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Select item 107988581.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106812593.

eIF2A represses cell wall biogenesis gene expression in Saccharomyces cerevisiae

Laura Meyer, Baptiste Courtin, Maïté Gomard, Abdelkader Namane, Emmanuelle Permal, Gwenael Badis, Alain Jacquier, Micheline Fromont-Racine

PLoS One. 2023; 18(11): e0293228. Published online 2023 Nov 27. doi: 10.1371/journal.pone.0293228

PMCID:: PMC10681259

Abstract Article PDF–2.5M

Select item 104712284.

Identification and characterization of protein interactions with the major Niemann–Pick type C disease protein in yeast reveals pathways of therapeutic potential

Natalie Hammond, Jamie Snider, Igor Stagljar, Kevin Mitchell, Kirill Lagutin, Matthew Jessulat, Mohan Babu, Paul H Teesdale-Spittle, Jeffrey P Sheridan, Stephen L Sturley, Andrew B Munkacsi

Genetics. 2023 Sep; 225(1): iyad129. Published online 2023 Jul 13. doi: 10.1093/genetics/iyad129

PMCID:: PMC10471228

Abstract Article PDF–32M

Select item 102977005.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922106.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99473338.

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation

Guido Barbieri, Julien Simon, Cristina R. Lupusella, Fabio Pereira, Francesco Elia, Hadar Meyer, Maya Schuldiner, Steven D. Hanes, Duy Nguyen, Volkhard Helms, Karin Römisch

J Biol Chem. 2023 Mar; 299(3): 102895. Published online 2023 Jan 11. doi: 10.1016/j.jbc.2023.102895

PMCID:: PMC9947333

Abstract Article PDF–1.7M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 900791710.

Identification of 14-3-3 Proteins, Polo kinase, and RNA-binding protein Pes4 as Key Regulators of Meiotic Commitment in Budding Yeast

Janardan N. Gavade, Chris M. Puccia, S. Grace Herod, Jonathan C. Trinidad, Luke E. Berchowitz, Soni Lacefield

Curr Biol. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Curr Biol. 2022 Apr 11; 32(7): 1534–1547.e9. Published online 2022 Mar 2. doi: 10.1016/j.cub.2022.02.022

PMCID:: PMC9007917

Abstract Article PDF–2.2M

Select item 843946511.

Cancer associated mutations in Sec61γ alter the permeability of the ER translocase

Christopher M. Witham, Aleshanee L. Paxman, Lamprini Baklous, Robert F. L. Steuart, Benjamin L. Schulz, Carl J. Mousley

PLoS Genet. 2021 Aug; 17(8): e1009780. Published online 2021 Aug 30. doi: 10.1371/journal.pgen.1009780

PMCID:: PMC8439465

Abstract Article PDF–2.6M

Select item 838278412.

Cryo-EM structures of the endoplasmic reticulum membrane complex

Lin Bai, Huilin Li

FEBS J. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: FEBS J. 2022 Jan; 289(1): 102–112. Published online 2021 Mar 6. doi: 10.1111/febs.15786

PMCID:: PMC8382784

Abstract Article PDF–2.5M

Select item 823621113.

Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62

Samuel Itskanov, Katie M. Kuo, James C. Gumbart, Eunyong Park

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Jul 4.

Published in final edited form as: Nat Struct Mol Biol. 2021 Feb; 28(2): 162–172. Published online 2021 Jan 4. doi: 10.1038/s41594-020-00541-x

PMCID:: PMC8236211

Abstract Article PDF–9.8M

Select item 809411714.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130