PMC Links for GEO Profiles (Select 132671558) - PMC

Select item 88495741.

53BP1/shieldin-dependent DSB processing in BRCA1-deficient cells requires CST/Polα/primase fill-in synthesis

Zachary Mirman, Nanda Kumar Sasi, Ashleigh King, J. Ross Chapman, Titia de Lange

Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 51–61. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00812-9

PMCID:: PMC8849574

Abstract Article PDF–6.1M

Select item 84405622.

MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair

Inge de Krijger, Bastian Föhr, Santiago Hernández Pérez, Estelle Vincendeau, Judit Serrat, Alexander Marc Thouin, Vivek Susvirkar, Chloé Lescale, Inés Paniagua, Liesbeth Hoekman, Simranjeet Kaur, Maarten Altelaar, Ludovic Deriano, Alex C. Faesen, Jacqueline J. L. Jacobs

Nat Commun. 2021; 12: 5421. Published online 2021 Sep 14. doi: 10.1038/s41467-021-25724-y

PMCID:: PMC8440562

Abstract Article PDF–2.3M

Select item 82936233.

Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action

Shin-Ya Isobe, Shin-ichiro Hiraga, Koji Nagao, Hiroyuki Sasanuma, Anne D. Donaldson, Chikashi Obuse

Cell Rep. 2021 Jul 13; 36(2): 109383. Published online 2021 Jul 13. doi: 10.1016/j.celrep.2021.109383

PMCID:: PMC8293623

Abstract Article

Select item 81080934.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69892176.

53BP1 cooperation with the REV7-Shieldin complex underpins DNA structure-specific NHEJ

Hind Ghezraoui, Catarina Oliveira, Jordan R. Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos, Sarah Bonham, Benedikt M. Kessler, Sven Rottenberg, Richard J. Cornall, Catherine M. Green, J. Ross Chapman

Nature. Author manuscript; available in PMC 2020 Jan 29.

Published in final edited form as: Nature. 2018 Aug 1; 560(7716): 122–127. Published online 2018 Jul 25. doi: 10.1038/s41586-018-0362-1

PMCID:: PMC6989217

Abstract Article PDF–4.2M

Select item 61566067.

An OB-fold complex controls the repair pathways for DNA double-strand breaks

Shengxian Gao, Sumin Feng, Shaokai Ning, Jingyan Liu, Huayu Zhao, Yixi Xu, Jinfeng Shang, Kejiao Li, Qing Li, Rong Guo, Dongyi Xu

Nat Commun. 2018; 9: 3925. Published online 2018 Sep 25. doi: 10.1038/s41467-018-06407-7

PMCID:: PMC6156606

Abstract Article PDF–1.4M

Select item 61454448.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G. Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier, Mareike Herzog, Jonathan Lam, Abigail Shea, Mukerrem Demir, Qian Wu, Fengtang Yang, Beiyuan Fu, Zhongwu Lai, Gabriel Balmus, Rimma Belotserkovskaya, Violeta Serra, Mark J. O’Connor, Alejandra Bruna, Petra Beli, Luca Pellegrini, Carlos Caldas, Ludovic Deriano, Jacqueline J.L. Jacobs, Yaron Galanty, Stephen P. Jackson

Nat Cell Biol. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Nat Cell Biol. 2018 Aug; 20(8): 954–965. Published online 2018 Jul 18. doi: 10.1038/s41556-018-0140-1

PMCID:: PMC6145444

Abstract Article PDF–2.9M

Select item 61410099.

The Shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J. Pettitt, Alexanda K. Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann, Stefano Annunziato, Dragomir B. Krastev, Feifei Song, Inger Brandsma, Jessica Frankum, Rachel Brough, Alana Sherker, Sébastien Landry, Rachel K. Szilard, Meagan M. Munro, Andrea McEwan, Théo Goullet de Rugy, Zhen-Yuan Lin, Traver Hart, Jason Moffat, Anne-Claude Gingras, Alberto Martin, Haico van Attikum, Jos Jonkers, Christopher J. Lord, Sven Rottenberg, Daniel Durocher

Nature. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Nature. 2018 Aug; 560(7716): 117–121. Published online 2018 Jul 18. doi: 10.1038/s41586-018-0340-7

PMCID:: PMC6141009

Abstract Article PDF–5.1M

Select item 607255910.

53BP1/Rif1/Shieldin counteract DSB resection through CST/Polα-dependent fill-in

Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange

Nature. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Nature. 2018 Aug; 560(7716): 112–116. Published online 2018 Jul 18. doi: 10.1038/s41586-018-0324-7

PMCID:: PMC6072559

Abstract Article PDF–1.8M

Select item 331901511.

Whole genome association scan for genetic polymorphisms influencing information processing speed

Michelle Luciano, Narelle K. Hansell, Jari Lahti, Gail Davies, Sarah E. Medland, Katri Räikkönen, Albert Tenesa, Elisabeth Widen, Kevin A. McGhee, Aarno Palotie, David Liewald, David J. Porteous, John M. Starr, Grant W. Montgomery, Nicholas G. Martin, Johan G. Eriksson, Margaret J. Wright, Ian J. Deary

Biol Psychol. Author manuscript; available in PMC 2012 Apr 4.

Published in final edited form as: Biol Psychol. 2011 Mar; 86(3): 193–202. Published online 2010 Dec 3. doi: 10.1016/j.biopsycho.2010.11.008

PMCID:: PMC3319015

Abstract Article PDF–322K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300858613.

Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

Eric J. Bennett, John Rush, Steven P. Gygi, J. Wade Harper

Cell. Author manuscript; available in PMC 2011 Dec 10.

Published in final edited form as: Cell. 2010 Dec 10; 143(6): 951–965. doi: 10.1016/j.cell.2010.11.017

PMCID:: PMC3008586

Abstract Article PDF–3.0M

Select item 298946114.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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