF‐hydroxylases PHD2/EGLN1 and PHD3/EGLN3 are associated with poor recurrence‐free survival in clear cell renal cell carcinoma

Lassi Luomala, Kalle Mattila, Paula Vainio, Harry Nisén, Teijo Pellinen, Jouni Lohi, Teemu D. Laajala, Petrus Järvinen, Anna‐Riina Koskenniemi, Panu Jaakkola, Tuomas Mirtti

Cancer Med. 2024 Feb; 13(3): e6998. Published online 2024 Feb 24. doi: 10.1002/cam4.6998

PMCID:: PMC10891444

Abstract Article PDF–1.9M

Select item 100339372.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 89332803.

Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growth

Ying Jin, Yamu Pan, Shuang Zheng, Yao Liu, Jie Xu, Yazhi Peng, Zemei Zhang, Yadong Wang, Yulian Xiong, Lei Xu, Kaiyu Mu, Suwen Chen, Fei Zheng, Ye Yuan, Jian Fu

Oncogene. 2022; 41(12): 1752–1766. Published online 2022 Feb 5. doi: 10.1038/s41388-022-02203-2

PMCID:: PMC8933280

Abstract Article PDF–8.6M

Select item 88421654.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 81910295.

USP9X promotes apoptosis in cholangiocarcinoma by modulation expression of KIF1Bβ via deubiquitinating EGLN3

Weiqian Chen, Jingjing Song, Siyu Liu, Bufu Tang, Lin Shen, Jinyu Zhu, Shiji Fang, Fazong Wu, Liyun Zheng, Rongfang Qiu, Chunmiao Chen, Yang Gao, Jianfei Tu, Zhongwei Zhao, Jiansong Ji

J Biomed Sci. 2021; 28: 44. Published online 2021 Jun 10. doi: 10.1186/s12929-021-00738-2

PMCID:: PMC8191029

Abstract Article PDF–2.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80652557.

PHD3 loss promotes exercise capacity and fat oxidation in skeletal muscle

Haejin Yoon, Jessica B. Spinelli, Elma Zaganjor, Samantha J. Wong, Natalie J. German, Elizabeth C. Randall, Afsah Dean, Allen Clermont, Joao A. Paulo, Daniel Garcia, Hao Li, Olivia Rombold, Nathalie Y. R. Agar, Laurie J. Goodyear, Reuben J. Shaw, Steven P. Gygi, Johan Auwerx, Marcia C. Haigis

Cell Metab. Author manuscript; available in PMC 2021 Apr 24.

Published in final edited form as: Cell Metab. 2020 Aug 4; 32(2): 215–228.e7. Published online 2020 Jul 13. doi: 10.1016/j.cmet.2020.06.017

PMCID:: PMC8065255

Abstract Article PDF–1.3M

Select item 80012118.

Prolyl Hydroxylase 3 Knockdown Accelerates VHL-Mutant Kidney Cancer Growth In Vivo

Niki M. Zacharias, Lei Wang, Tapati Maity, Li Li, Steven W. Millward, Jose A. Karam, Christopher G. Wood, Neema Navai

Int J Mol Sci. 2021 Mar; 22(6): 2849. Published online 2021 Mar 11. doi: 10.3390/ijms22062849

PMCID:: PMC8001211

Abstract Article PDF–3.2M

Select item 79610949.

Development of a colorimetric α-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins

Samantha J. Wong, Alison E. Ringel, William Yuan, Joao A. Paulo, Haejin Yoon, Mark A. Currie, Marcia C. Haigis

J Biol Chem. 2021 Jan-Jun; 296: 100397. Published online 2021 Feb 8. doi: 10.1016/j.jbc.2021.100397

PMCID:: PMC7961094

Abstract Article PDF–1.4M

Select item 770531010.

TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation

Sijia Fan, Jing Wang, Guangqing Yu, Fangjing Rong, Dawei Zhang, Chenxi Xu, Juan Du, Zhi Li, Gang Ouyang, Wuhan Xiao

J Biol Chem. 2020 Nov 27; 295(48): 16299–16313. Published online 2020 Sep 22. doi: 10.1074/jbc.RA120.014538

PMCID:: PMC7705310

Abstract Article PDF–2.8M

Select item 741500611.

Label-free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2

Ang Luo, Yue Chen

J Proteome Res. Author manuscript; available in PMC 2020 Aug 9.

Published in final edited form as: J Proteome Res. 2020 Jan 3; 19(1): 260–268. Published online 2019 Dec 6. doi: 10.1021/acs.jproteome.9b00513

PMCID:: PMC7415006

Abstract Article PDF–1.2M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 708413713.

Abrogation of esophageal carcinoma development in miR-31 knockout rats

Louise Y. Fong, Cristian Taccioli, Alexey Palamarchuk, Guidantonio Malagoli Tagliazucchi, Ruiyan Jing, Karl J. Smalley, Sili Fan, Joseph Altemus, Oliver Fiehn, Kay Huebner, John L. Farber, Carlo M. Croce

Proc Natl Acad Sci U S A. 2020 Mar 17; 117(11): 6075–6085. Published online 2020 Mar 2. doi: 10.1073/pnas.1920333117

PMCID:: PMC7084137

Abstract Article PDF–2.7M

Select item 688159114.

Whole-Genome Sequencing Identifies the Egl Nine Homologue 3 (egln3/phd3) and Protein Phosphatase 1 Regulatory Inhibitor Subunit 2 (PPP1R2P1) Associated with High-Altitude Polycythemia in Tibetans at High Altitude

Luobu Gesang, Lamu Gusang, Ciren Dawa, Gawa Gesang, Kang Li

Dis Markers. 2019; 2019: 5946461. Published online 2019 Nov 7. doi: 10.1155/2019/5946461

PMCID:: PMC6881591

Abstract Article PDF–446K

Select item 674264615.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 673986616.

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

Matthew E Cockman, Kerstin Lippl, Ya-Min Tian, Hamish B Pegg, William D Figg, Jnr, Martine I Abboud, Raphael Heilig, Roman Fischer, Johanna Myllyharju, Christopher J Schofield, Peter J Ratcliffe

eLife. 2019; 8: e46490. Published online 2019 Sep 10. doi: 10.7554/eLife.46490

PMCID:: PMC6739866

Abstract Article PDF–4.0M

Select item 673107417.

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation

Luke Erber, Ang Luo, Yue Chen

Mol Cell Proteomics. 2019 Sep; 18(9): 1772–1781. Published online 2019 Jun 25. doi: 10.1074/mcp.RA119.001535

PMCID:: PMC6731074

Abstract Article PDF–1.4M

Select item 671347518.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman

eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362

PMCID:: PMC6713475

Abstract Article PDF–4.6M

Select item 659782519.

Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53–MDM2 interaction in a hydroxylase-independent manner

Yiming Xu, Qiang Gao, Yaqian Xue, Xiuxiu Li, Liang Xu, Chenwei Li, Yanqing Qin, Jing Fang

J Biol Chem. 2019 Jun 21; 294(25): 9949–9958. Published online 2019 May 15. doi: 10.1074/jbc.RA118.007181

PMCID:: PMC6597825

Abstract Article PDF–2.5M

Select item 656550620.

MicroRNA-1205, encoded on chromosome 8q24, targets EGLN3 to induce cell growth and contributes to risk of castration-resistant prostate cancer

Yicun Wang, Xin Li, Wei Liu, Bingjin Li, Dongquan Chen, Fengping Hu, Lizhong Wang, Xiaoguang M. Liu, Ranji Cui, Runhua Liu

Oncogene. Author manuscript; available in PMC 2019 Aug 26.

Published in final edited form as: Oncogene. 2019 Jun; 38(24): 4820–4834. Published online 2019 Feb 26. doi: 10.1038/s41388-019-0760-3

PMCID:: PMC6565506

Abstract Article PDF–2.6M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 76

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity