PMC Links for GEO Profiles (Select 132662998) - PMC

Select item 108373601.

Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis

Dan Nie, Xin Tang, Haijun Deng, Xiaojun Yang, Junji Tao, Fengli Xu, Yi Liu, Kang Wu, Kai Wang, Zhechuan Mei, Ailong Huang, Ni Tang

Adv Sci (Weinh) 2024 Feb; 11(5): 2305374. Published online 2023 Dec 7. doi: 10.1002/advs.202305374

PMCID:: PMC10837360

Abstract Article PDF–12M

Select item 107871012.

Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid

Kang Wu, Yi Liu, Jie Xia, Jiale Liu, Kai Wang, Huijun Liang, Fengli Xu, Dina Liu, Dan Nie, Xin Tang, Ailong Huang, Chang Chen, Ni Tang

Adv Sci (Weinh) 2024 Jan; 11(2): 2304408. Published online 2023 Nov 13. doi: 10.1002/advs.202304408

PMCID:: PMC10787101

Abstract Article PDF–7.4M

Select item 107814983.

Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis

Xiaoyan Li, Jinping Wang, Zongliang Guo, Yong Ma, Dawei Xu, Daguang Fan, Peng Dai, Yifan Chen, Qiongwen Liu, Jinke Jiao, Jinhan Fan, Ningxue Wu, Xin Li, Guoyin Li

Aging (Albany NY) 2023 Dec 31; 15(24): 15084–15113. Published online 2023 Dec 28. doi: 10.18632/aging.205334

PMCID:: PMC10781498

Abstract Article PDF–4.3M

Select item 98371394.

SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase

Feng-li Xu, Xiao-hong Wu, Chang Chen, Kai Wang, Lu-yi Huang, Jie Xia, Yi Liu, Xue-feng Shan, Ni Tang

Cell Death Dis. 2023 Jan; 14(1): 22. Published online 2023 Jan 12. doi: 10.1038/s41419-023-05558-w

PMCID:: PMC9837139

Abstract Article PDF–6.7M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72060866.

SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC

Qingzhu Gao, Guiji Zhang, Yaqiu Zheng, Yi Yang, Chang Chen, Jie Xia, Li Liang, Chong Lei, Yuan Hu, Xuefei Cai, Wenlu Zhang, Hua Tang, Yaxi Chen, Ailong Huang, Kai Wang, Ni Tang

Cell Death Differ. 2020 Mar; 27(3): 1086–1104. Published online 2019 Jul 31. doi: 10.1038/s41418-019-0399-1

PMCID:: PMC7206086

Abstract Article PDF–7.4M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 41753978.

GENETIC DEFECTS IN BILE ACID CONJUGATION CAUSE FAT-SOLUBLE VITAMIN DEFICIENCY

Kenneth D. R. Setchell, James E. Heubi, Sohela Shah, Joel E. Lavine, David Suskind, Mohammed Al-Edreesi, Carol Potter, David W. Russell, Nancy C. O'Connell, Brian Wolfe, Pinky Jha, Wujuan Zhang, Kevin E. Bove, Alex S. Knisely, Alan F. Hofmann, Philip Rosenthal, Laura N. Bull

Gastroenterology. Author manuscript; available in PMC 2014 Sep 25.

Published in final edited form as: Gastroenterology. 2013 May; 144(5): 945–e15. Published online 2013 Feb 13. doi: 10.1053/j.gastro.2013.02.004