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Select item 110670251.

TRAF3 loss-of-function reveals the noncanonical NF-κB pathway as a therapeutic target in diffuse large B cell lymphoma

Michael Y. Li, Lauren C. Chong, Gerben Duns, Andrew Lytle, Bruce Woolcock, Aixiang Jiang, Adèle Telenius, Susana Ben-Neriah, Waqas Nawaz, Graham W. Slack, Ingrid Elisia, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2320421121. Published online 2024 Apr 25. doi: 10.1073/pnas.2320421121

PMCID:: PMC11067025

Abstract Article PDF–4.2M

Select item 105572792.

Effects of TRAF3 on the proliferation and migration of lung adenocarcinoma depend partly on pyroptosis

Wangjia Wang, Shiqi Wang, Min Wang, Yamei Ma, Wanting Hu, Binsha Wu, Chichi Li, Dan Zhang

BMC Cancer. 2023; 23: 942. Published online 2023 Oct 5. doi: 10.1186/s12885-023-11468-z

PMCID:: PMC10557279

Abstract Article PDF–2.5M

Select item 105013563.

Circular RNA SMARCA5 inhibits cholangiocarcinoma via microRNA-95-3p/tumor necrosis factor receptor associated factor 3 axis

Guangxin Wang, Xia Gao, Zhijun Sun, Tianyou He, Chaogang Huang, Shouwei Li, Haocheng Long

Anticancer Drugs. 2023 Oct; 34(9): 1002–1009. Published online 2023 Jan 24. doi: 10.1097/CAD.0000000000001487

PMCID:: PMC10501356

Abstract Article PDF–1.1M

Select item 101309054.

TRAF3–EWSR1 signaling axis acts as a checkpoint on germinal center responses

Yanchuan Li, Lele Zhu, Chun-Jung Ko, Jin-Young Yang, Hongjiao Wang, Ganiraju Manyam, Jing Wang, Xuhong Cheng, Shuli Zhao, Zuliang Jie

J Exp Med. 2023 Aug 7; 220(8): e20221483. Published online 2023 Apr 25. doi: 10.1084/jem.20221483

Correction in:: J Exp Med. 2023 Aug 7; 220(8): e2022148307122023c.

PMCID:: PMC10130905

Abstract Article PDF–6.2M

Select item 99730305.

Heterogeneous Nuclear Protein U Degraded the m⁶A Methylated TRAF3 Transcript by YTHDF2 To Promote Porcine Epidemic Diarrhea Virus Replication

Hongchao Zhou, Yuchao Yan, Jie Gao, Mingrui Ma, Yi Liu, Xiaojie Shi, Qi Zhang, Xingang Xu

J Virol. 2023 Feb; 97(2): e01751-22. Published online 2023 Feb 8. doi: 10.1128/jvi.01751-22

PMCID:: PMC9973030

Abstract Article PDF–4.2M

Select item 99500636.

TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion

Wenwen Zheng, Zhenbang Zhou, Yajuan Rui, Runxin Ye, Fengyan Xia, Fei Guo, Xiaoman Liu, Jiaming Su, Meng Lou, Xiao-Fang Yu

Signal Transduct Target Ther. 2023; 8: 79. Published online 2023 Feb 24. doi: 10.1038/s41392-022-01287-2

PMCID:: PMC9950063

Abstract Article PDF–5.5M

Select item 95080957.

Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy

Xuyuan Wang, Li Jiang, Guangwen Wang, Wenjun Shi, Yuzhen Hu, Bo Wang, Xianying Zeng, Guobin Tian, Guohua Deng, Jianzhong Shi, Liling Liu, Chengjun Li, Hualan Chen

Cell Mol Immunol. 2022 Oct; 19(10): 1168–1184. Published online 2022 Sep 2. doi: 10.1038/s41423-022-00906-w

PMCID:: PMC9508095

Abstract Article PDF–4.4M

Select item 94895408.

Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-0110634

Wei Ji, Yueyang Lu, Zhuoyi Ma, Ke Gan, Yan Liu, Yue Cheng, Junliang Xu, Shijia Liu, Yunke Guo, Shanhang Han, Zengyan Zhao, Hanmei Xu, Weiyan Qi

J Orthop Translat. 2022 Sep; 36: 132–144. Published online 2022 Sep 16. doi: 10.1016/j.jot.2022.05.007

PMCID:: PMC9489540

Abstract Article PDF–4.1M

Select item 94208699.

BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS

Jing-Ping Huang, Jing Li, Yan-Ping Xiao, Liang-Guo Xu

Front Immunol. 2022; 13: 972184. Published online 2022 Aug 15. doi: 10.3389/fimmu.2022.972184

PMCID:: PMC9420869

Abstract Article PDF–21M

Select item 927418710.

MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway

Wei Liu, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang, Pengtao Jiao

Cell Commun Signal. 2022; 20: 103. Published online 2022 Jul 12. doi: 10.1186/s12964-022-00922-3

PMCID:: PMC9274187

Abstract Article PDF–5.7M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523512.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 883246113.

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis

Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun

Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247

PMCID:: PMC8832461

Abstract Article

Select item 882889514.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 879957015.

A20 undermines alternative NF-κB activity and expression of anti-apoptotic genes in Helicobacter pylori infection

Michelle C. C. Lim, Gunter Maubach, Anna M. Birkl-Toeglhofer, Johannes Haybaeck, Michael Vieth, Mchael Naumann

Cell Mol Life Sci. 2022 Feb; 79(2): 102. Published online 2022 Jan 28. doi: 10.1007/s00018-022-04139-y

PMCID:: PMC8799570

Abstract Article PDF–2.3M

Select item 879572916.

TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

Jian-Hong Shi, Chen Ling, Ting-Ting Wang, Li-Nuo Zhang, Wen-Wen Liu, Yan Qin, Ying-Hui Tan, Nai-Peng Cui, Zhi-Yu Ni

Cell Death Dis. 2022 Jan; 13(1): 93. Published online 2022 Jan 28. doi: 10.1038/s41419-022-04539-9

PMCID:: PMC8795729

Abstract Article PDF–5.3M

Select item 864604217.

N4BP3 Regulates RIG-I-Like Receptor Antiviral Signaling Positively by Targeting Mitochondrial Antiviral Signaling Protein

Chen Wang, Ting Ling, Ni Zhong, Liang-Guo Xu

Front Microbiol. 2021; 12: 770600. Published online 2021 Nov 22. doi: 10.3389/fmicb.2021.770600

PMCID:: PMC8646042

Abstract Article PDF–10M

Select item 856401418.

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Yingying Liu, Samantha Gokhale, Jaeyong Jung, Sining Zhu, Chang Luo, Debanjan Saha, Jessie Yanxiang Guo, Huaye Zhang, Saw Kyin, Wei-Xing Zong, Eileen White, Ping Xie

Front Immunol. 2021; 12: 670338. Published online 2021 Oct 20. doi: 10.3389/fimmu.2021.670338

PMCID:: PMC8564014

Abstract Article PDF–18M

Select item 849141319.

Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity

Chun-Yang Lin, Meng-Cen Shih, Hung-Chun Chang, Kuan-Jung Lin, Lin-Fang Chen, Sheng-Wen Huang, Mei-Lin Yang, Sheng-Kai Ma, Ai-Li Shiau, Jen-Ren Wang, Kuan-Ru Chen, Pin Ling

J Biomed Sci. 2021; 28: 66. Published online 2021 Oct 5. doi: 10.1186/s12929-021-00764-0