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Select item 108264461.

DNMT3a‐mediated methylation of PPARγ promote intervertebral disc degeneration by regulating the NF‐κB pathway

Peng Cheng, Hang‐Zhi Wei, Hai‐Wei Chen, Zhi‐Qiang Wang, Peng Mao, Hai‐Hong Zhang

J Cell Mol Med. 2024 Jan; 28(2): e18048. Published online 2023 Nov 20. doi: 10.1111/jcmm.18048

PMCID:: PMC10826446

Abstract Article PDF–26M

Select item 96940312.

Identification of Epigenetic Interactions between MicroRNA-30c-5p and DNA Methyltransferases in Neuropathic Pain

Raquel Francés, Jorge Mata-Garrido, Roberto de la Fuente, María Carcelén, Miguel Lafarga, María Teresa Berciano, Raquel García, María A. Hurlé, Mónica Tramullas

Int J Mol Sci. 2022 Nov; 23(22): 13994. Published online 2022 Nov 13. doi: 10.3390/ijms232213994

PMCID:: PMC9694031

Abstract Article PDF–1.9M

Select item 79450153.

DNA Methyltransferase 3A Is Involved in the Sustained Effects of Chronic Stress on Synaptic Functions and Behaviors

Jing Wei, Jia Cheng, Nicholas J Waddell, Zi-Jun Wang, Xiaodong Pang, Qing Cao, Aiyi Liu, Javed M Chitaman, Kristen Abreu, Rahul Singh Jasrotia, Lara J Duffney, Jinfeng Zhang, David M Dietz, Jian Feng, Zhen Yan

Cereb Cortex. 2021 Apr; 31(4): 1998–2012. Published online 2020 Nov 24. doi: 10.1093/cercor/bhaa337

PMCID:: PMC7945015

Abstract Article PDF–1.8M

Select item 67035234.

Change in MicroRNAs Associated with Neuronal Adaptive Responses in the Nucleus Accumbens under Neuropathic Pain

Satoshi Imai, Mai Saeki, Makoto Yanase, Hiroshi Horiuchi, Minako Abe, Michiko Narita, Naoko Kuzumaki, Tsutomu Suzuki, Minoru Narita

J Neurosci. 2011 Oct 26; 31(43): 15294–15299. doi: 10.1523/JNEUROSCI.0921-11.2011

PMCID:: PMC6703523

Abstract Article PDF–1.3M

Select item 65209895.

Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Patricia Heyn, Clare V. Logan, Adeline Fluteau, Rachel C. Challis, Tatsiana Auchynnikava, Carol-Anne Martin, Joseph A. Marsh, Francesca Taglini, Fiona Kilanowski, David A. Parry, Valerie Cormier-Daire, Chin-To Fong, Kate Gibson, Vivian Hwa, Lourdes Ibáñez, Stephen P. Robertson, Giorgia Sebastiani, Juri Rappsilber, Robin C. Allshire, Martin A.M. Reijns, Andrew Dauber, Duncan Sproul, Andrew P. Jackson

Nat Genet. Author manuscript; available in PMC 2019 May 26.

Published in final edited form as: Nat Genet. 2019 Jan; 51(1): 96–105. Published online 2018 Nov 26. doi: 10.1038/s41588-018-0274-x

PMCID:: PMC6520989

Abstract Article PDF–2.4M

Select item 62963276.

Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A

Marianna Szemes, Anthony R. Dallosso, Zsombor Melegh, Thomas Curry, Yifan Li, Caroline Rivers, James Uney, Ann-Sophie Mägdefrau, Karolin Schwiderski, Ji H. Park, Keith W. Brown, Jayasha Shandilya, Stefan G. E. Roberts, Karim Malik

Hum Mol Genet. 2013 Jan 1; 22(1): 74–83. Published online 2012 Oct 5. doi: 10.1093/hmg/dds403

PMCID:: PMC6296327

Abstract Article PDF–471K

Select item 56765007.

DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1.2 expression in spinal cord dorsal horn

Xue-Rong Miao, Long-Chang Fan, Shaogen Wu, Qing-Xiang Mao, Zhen Li, Brianna M Lutz, Jitian Xu, Zhi-Jie Lu, Yuan-Xiang Tao

Mol Pain. 2017; 13: 1744806917740681. Published online 2017 Nov 7. doi: 10.1177/1744806917740681

Correction in:: Mol Pain. 2020; 16: 1744806920963460.

PMCID:: PMC5676500

Abstract Article PDF–834K

Select item 55618318.

Chronic cerebrovascular hypoperfusion affects global DNA methylation and histone acetylation in rat brain

Xiangmei Wu, Jing Sun, Liang Li

Neurosci Bull. 2013 Dec; 29(6): 685–692. Published online 2013 May 28. doi: 10.1007/s12264-013-1345-8

PMCID:: PMC5561831

Abstract Article PDF–936K

Select item 54355419.

Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons

Linlin Sun, Jian-Yuan Zhao, Xiyao Gu, Lingli Liang, Shaogen Wu, Kai Mo, Jian Feng, Weixiang Guo, Jun Zhang, Alex Bekker, Xinyu Zhao, Eric J Nestler, Yuan-Xiang Tao

Pain. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Pain. 2017 Jun; 158(6): 1153–1165. doi: 10.1097/j.pain.0000000000000894

PMCID:: PMC5435541

Abstract Article PDF–1.5M

Select item 534497410.

DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons

Jian-Yuan Zhao, Lingli Liang, Xiyao Gu, Zhisong Li, Shaogen Wu, Linlin Sun, Fidelis E. Atianjoh, Jian Feng, Kai Mo, Shushan Jia, Brianna Marie Lutz, Alex Bekker, Eric J. Nestler, Yuan-Xiang Tao

Nat Commun. 2017; 8: 14712. Published online 2017 Mar 8. doi: 10.1038/ncomms14712

Correction in:: Nat Commun. 2020; 11: 4696.

PMCID:: PMC5344974

Abstract Article PDF–1.7M

Select item 464983111.

DNA methylation and differential gene regulation in photoreceptor cell death

P Farinelli, A Perera, B Arango-Gonzalez, D Trifunovic, M Wagner, T Carell, M Biel, E Zrenner, S Michalakis, F Paquet-Durand, P A R Ekström

Cell Death Dis. 2014 Dec; 5(12): e1558. Published online 2014 Dec 4. doi: 10.1038/cddis.2014.512

PMCID:: PMC4649831

Abstract Article PDF–4.9M

Select item 438367512.

DNMT3A mutational status affects the results of dose-escalated induction therapy in acute myelogenous leukemia

Alison R. Sehgal, Phyllis A. Gimotty, Jianhua Zhao, Jing-Mei Hsu, Robert Daber, JD Morrissette, Selina Luger, Alison W. Loren, Martin Carroll

Clin Cancer Res. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Clin Cancer Res. 2015 Apr 1; 21(7): 1614–1620. Published online 2015 Jan 21. doi: 10.1158/1078-0432.CCR-14-0327

PMCID:: PMC4383675

Abstract Article PDF–666K

Select item 430410813.

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation

Allison Mayle, Liubin Yang, Benjamin Rodriguez, Ting Zhou, Edmund Chang, Choladda V. Curry, Grant A. Challen, Wei Li, David Wheeler, Vivienne I. Rebel, Margaret A. Goodell

Blood. 2015 Jan 22; 125(4): 629–638. Prepublished online 2014 Nov 21. doi: 10.1182/blood-2014-08-594648

PMCID:: PMC4304108

Abstract Article

Select item 428193514.

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

Igor P. Pogribny, Athena Starlard-Davenport, Volodymyr P. Tryndyak, Tao Han, Sharon A. Ross, Ivan Rusyn, Frederick A. Beland

Lab Invest. Author manuscript; available in PMC 2015 Jan 2.

Published in final edited form as: Lab Invest. 2010 Oct; 90(10): 1437–1446. Published online 2010 Jun 14. doi: 10.1038/labinvest.2010.113

PMCID:: PMC4281935

Abstract Article PDF–547K

Select item 421329215.

Effects of Acute Ethanol Exposure on Anxiety Measures and Epigenetic Modifiers in the Extended Amygdala of Adolescent Rats

Amul J. Sakharkar, Lei Tang, Huaibo Zhang, Ying Chen, Dennis R Grayson, Subhash C. Pandey

Int J Neuropsychopharmacol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Int J Neuropsychopharmacol. 2014 Dec; 17(12): 2057–2067. Published online 2014 Jun 26. doi: 10.1017/S1461145714001047

PMCID:: PMC4213292

Abstract Article PDF–1.3M

Select item 419802416.

Playing TETris with DNA modifications

Benjamin Delatte, Rachel Deplus, François Fuks

EMBO J. 2014 Jun 2; 33(11): 1198–1211. Published online 2014 May 13. doi: 10.15252/embj.201488290

PMCID:: PMC4198024

Abstract Article PDF–787K

Select item 405520317.

Effects of topiramate on ethanol-cocaine interactions and DNA methyltransferase gene expression in the rat prefrontal cortex

V Echeverry-Alzate, E Giné, K M Bühler, J Calleja-Conde, P Olmos, M A Gorriti, R Nadal, F Rodríguez de Fonseca, J A López-Moreno

Br J Pharmacol. 2014 Jun; 171(12): 3023–3036. Published online 2014 May 27. doi: 10.1111/bph.12636

PMCID:: PMC4055203

Abstract Article PDF–1.7M

Select item 401897618.

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits WT DNMT3A by Blocking its Ability to Form Active Tetramers

David A. Russler-Germain, David H. Spencer, Margaret A. Young, Tamara L. Lamprecht, Christopher A. Miller, Robert Fulton, Matthew R. Meyer, Petra Erdmann-Gilmore, R. Reid Townsend, Richard K. Wilson, Timothy J. Ley

Cancer Cell. Author manuscript; available in PMC 2015 Apr 14.

Published in final edited form as: Cancer Cell. 2014 Apr 14; 25(4): 442–454. Published online 2014 Mar 20. doi: 10.1016/j.ccr.2014.02.010