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Items: 20

1.
An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase
Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang
iScience. 2022 Feb 18; 25(2): 103813. Published online 2022 Jan 25. doi: 10.1016/j.isci.2022.103813
PMCID:
PMC8844827
AbstractArticlePDF–6.0M
2.
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter
Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra
Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1
PMCID:
PMC8629785
AbstractArticlePDF–10M
3.
Chloride-dependent conformational changes in the GlyT1 glycine transporter
Yuan-Wei Zhang, Stacy Uchendu, Vanessa Leone, Richard T. Bradshaw, Ntumba Sangwa, Lucy R. Forrest, Gary Rudnick
Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2017431118. Published online 2021 Mar 3. doi: 10.1073/pnas.2017431118
PMCID:
PMC7958241
AbstractArticlePDF–1.4M
4.
Do damaging variants of SLC6A9, the gene for the glycine transporter 1 (GlyT-1), protect against schizophrenia?
David Curtis
Psychiatr Genet. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Psychiatr Genet. 2020 Oct; 30(5): 150–152. doi: 10.1097/YPG.0000000000000260
PMCID:
PMC7882767
AbstractArticlePDF–57K
5.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
6.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
7.
Blood-Brain Barrier: From Physiology to Disease and Back
Melanie D. Sweeney, Zhen Zhao, Axel Montagne, Amy R. Nelson, Berislav V. Zlokovic
Physiol Rev. 2019 Jan 1; 99(1): 21–78. Published online 2018 Oct 3. doi: 10.1152/physrev.00050.2017
PMCID:
PMC6335099
AbstractArticle
8.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
9.
Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability
Hema Adhikari, Christopher M. Counter
Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6
PMCID:
PMC6128905
AbstractArticlePDF–2.2M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Loss of Glycine Transporter 1 Causes a Subtype of Glycine Encephalopathy with Arthrogryposis and Mildly Elevated Cerebrospinal Fluid Glycine
Alina Kurolap, Anja Armbruster, Tova Hershkovitz, Katharina Hauf, Adi Mory, Tamar Paperna, Ewald Hannappel, Galit Tal, Yusif Nijem, Ella Sella, Muhammad Mahajnah, Anat Ilivitzki, Dov Hershkovitz, Nina Ekhilevitch, Hanna Mandel, Volker Eulenburg, Hagit N. Baris
Am J Hum Genet. 2016 Nov 3; 99(5): 1172–1180. Published online 2016 Oct 20. doi: 10.1016/j.ajhg.2016.09.004
PMCID:
PMC5097939
AbstractArticlePDF–1.0M
12.
A dynamic protein interaction landscape of the human centrosome-cilium interface
Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier
Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065
PMCID:
PMC5089374
AbstractArticlePDF–1.5M
13.
Mutation in SLC6A9 encoding a glycine transporter causes a novel form of non-ketotic hyperglycinemia in humans
Majid Alfadhel, Marwan Nashabat, Hanan Al Qahtani, Ahmed Alfares, Fuad Al Mutairi, Hesham Al Shaalan, Ganka V. Douglas, Klaas Wierenga, Jane Juusola, Muhammad Talal Alrifai, Stefan T. Arold, Fowzan Alkuraya, Qais Abu Ali
Hum Genet. 2016; 135(11): 1263–1268. Published online 2016 Aug 1. doi: 10.1007/s00439-016-1719-x
PMCID:
PMC5052303
AbstractArticlePDF–702K
14.
Establishment and Dysfunction of the Blood-Brain Barrier
Zhen Zhao, Amy R. Nelson, Christer Betsholtz, Berislav V. Zlokovic
Cell. Author manuscript; available in PMC 2016 Nov 19.
Published in final edited form as: Cell. 2015 Nov 19; 163(5): 1064–1078. doi: 10.1016/j.cell.2015.10.067
PMCID:
PMC4655822
AbstractArticlePDF–1.4M
15.
Glycine Transporter 1 is a Target for the Treatment of Epilepsy
Hai-Ying Shen, Erwin van Vliet, Kerry-Ann Bright, Marissa Hanthorn, Nikki Lytle, Jan Gorter, Eleonora Aronica, Detlev Boison
Neuropharmacology. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: Neuropharmacology. 2015 Dec; 99: 554–565. Published online 2015 Aug 21. doi: 10.1016/j.neuropharm.2015.08.031
PMCID:
PMC4655139
AbstractArticlePDF–1.3M
16.
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families
Manav Kapoor, Jen-Chyong Wang, Leah Wetherill, Nhung Le, Sarah Bertelsen, Anthony L Hinrichs, John Budde, Arpana Agrawal, Laura Almasy, Kathleen Bucholz, Danielle M Dick, Oscar Harari, Xuei Xiaoling, Victor Hesselbrock, John Kramer, John I Nurnberger, Jr, John Rice, Marc Schuckit, Jay Tischfield, Bernice Porjesz, Howard J Edenberg, Laura Bierut, Tatiana Foroud, Alison Goate
Drug Alcohol Depend. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Drug Alcohol Depend. 2014 Sep 1; 142: 56–62. Published online 2014 Jun 11. doi: 10.1016/j.drugalcdep.2014.05.023
PMCID:
PMC4127128
AbstractArticlePDF–598K
17.
Glycine Transporter Type 1 Occupancy by Bitopertin: a Positron Emission Tomography Study in Healthy Volunteers
Meret Martin-Facklam, Flavia Pizzagalli, Yun Zhou, Susanne Ostrowitzki, Vanessa Raymont, James R Brašić, Nikhat Parkar, Daniel Umbricht, Robert F Dannals, Ron Goldwater, Dean F Wong
Neuropsychopharmacology. 2013 Feb; 38(3): 504–512. Published online 2012 Nov 7. doi: 10.1038/npp.2012.212
PMCID:
PMC3547202
AbstractArticlePDF–505K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia
Xiangdong Deng, Noriaki Sagata, Naoko Takeuchi, Masami Tanaka, Hideaki Ninomiya, Nakao Iwata, Norio Ozaki, Hiroki Shibata, Yasuyuki Fukumaki
BMC Psychiatry. 2008; 8: 58. Published online 2008 Jul 18. doi: 10.1186/1471-244X-8-58
PMCID:
PMC2491607
AbstractArticlePDF–388K
20.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K

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