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Select item 111316871.

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

L. Verstrepen, T. Bekaert, T.-L. Chau, J. Tavernier, A. Chariot, R. Beyaert

Cell Mol Life Sci. 2008 Oct; 65(19): 2964–2978. Published online 2008 Jun 6. doi: 10.1007/s00018-008-8064-8

PMCID:: PMC11131687

Abstract Article PDF–2.1M

Select item 101707942.

Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models

Biwei Wei, Zhou Su, Huiying Yang, Yong Feng, Chunmei Meng, Zhihai Liang

Biol Direct. 2023; 18: 23. Published online 2023 May 10. doi: 10.1186/s13062-023-00380-y

PMCID:: PMC10170794

Abstract Article PDF–3.3M

Select item 89739383.

Bone marrow mesenchymal stem cells-derived exosomal microRNA-124-3p attenuates hypoxic-ischemic brain damage through depressing tumor necrosis factor receptor associated factor 6 in newborn rats

Weijie Min, Yina Wu, Yibin Fang, Bo Hong, Dongwei Dai, Yu Zhou, Jianmin Liu, Qiang Li

Bioengineered. 2022; 13(2): 3195–3207. Published online 2022 Jan 22. doi: 10.1080/21655979.2021.2016094

PMCID:: PMC8973938

Abstract Article PDF–3.3M

Select item 85244304.

Role of tumor necrosis factor receptor-associated factor 6 in pyroptosis during acute pancreatitis

Biwei Wei, Yahui Gong, Huiying Yang, Jie Zhou, Zhou Su, Zhihai Liang

Mol Med Rep. 2021 Dec; 24(6): 848. Published online 2021 Oct 11. doi: 10.3892/mmr.2021.12488

PMCID:: PMC8524430

Abstract Article PDF–4.5M

Select item 77556055.

The Interaction of TRAF6 With Neuroplastin Promotes Spinogenesis During Early Neuronal Development

Sampath Kumar Vemula, Ayse Malci, Lennart Junge, Anne-Christin Lehmann, Ramya Rama, Johannes Hradsky, Ricardo A. Matute, André Weber, Matthias Prigge, Michael Naumann, Michael R. Kreutz, Constanze I. Seidenbecher, Eckart D. Gundelfinger, Rodrigo Herrera-Molina

Front Cell Dev Biol. 2020; 8: 579513. Published online 2020 Dec 9. doi: 10.3389/fcell.2020.579513

PMCID:: PMC7755605

Abstract Article PDF–11M

Select item 71687806.

Targeting spinal TRAF6 expression attenuates chronic visceral pain in adult rats with neonatal colonic inflammation

Rui-Xia Weng, Wei Chen, Jia-Ni Tang, Qian Sun, Meng Li, Xue Xu, Ping-An Zhang, Ying Zhang, Chuang-Ying Hu, Guang-Yin Xu

Mol Pain. 2020; 16: 1744806920918059. Published online 2020 Apr 16. doi: 10.1177/1744806920918059

PMCID:: PMC7168780

Abstract Article PDF–607K

Select item 70860327.

TNF receptor–associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation

Sabrina Semmler, Myriam Gagné, Pranav Garg, Sarah R. Pickles, Charlotte Baudouin, Emeline Hamon-Keromen, Laurie Destroismaisons, Yousra Khalfallah, Mathilde Chaineau, Elise Caron, Andrew N. Bayne, Jean-François Trempe, Neil R. Cashman, Alexandra T. Star, Arsalan S. Haqqani, Thomas M. Durcan, Elizabeth M. Meiering, Janice Robertson, Nathalie Grandvaux, Steven S. Plotkin, Heidi M. McBride, Christine Vande Velde

J Biol Chem. 2020 Mar 20; 295(12): 3808–3825. Published online 2020 Feb 6. doi: 10.1074/jbc.RA119.011215

PMCID:: PMC7086032

Abstract Article PDF–3.7M

Select item 67727658.

Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) Deficiency Results in Exencephaly and Is Required for Apoptosis within the Developing CNS

Mark A. Lomaga, Jeffrey T. Henderson, Andrew J. Elia, Jennifer Robertson, Ryan S. Noyce, Wen-Chen Yeh, Tak W. Mak

J Neurosci. 2000 Oct 1; 20(19): 7384–7393. doi: 10.1523/JNEUROSCI.20-19-07384.2000

PMCID:: PMC6772765

Abstract Article PDF–2.4M

Select item 59705479.

