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Select item 113157651.

SoDCoD: a comprehensive database of Cu/Zn superoxide dismutase conformational diversity caused by ALS-linked gene mutations and other perturbations

Riko Tabuchi, Yurika Momozawa, Yuki Hayashi, Hisashi Noma, Hidenori Ichijo, Takao Fujisawa

Database (Oxford) 2024; 2024: 0. Published online 2024 Aug 8. doi: 10.1093/database/baae064

PMCID:: PMC11315765

Abstract Article PDF–17M

Select item 112858182.

Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells

Luke McAlary, Jeremy R. Nan, Clay Shyu, Mine Sher, Steven S. Plotkin, Neil R. Cashman

Open Biol. 2024 Jun; 14(6): 230418. Published online June 5, 2024. doi: 10.1098/rsob.230418

PMCID:: PMC11285818

Abstract Article PDF–3.2M

Select item 111866363.

SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells

Linda Zhang, Joanne I Hsu, Etienne D Braekeleer, Chun-Wei Chen, Tajhal D Patel, Alejandra G Martell, Anna G Guzman, Katharina Wohlan, Sarah M Waldvogel, Hidetaka Uryu, Ayala Tovy, Elsa Callen, Rebecca L Murdaugh, Rosemary Richard, Sandra Jansen, Lisenka Vissers, Bert BA de Vries, Andre Nussenzweig, Shixia Huang, Cristian Coarfa, Jamie Anastas, Koichi Takahashi, George Vassiliou, Margaret A Goodell

eLife. 2024; 12: RP91611. Published online 2024 Jun 18. doi: 10.7554/eLife.91611

PMCID:: PMC11186636

Abstract Article PDF–1.5M

Select item 111317874.

Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells

P. Vigilanza, K. Aquilano, G. Rotilio, M. R. Ciriolo

Cell Mol Life Sci. 2008 Mar; 65(6): 991–1004. Published online 2008 Feb 1. doi: 10.1007/s00018-008-7526-3

PMCID:: PMC11131787

Abstract Article PDF–2.1M

Select item 111137125.

Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells

Vinod Sundaramoorthy, Adam K. Walker, Justin Yerbury, Kai Ying Soo, Manal A. Farg, Vy Hoang, Rafaa Zeineddine, Damian Spencer, Julie D. Atkin

Cell Mol Life Sci. 2013 Nov; 70(21): 4181–4195. Published online 2013 Jun 14. doi: 10.1007/s00018-013-1385-2

PMCID:: PMC11113712

Abstract Article PDF–1.7M

Select item 111053736.

Network mapping of the conformational heterogeneity of SOD1 by deploying statistical cluster analysis of FTIR spectra

Sourav Chowdhury, Sagnik Sen, Amrita Banerjee, Vladimir N. Uversky, Ujjwal Maulik, Krishnananda Chattopadhyay

Cell Mol Life Sci. 2019 Oct; 76(20): 4145–4154. Published online 2019 Apr 22. doi: 10.1007/s00018-019-03108-2

PMCID:: PMC11105373

Abstract Article PDF–1.2M

Select item 110879677.

Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1

Edward Pokrishevsky, Michéle G. DuVal, Luke McAlary, Sarah Louadi, Silvia Pozzi, Andrei Roman, Steven S. Plotkin, Anke Dijkstra, Jean-Pierre Julien, W. Ted Allison, Neil R. Cashman

J Biol Chem. 2024 May; 300(5): 107207. Published online 2024 Mar 22. doi: 10.1016/j.jbc.2024.107207

PMCID:: PMC11087967

Abstract Article PDF–3.8M

Select item 109557258.

Engineering a monobody specific to monomeric Cu/Zn‐superoxide dismutase associated with amyotrophic lateral sclerosis

Hiroshi Amesaka, Mizuho Hara, Yuki Sakai, Atsuko Shintani, Kaori Sue, Tomoyuki Yamanaka, Shun‐ichi Tanaka, Yoshiaki Furukawa

Protein Sci. 2024 Apr; 33(4): e4961. Published online 2024 Mar 21. doi: 10.1002/pro.4961

PMCID:: PMC10955725

Abstract Article PDF–11M

Select item 109117279.

