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Select item 110016401.

Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB–dependent IFITM3 expression

Moiz Munir, Aaron Embry, John G. Doench, Nicholas S. Heaton, Craig B. Wilen, Robert C. Orchard

J Biol Chem. 2024 Apr; 300(4): 107153. Published online 2024 Mar 9. doi: 10.1016/j.jbc.2024.107153

PMCID:: PMC11001640

Abstract Article PDF–3.7M

Select item 108915182.

Inflammatory Polymorphisms (IL-6 rs1800796, IL-10 rs1800896, TNF-α rs1800629, and IFITM3 rs12252) Are Not Associated with Post-COVID Symptoms in Previously Hospitalized COVID-19 Survivors

César Fernández-de-las-Peñas, Gema Díaz-Gil, Antonio Gil-Crujera, Stella M. Gómez-Sánchez, Silvia Ambite-Quesada, Juan Torres-Macho, Pablo Ryan-Murua, Ana I. Franco-Moreno, Oscar J. Pellicer-Valero, Lars Arendt-Nielsen, Rocco Giordano

Viruses. 2024 Feb; 16(2): 275. Published online 2024 Feb 9. doi: 10.3390/v16020275

PMCID:: PMC10891518

Abstract Article PDF–275K

Select item 107895403.

IFITM3-mediated activation of TRAF6/MAPK/AP-1 pathways induces acquired TKI resistance in clear cell renal cell carcinoma

Se Un Jeong, Ja-Min Park, Sun Young Yoon, Hee Sang Hwang, Heounjeong Go, Dong-Myung Shin, Hyein Ju, Chang Ohk Sung, Jae-Lyun Lee, Gowun Jeong, Yong Mee Cho

Investig Clin Urol. 2024 Jan; 65(1): 84–93. Published online 2023 Dec 28. doi: 10.4111/icu.20230294

PMCID:: PMC10789540

Abstract Article PDF–15M

Select item 107788864.

A Knockout of the IFITM3 Gene Increases the Sensitivity of WI-38 VA13 Cells to the Influenza A Virus

Natalya Eshchenko, Mariia Sergeeva, Evgenii Zhuravlev, Kira Kudria, Elena Goncharova, Andrey Komissarov, Grigory Stepanov

Int J Mol Sci. 2024 Jan; 25(1): 625. Published online 2024 Jan 3. doi: 10.3390/ijms25010625

PMCID:: PMC10778886

Abstract Article PDF–7.2M

Select item 107483745.

IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters

Smita Verma, Yen-Cheng Chen, Mariana Marin, Scott E. Gillespie, Gregory B. Melikyan

Viruses. 2023 Dec; 15(12): 2390. Published online 2023 Dec 7. doi: 10.3390/v15122390

PMCID:: PMC10748374

Abstract Article PDF–2.9M

Select item 102903706.

Interferon-induced transmembrane protein 3 in hepatocellular carcinoma patients

Rania M. Bondok, Lamiaa A. Barakat, Alyaa R. Elsergany, Nancy Mahsoub, Maivel H. Ghattas

BMC Cancer. 2023; 23: 584. Published online 2023 Jun 23. doi: 10.1186/s12885-023-11071-2

PMCID:: PMC10290370

Abstract Article PDF–870K

Select item 101838207.

Interferon‐inducible phospholipids govern IFITM3‐dependent endosomal antiviral immunity

Giulia Unali, Giovanni Crivicich, Isabel Pagani, Monah Abou‐Alezz, Filippo Folchini, Erika Valeri, Vittoria Matafora, Julie A Reisz, Anna Maria Sole Giordano, Ivan Cuccovillo, Giacomo M Butta, Lorena Donnici, Angelo D'Alessandro, Raffaele De Francesco, Lara Manganaro, Davide Cittaro, Ivan Merelli, Carolina Petrillo, Angela Bachi, Elisa Vicenzi, Anna Kajaste‐Rudnitski

EMBO J. 2023 May; 42(10): e112234. Published online 2023 Mar 27. doi: 10.15252/embj.2022112234

PMCID:: PMC10183820

Abstract Article PDF–7.3M

Select item 101015428.

Genetic polymorphisms of ACE1, ACE2, IFTM3, TMPRSS2 and TNFα genes associated with susceptibility and severity of SARS-CoV-2 infection: a systematic review and meta-analysis

Valentina Pecoraro, Michela Cuccorese, Tommaso Trenti

Clin Exp Med. 2023 Apr 13 : 1–14. doi: 10.1007/s10238-023-01038-9 [Epub ahead of print]

PMCID:: PMC10101542

Abstract Article PDF–1.2M

Select item 98134329.

Does IFITM3 link inflammation to tumorigenesis?

Jaewoong Lee

BMB Rep. 2022 Dec 31; 55(12): 602–608. Published online 2022 Dec 31. doi: 10.5483/BMBRep.2022.55.12.161

PMCID:: PMC9813432

Abstract Article PDF–2.8M

Select item 969236710.

IFITM3 Inhibits SARS-CoV-2 Infection and Is Associated with COVID-19 Susceptibility

Fengwen Xu, Geng Wang, Fei Zhao, Yu Huang, Zhangling Fan, Shan Mei, Yu Xie, Liang Wei, Yamei Hu, Conghui Wang, Shan Cen, Chen Liang, Lili Ren, Fei Guo, Jianwei Wang

Viruses. 2022 Nov; 14(11): 2553. Published online 2022 Nov 18. doi: 10.3390/v14112553

PMCID:: PMC9692367

Abstract Article PDF–2.6M

Select item 967595111.

Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant

Melika Gholami, Fatemeh Sakhaee, Fattah Sotoodehnejadnematalahi, Mohammad Saber Zamani, Iraj Ahmadi, Enayat Anvari, Abolfazl Fateh

Hum Genomics. 2022; 16: 60. Published online 2022 Nov 19. doi: 10.1186/s40246-022-00434-8

PMCID:: PMC9675951

Abstract Article PDF–941K

Select item 960112112.

The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation

Khurts Shilagardi, Eric D. Spear, Rachy Abraham, Diane E. Griffin, Susan Michaelis

mBio. 2022 Sep-Oct; 13(5): e02543-22. Published online 2022 Oct 5. doi: 10.1128/mbio.02543-22

PMCID:: PMC9601121

Abstract Article PDF–1.4M

Select item 958186513.

MiR-487b suppressed inflammation and neuronal apoptosis in spinal cord injury by targeted Ifitm3

Dake Tong, Yanyin Zhao, Yang Tang, Jie Ma, Miao Wang, Bo Li, Zhiwei Wang, Cheng Li

Metab Brain Dis. 2022; 37(7): 2405–2415. Published online 2022 Jul 8. doi: 10.1007/s11011-022-01015-3

PMCID:: PMC9581865

Abstract Article PDF–2.5M

Select item 942277914.

Differential Leukocyte Expression of IFITM1 and IFITM3 in Patients with Severe Pandemic Influenza A(H1N1) and COVID-19

Nora E. Regino-Zamarripa, Gustavo Ramírez-Martínez, Luis Armando Jiménez-Álvarez, Alfredo Cruz-Lagunas, Itzel Alejandra Gómez-García, Sergio Ignacio-Cortés, José Eduardo Márquez-García, Lynette Miroslava Pacheco-Hernández, Jazmín Ariadna Ramírez-Noyola, Rodrigo Barquera, Criselda Mendoza-Milla, Cesar Luna-Rivero, José Guillermo Domínguez-Cherit, Remedios Ramírez-Rangel, Tatiana Sofía Rodríguez-Reyna, Carmen M. Hernández-Cárdenas, José Alberto Choreño-Parra, Gloria León-Ávila, Joaquín Zúñiga

J Interferon Cytokine Res. August 2022; 42(8): 430–443. Published online 2022 Aug 18. doi: 10.1089/jir.2022.0036

PMCID:: PMC9422779

Abstract Article PDF–1.1M

Select item 940560115.

Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer

Maria Gómez-Herranz, Jakub Faktor, Marcos Yébenes Mayordomo, Magdalena Pilch, Marta Nekulova, Lenka Hernychova, Kathryn L. Ball, Borivoj Vojtesek, Ted R. Hupp, Sachin Kote

Biomolecules. 2022 Aug; 12(8): 1090. Published online 2022 Aug 8. doi: 10.3390/biom12081090

PMCID:: PMC9405601

Abstract Article PDF–2.8M

Select item 925029016.

Impact of interferon-induced transmembrane protein 3 gene rs12252 polymorphism on COVID-19 mortality

Iraj Ahmadi, Alireza Afifipour, Fatemeh Sakhaee, Mohammad Saber Zamani, Fahimeh Mirzaei Gheinari, Enayat Anvari, Abolfazl Fateh

Cytokine. 2022 Sep; 157: 155957. Published online 2022 Jul 2. doi: 10.1016/j.cyto.2022.155957

PMCID:: PMC9250290

Abstract Article PDF–575K

Select item 923162317.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 915104618.

IFITM3 rs12252 T>C polymorphism is associated with the risk of severe influenza: a meta-analysis

Y. XUAN, L. N. WANG, W. LI, H. R. ZI, Y. GUO, W. J. YAN, X. B. CHEN, P. M. WEI

Epidemiol Infect. 2015 Oct; 143(14): 2975–2984. Published online 2015 Mar 17. doi: 10.1017/S0950268815000278

PMCID:: PMC9151046

Abstract Article PDF–355K

Select item 902762119.

IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection

Massimo Palatini, Simon Franz Müller, Michael Kirstgen, Silke Leiting, Felix Lehmann, Lena Soppa, Nora Goldmann, Christin Müller, Kira Alessandra Alicia Theresa Lowjaga, Jörg Alber, Giuliano Ciarimboli, John Ziebuhr, Dieter Glebe, Joachim Geyer

Viruses. 2022 Apr; 14(4): 727. Published online 2022 Mar 30. doi: 10.3390/v14040727

PMCID:: PMC9027621

Abstract Article PDF–1.6M

Select item 877895820.

No Association between Single Nucleotide Polymorphisms (SNPs) of the Interferon-Induced Transmembrane Protein 3 (IFITM3) Gene and the Susceptibility of Alzheimer’s Disease (AD)

Sae-Young Won, Yong-Chan Kim, Byung-Hoon Jeong

Medicina (Kaunas) 2022 Jan; 58(1): 55. Published online 2021 Dec 30. doi: 10.3390/medicina58010055

PMCID:: PMC8778958

Abstract Article PDF–640K

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