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Items: 1 to 20 of 33

1.
FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis
Ganesh Kumar Barik, Osheen Sahay, Anindya Mukhopadhyay, Rajesh Kumar Manne, Sehbanul Islam, Anup Roy, Somsubhra Nath, Manas Kumar Santra
Cell Death Dis. 2023 Sep; 14(9): 623. Published online 2023 Sep 22. doi: 10.1038/s41419-023-06127-x
PMCID:
PMC10517019
AbstractArticlePDF–5.0M
2.
Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman
Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035
Correction in:
Cell. 2023 May 25; 186(11): 2492.
PMCID:
PMC10156175
AbstractArticle
3.
FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ
Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li
Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831
PMCID:
PMC9491713
AbstractArticlePDF–12M
4.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
5.
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation
Tao Zhou, Tingting Chen, Bin Lai, Wenfeng Zhang, Xi Luo, Ding Xia, Weihua Fu, Jie Xu
Cell Mol Life Sci. 2022 May; 79(5): 268. Published online 2022 May 2. doi: 10.1007/s00018-022-04320-3
PMCID:
PMC9061686
AbstractArticlePDF–8.4M
6.
Ubiquitination of NF-κB p65 by FBXW2 suppresses breast cancer stemness, tumorigenesis, and paclitaxel resistance
Chune Ren, Xue Han, Chao Lu, Tingting Yang, Pengyun Qiao, Yonghong Sun, Zhenhai Yu
Cell Death Differ. 2022 Feb; 29(2): 381–392. Published online 2021 Aug 31. doi: 10.1038/s41418-021-00862-4
PMCID:
PMC8816940
AbstractArticlePDF–7.2M
7.
TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance
Shunjie Xia, Lin Ji, Liye Tao, Yu Pan, Zhongjie Lin, Zhe Wan, Haoqi Pan, Jie Zhao, Liuxin Cai, Junjie Xu, Xiujun Cai
Cell Mol Gastroenterol Hepatol. 2021; 12(3): 1121–1143. Published online 2021 May 5. doi: 10.1016/j.jcmgh.2021.04.016
PMCID:
PMC8350196
AbstractArticlePDF–9.2M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
E3 Ligase FBXW2 Is a New Therapeutic Target in Obesity and Atherosclerosis
Cheng Wang, Wenjing Xu, Yuelin Chao, Minglu Liang, Fengxiao Zhang, Kai Huang
Adv Sci (Weinh) 2020 Oct; 7(20): 2001800. Published online 2020 Aug 26. doi: 10.1002/advs.202001800
PMCID:
PMC7578860
AbstractArticlePDF–5.3M
10.
FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells
Rizwan Saffie, Nan Zhou, Delphine Rolland, Özlem Önder, Venkatesha Basrur, Sydney Campbell, Kathryn E. Wellen, Kojo S.J. Elenitoba-Johnson, Brian C. Capell, Luca Busino
Cancer Res. Author manuscript; available in PMC 2021 Jun 15.
Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2498–2511. Published online 2020 Apr 29. doi: 10.1158/0008-5472.CAN-19-2247
PMCID:
PMC7417195
AbstractArticlePDF–2.1M
11.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
12.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
13.
The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells
Yuan Yin, Chuan-Ming Xie, Hua Li, Mingjia Tan, Guoan Chen, Rachel Schiff, Xiufang Xiong, Yi Sun
Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20528–20538. Published online 2019 Sep 23. doi: 10.1073/pnas.1905973116
PMCID:
PMC6789910
AbstractArticlePDF–1.7M
14.
DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells
Zhou-hua Jiang, Tao Peng, Hai-long Qian, Cai-de Lu, Feng Qiu, Su-zhan Zhang
Cancer Cell Int. 2019; 19: 162. Published online 2019 Jun 14. doi: 10.1186/s12935-019-0878-y
PMCID:
PMC6567580
AbstractArticlePDF–1.1M
15.
FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation
Fei Yang, Jie Xu, Hua Li, Mingjia Tan, Xiufang Xiong, Yi Sun
Nat Commun. 2019; 10: 1382. Published online 2019 Mar 27. doi: 10.1038/s41467-019-09289-5
PMCID:
PMC6437151
AbstractArticlePDF–3.2M
16.
Composition and regulation of the cellular repertoire of SCF ubiquitin ligases
Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2018 Nov 30.
Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016
PMCID:
PMC5711595
AbstractArticlePDF–2.4M
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor
Jie Xu, Weihua Zhou, Fei Yang, Guoan Chen, Haomin Li, Yongchao Zhao, Pengyuan Liu, Hua Li, Mingjia Tan, Xiufang Xiong, Yi Sun
Nat Commun. 2017; 8: 14002. Published online 2017 Jan 16. doi: 10.1038/ncomms14002
PMCID:
PMC5241824
AbstractArticlePDF–5.3M
19.
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva
RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030
PMCID:
PMC4841607
AbstractArticlePDF–1.6M
20.
F-box protein FBXO22 mediates polyubiquitination and degradation of KLF4 to promote hepatocellular carcinoma progression
Xin Tian, Shundong Dai, Jing Sun, Guojiang Jin, Shenyi Jiang, Fandong Meng, Yan Li, Di Wu, Youhong Jiang
Oncotarget. 2015 Sep 8; 6(26): 22767–22775. Published online 2015 May 28. doi: 10.18632/oncotarget.4082
PMCID:
PMC4673198
AbstractArticlePDF–1.5M

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