Superoxide Dismutase (rs2070424, rs4880, rs2536512) and Catalase (rs794316, rs1001179) SNPs and their Association with Breast Cancer Risk: Findings from a Hospital Based Case-Control Study

Kailas D Datkhile, Rashmi A Gudur, Suresh J Bhosale, Anand Krishnarao Gudur, Pratik P Durgawale, Nilam J Jagdale, Ashwini L More, Satish R Patil

Asian Pac J Cancer Prev. 2024; 25(1): 175–184. doi: 10.31557/APJCP.2024.25.1.175

PMCID:: PMC10911727

Abstract Article PDF–508K

Select item 1076495810.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 1074656211.

ALS-linked SOD1 mutations impair mitochondrial-derived vesicle formation and accelerate aging

Ying Guo, Teng Guan, Qiang Yu, Nitesh Sanghai, Kashfia Shafiq, Meiyu Li, Xin Jiao, Donghui Na, Guohui Zhang, Jiming Kong

Redox Biol. 2024 Feb; 69: 102972. Published online 2023 Nov 24. doi: 10.1016/j.redox.2023.102972

PMCID:: PMC10746562

Abstract Article PDF–11M

Select item 1069136812.

The evaluation of superoxide dismutase 1 gene insertion/deletion variant in athletes

Ayşe Feyda Nursal, Şaban Ünver, Serbülent Yiğit, Ömür Mevlüt Orhan, Tülin Atan

Rev Assoc Med Bras (1992) 2023; 69(12): e20230575. Published online 2023 Nov 24. doi: 10.1590/1806-9282.20230575

PMCID:: PMC10691368

Abstract Article PDF–249K

Select item 1064585313.

Extreme diversity of 12 cations in folding ALS-linked hSOD1 unveils novel hSOD1-dependent mechanisms for Fe²⁺/Cu²⁺-induced cytotoxicity

Liangzhong Lim, Jian Kang, Jianxing Song

Sci Rep. 2023; 13: 19868. Published online 2023 Nov 14. doi: 10.1038/s41598-023-47338-8

PMCID:: PMC10645853

Abstract Article PDF–4.4M

Select item 1042180314.

Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers

Peter Bede, Dorothée Lulé, Hans-Peter Müller, Ee Ling Tan, Johannes Dorst, Albert C. Ludolph, Jan Kassubek

J Neurol. 2023; 270(9): 4235–4247. Published online 2023 May 13. doi: 10.1007/s00415-023-11764-5

PMCID:: PMC10421803

Abstract Article PDF–1.0M

Select item 1037798415.

CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A

Valentina La Cognata, Agata Grazia D’Amico, Grazia Maugeri, Giovanna Morello, Maria Guarnaccia, Benedetta Magrì, Eleonora Aronica, Velia D’Agata, Sebastiano Cavallaro

Cells. 2023 Jul; 12(14): 1813. Published online 2023 Jul 9. doi: 10.3390/cells12141813

PMCID:: PMC10377984

Abstract Article PDF–7.7M

Select item 1036863516.

Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients

Volkan Yazar, Julia K. Kühlwein, Antje Knehr, Veselin Grozdanov, Arif B. Ekici, Albert C. Ludolph, Karin M. Danzer

Sci Rep. 2023; 13: 12019. Published online 2023 Jul 25. doi: 10.1038/s41598-023-38684-8

PMCID:: PMC10368635

Abstract Article PDF–2.3M

Select item 1027025417.

Protein kinetics of superoxide dismutase‐1 in familial and sporadic amyotrophic lateral sclerosis

Cindy V. Ly, Margaret D. Ireland, Wade K. Self, James Bollinger, Jennifer Jockel‐Balsarotti, Hillary Herzog, Peggy Allred, Leah Miller, Michael Doyle, Isabel Anez‐Bruzual, Bhavesh Trikamji, Ted Hyman, Tyler Kung, Katherine Nicholson, Robert C. Bucelli, Bruce W. Patterson, Randall J. Bateman, Timothy M. Miller

Ann Clin Transl Neurol. 2023 Jun; 10(6): 1012–1024. Published online 2023 Apr 29. doi: 10.1002/acn3.51784

PMCID:: PMC10270254

Abstract Article PDF–795K

Select item 1023742218.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233