MicroRNA-194 Inhibits Lipopolysaccharide-Induced Inflammatory Response in Nucleus Pulposus Cells of the Intervertebral Disc by Targeting TNF Receptor-Associated Factor 6 (TRAF6)

Lili Kong, Mingxiao Sun, Zhaofu Jiang, Liming Li, Bing Lu

Med Sci Monit. 2018; 24: 3056–3067. Published online 2018 May 10. doi: 10.12659/MSM.907280

PMCID:: PMC5970547

Abstract Article PDF–760K

Select item 564267510.

Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity

Qi Ma, Hongyu Ruan, Lisheng Peng, Mingjie Zhang, Michaela U. Gack, Wei-Dong Yao

Proc Natl Acad Sci U S A. 2017 Oct 10; 114(41): E8760–E8769. Published online 2017 Sep 25. doi: 10.1073/pnas.1620153114

PMCID:: PMC5642675

Abstract Article PDF–3.5M

Select item 515962211.

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

Robert Wilson, Stefan H. Geyer, Lukas Reissig, Julia Rose, Dorota Szumska, Emily Hardman, Fabrice Prin, Christina McGuire, Ramiro Ramirez-Solis, Jacqui White, Antonella Galli, Catherine Tudor, Elizabeth Tuck, Cecilia Icoresi Mazzeo, James C. Smith, Elizabeth Robertson, David J. Adams, Timothy Mohun, Wolfgang J. Weninger

Version 2. Wellcome Open Res. 2016; 1: 1. Published online 2017 Feb 27. doi: 10.12688/wellcomeopenres.9899.2

PMCID:: PMC5159622

Abstract Article PDF–7.4M

Select item 508651312.

MicroRNA-146a Contributes to SCI Recovery via Regulating TRAF6 and IRAK1 Expression

Jinsong Wei, Jiafeng Wang, Yulan Zhou, Shouquan Yan, Keshen Li, Hongsheng Lin

Biomed Res Int. 2016; 2016: 4013487. Published online 2016 Oct 17. doi: 10.1155/2016/4013487

PMCID:: PMC5086513

Abstract Article PDF–1.0M

Select item 489538513.

The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling

Yan-Xiao Ji, Peng Zhang, Xiao-Jing Zhang, Yi-Chao Zhao, Ke-Qiong Deng, Xi Jiang, Pi-Xiao Wang, Zan Huang, Hongliang Li

Nat Commun. 2016; 7: 11267. Published online 2016 Jun 1. doi: 10.1038/ncomms11267

PMCID:: PMC4895385

Abstract Article PDF–6.0M

Select item 484876214.

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660

PMCID:: PMC4848762

Abstract Article PDF–2.8M

Select item 434837715.

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

Dongsheng Wu, Camilla Cerutti, Miguel A Lopez-Ramirez, Gareth Pryce, Josh King-Robson, Julie E Simpson, Susanne MA van der Pol, Mark C Hirst, Helga E de Vries, Basil Sharrack, David Baker, David K Male, Gregory J Michael, Ignacio A Romero

J Cereb Blood Flow Metab. 2015 Mar; 35(3): 412–423. Published online 2014 Dec 17. doi: 10.1038/jcbfm.2014.207

PMCID:: PMC4348377

Abstract Article PDF–920K

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 372119517.

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Monika Schneider, Albert G Zimmermann, Reid A Roberts, Lu Zhang, Karen V Swanson, Haitao Wen, Beckley K Davis, Irving C Allen, Eda K Holl, Zhengmao Ye, Adeeb H Rahman, Brian J Conti, Timothy K Eitas, Beverly H Koller, Jenny P-Y Ting

Nat Immunol. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Nat Immunol. 2012 Sep; 13(9): 823–831. Published online 2012 Aug 5. doi: 10.1038/ni.2378

PMCID:: PMC3721195

Abstract Article PDF–967K

Select item 344253818.

Caveosomal Oxidative Stress Causes Src-p21^ras Activation and Lysine 63 TRAF6 Protein Polyubiquitination in Iron-induced M1 Hepatic Macrophage Activation

Shuping Zhong, Jun Xu, Peggy Li, Hidekazu Tsukamoto

J Biol Chem. 2012 Sep 14; 287(38): 32078–32084. Published online 2012 Jul 24. doi: 10.1074/jbc.M112.377358

PMCID:: PMC3442538

Abstract Article PDF–1.5M

Select item 339495219.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Abstract Article PDF–3.3M

Select item 326170820.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

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