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Select item 102394111.

Downregulated INHBB in endometrial tissue of recurrent implantation failure patients impeded decidualization through the ADCY1/cAMP signalling pathway

Hui Zhang, Zhilong Wang, Quan Zhou, Zhiwen Cao, Yue Jiang, Manlin Xu, Jingyu Liu, Jidong Zhou, Guijun Yan, Haixiang Sun

J Assist Reprod Genet. 2023 May; 40(5): 1135–1146. Published online 2023 Mar 13. doi: 10.1007/s10815-023-02762-7

PMCID:: PMC10239411

Abstract Article PDF–5.4M

Select item 85169282.

GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses

Youfu Zhang, Jinran Yang, Xuyang Wang, Xinchang Li

Sci Rep. 2021; 11: 20441. Published online 2021 Oct 14. doi: 10.1038/s41598-021-99544-x

PMCID:: PMC8516928

Abstract Article PDF–2.8M

Select item 84167313.

Pancreatic cancer-derived exosomal microRNA-19a induces β-cell dysfunction by targeting ADCY1 and EPAC2

Wenjing Pang, Weiyan Yao, Xin Dai, Aisen Zhang, Lidan Hou, Lei Wang, Yu Wang, Xin Huang, Xiangjun Meng, Lei Li

Int J Biol Sci. 2021; 17(13): 3622–3633. Published online 2021 Aug 21. doi: 10.7150/ijbs.56271

PMCID:: PMC8416731

Abstract Article PDF–2.0M

Select item 64013964.

MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways

Meng Ma, Jie Dai, Huan Tang, Tianxiao Xu, Sifan Yu, Lu Si, Chuanliang Cui, Xinan Sheng, Zhihong Chi, Lili Mao, Xiaowen Wu, Lu Yang, Huan Yu, Siming Li, Bin Lian, Bixiang Tang, Xuan Wang, Xieqiao Yan, Xue Bai, Li Zhou, Yan Kong, Jun Guo

Theranostics. 2019; 9(4): 945–960. Published online 2019 Jan 25. doi: 10.7150/thno.30516

Correction in:: Theranostics. 2022; 12(7): 3578–3579.

PMCID:: PMC6401396

Abstract Article PDF–3.6M

Select item 57346335.

Identification of a selective small molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Tarsis F. Brust, Doungkamol Alongkronrusmee, Monica Soto-Velasquez, Tanya A. Baldwin, Zhishi Ye, Mingji Dai, Carmen W. Dessauer, Richard M. van Rijn, Val J. Watts

Sci Signal. Author manuscript; available in PMC 2017 Dec 18.

Published in final edited form as: Sci Signal. 2017 Feb 21; 10(467): eaah5381. Published online 2017 Feb 21. doi: 10.1126/scisignal.aah5381

PMCID:: PMC5734633

Abstract Article PDF–1.6M

Select item 55035126.

The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms

Wenbao Hu, Xiaojie Yu, Zhengzhao Liu, Ying Sun, Xibing Chen, Xin Yang, Xiaofen Li, Wai Kwan Lam, Yuanyuan Duan, Xu Cao, Hermann Steller, Kai Liu, Pingbo Huang

eLife. 2017; 6: e28021. Published online 2017 Jun 28. doi: 10.7554/eLife.28021

PMCID:: PMC5503512

Abstract Article PDF–6.6M

Select item 54952257.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 54066098.

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor

Yuki Shikata, Tetsuro Yoshimaru, Masato Komatsu, Hiroto Katoh, Reiko Sato, Shuhei Kanagaki, Yasumasa Okazaki, Shinya Toyokuni, Etsu Tashiro, Shumpei Ishikawa, Toyomasa Katagiri, Masaya Imoto

Cancer Sci. 2017 Apr; 108(4): 785–794. Published online 2017 Apr 20. doi: 10.1111/cas.13175

PMCID:: PMC5406609

Abstract Article PDF–1.3M

Select item 53717309.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 455434510.

HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorders

Thangavel Samikkannu, Venkata S.R. Atluri, Adriana Y. Arias, Kesava V.K. Rao, Carmen T. Mulet, Rahul D. Jayant, Madhavan P.N. Nair

Curr HIV Res. Author manuscript; available in PMC 2015 Aug 31.

Published in final edited form as: Curr HIV Res. 2014; 12(6): 397–405. doi: 10.2174/1570162x13666150121104720

PMCID:: PMC4554345

Abstract Article PDF–1.5M

Select item 428715211.

Overexpression of the Type 1 Adenylyl Cyclase in the Forebrain Leads to Deficits of Behavioral Inhibition

Xuanmao Chen, Hong Cao, Amit Saraf, Larry S. Zweifel, Daniel R. Storm

J Neurosci. 2015 Jan 7; 35(1): 339–351. doi: 10.1523/JNEUROSCI.2478-14.2015

PMCID:: PMC4287152

Abstract Article PDF–3.6M

Select item 403078212.

Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish

Regie Lyn P. Santos-Cortez, Kwanghyuk Lee, Arnaud P. Giese, Muhammad Ansar, Muhammad Amin-Ud-Din, Kira Rehn, Xin Wang, Abdul Aziz, Ilene Chiu, Raja Hussain Ali, Joshua D. Smith, University of Washington Center for Mendelian Genomics, Jay Shendure, Michael Bamshad, Deborah A. Nickerson, Zubair M. Ahmed, Wasim Ahmad, Saima Riazuddin, Suzanne M. Leal

Hum Mol Genet. 2014 Jun 15; 23(12): 3289–3298. Published online 2014 Jan 29. doi: 10.1093/hmg/ddu042

PMCID:: PMC4030782

Abstract Article PDF–1.5M

Select item 362881813.

Differential effects of AGS3 expression on D_2L dopamine receptor-mediated adenylyl cyclase signaling

Jason M. Conley, Val J. Watts

Cell Mol Neurobiol. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Cell Mol Neurobiol. 2013 May; 33(4): 551–558. Published online 2013 Mar 17. doi: 10.1007/s10571-013-9925-8

PMCID:: PMC3628818

Article PDF–366K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298649915.

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis

Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein

Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264

PMCID:: PMC2986499

Abstract Article PDF–172K

Select item 292013816.

DFNB44, a Novel Autosomal Recessive Non-Syndromic Hearing Impairment Locus, Maps to Chromosome 7p14.1-q11.22

Muhammad Ansar, Maria H. Chahrour, Mohammad Amin ud Din, Muhammad Arshad, Sayedul Haque, Thanh L. Pham, Kai Yan, Wasim Ahmad, Suzanne M. Leal

Hum Hered. Author manuscript; available in PMC 2010 Aug 11.

Published in final edited form as: Hum Hered. 2004; 57(4): 195–199. doi: 10.1159/000081446

PMCID:: PMC2920138

Abstract Article PDF–617K

Select item 291235017.

CFTR-Adenylyl Cyclase I Association Responsible for UTP Activation of CFTR in Well-Differentiated Primary Human Bronchial Cell Cultures

Wan Namkung, Walter E. Finkbeiner, A. S. Verkman

Mol Biol Cell. 2010 Aug 1; 21(15): 2639–2648. doi: 10.1091/mbc.E09-12-1004

PMCID:: PMC2912350

Abstract Article PDF–2.2M

Select item 288296118.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 275741519.

Overexpression of Type I Adenylyl Cyclase in the Forebrain Impairs Spatial Memory in Aged But Not Young Mice

Michael G. Garelick, Guy C. K. Chan, Derek P. DiRocco, Daniel R. Storm

J Neurosci. 2009 Sep 2; 29(35): 10835–10842. doi: 10.1523/JNEUROSCI.0553-09.2009

PMCID:: PMC2757415

Abstract Article PDF–711K

Select item 275281120.

Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging

Heather E. Wheeler, E. Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M. Zahn, Julie Wilhelmy, Ronald W. Davis, Andrew Singleton, Richard M. Myers, Luigi Ferrucci, Stuart K. Kim

PLoS Genet. 2009 Oct; 5(10): e1000685. Published online 2009 Oct 16. doi: 10.1371/journal.pgen.1000685

PMCID:: PMC2752811

Abstract Article PDF–409K

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