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Select item 110066981.

高表达UBE2S通过增加癌细胞干性促进肝癌的进程机制

陈浩, 李振汉, 王明婷, 卢林明, 唐乾利, 罗良平

Nan Fang Yi Ke Da Xue Xue Bao. 2024 Mar 20; 44(3): 455–464. Chinese. doi: 10.12122/j.issn.1673-4254.2024.03.06

PMCID:: PMC11006698

Abstract Article PDF–4.7M

Select item 108508182.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 103296823.

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

Kanghua Xiao, Shengmeng Peng, Junlin Lu, Ting Zhou, Xuwei Hong, Siting Chen, Guangyao Liu, Hong Li, Jian Huang, Xu Chen, Tianxin Lin

Cell Death Dis. 2023 Jul; 14(7): 408. Published online 2023 Jul 8. doi: 10.1038/s41419-023-05938-2

PMCID:: PMC10329682

Abstract Article PDF–20M

Select item 102485544.

The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity

Sahezeel Awadia, Merna Sitto, Sundaresh Ram, Wenbin Ji, Yajing Liu, Raheema Damani, Dipankar Ray, Theodore S. Lawrence, Craig J. Galban, Steven D. Cappell, Alnawaz Rehemtulla

J Biol Chem. 2023 Jun; 299(6): 104786. Published online 2023 May 4. doi: 10.1016/j.jbc.2023.104786

PMCID:: PMC10248554

Abstract Article PDF–6.8M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91665997.

UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis

Mengjun Zhang, Yuan Liu, Yue Yin, Zhenxing Sun, Yan Wang, Zexue Zhang, Fei Li, Xiuwei Chen

Mol Med. 2022; 28: 62. Published online 2022 Jun 3. doi: 10.1186/s10020-022-00489-2

PMCID:: PMC9166599

Abstract Article PDF–15M

Select item 91349228.

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer

Shengmeng Peng, Xu Chen, Chaoyun Huang, Chenwei Yang, Minyi Situ, Qianghua Zhou, Yihong Ling, Hao Huang, Ming Huang, Yangjie Zhang, Liang Cheng, Qiang Zhang, Zhenghui Guo, Yiming Lai, Jian Huang

Int J Biol Sci. 2022; 18(8): 3528–3543. Published online 2022 May 16. doi: 10.7150/ijbs.72629

PMCID:: PMC9134922

Abstract Article PDF–5.7M

Select item 91123499.

Examining the mechanistic relationship of APC/C^CDH1 and its interphase inhibitor EMI1

Derek L. Bolhuis, Raquel C. Martinez‐Chacin, Kaeli A. Welsh, Tatyana Bodrug, Liying Cui, Michael J. Emanuele, Nicholas G. Brown

Protein Sci. 2022 Jun; 31(6): e4324. Published online 2022 May 17. doi: 10.1002/pro.4324

PMCID:: PMC9112349

Abstract Article PDF–4.2M

Select item 902051710.

Structural and functional consequences of NEDD8 phosphorylation

Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner

Nat Commun. 2021; 12: 5939. Published online 2021 Oct 12. doi: 10.1038/s41467-021-26189-9

PMCID:: PMC9020517

Abstract Article PDF–2.8M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 880493312.

Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes

Kaeli A Welsh, Derek L Bolhuis, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown

EMBO J. 2022 Feb 1; 41(3): e108823. Published online 2021 Dec 23. doi: 10.15252/embj.2021108823

PMCID:: PMC8804933

Abstract Article PDF–3.8M

Select item 876007713.

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord

Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6

PMCID:: PMC8760077

Abstract Article PDF–12M

Select item 874173914.

APC7 Mediates Ubiquitin Signaling in Constitutive Heterochromatin in the Developing Mammalian Brain

Cole J. Ferguson, Olivia Urso, Tatyana Bodrug, Brandon M. Gassaway, Edmond R. Watson, Jesuraj R. Prabu, Pablo Lara-Gonzalez, Raquel C. Martinez-Chacin, Dennis Y. Wu, Karlla W. Brigatti, Erik G. Puffenberger, Cora M. Taylor, Barbara Haas-Givler, Robert N. Jinks, Kevin A. Strauss, Arshad Desai, Harrison W. Gabel, Steven P. Gygi, Brenda A. Schulman, Nicholas G. Brown, Azad Bonni

Mol Cell. Author manuscript; available in PMC 2023 Jan 6.

Published in final edited form as: Mol Cell. 2022 Jan 6; 82(1): 90–105.e13. Published online 2021 Dec 22. doi: 10.1016/j.molcel.2021.11.031

PMCID:: PMC8741739

Abstract Article PDF–4.4M

Select item 859565915.

UBE2S promotes cell chemoresistance through PTEN-AKT signaling in hepatocellular carcinoma

Liang Gui, Sicai Zhang, Yongzi Xu, Hongwei Zhang, Ying Zhu, Lianbao Kong

Cell Death Discov. 2021; 7: 357. Published online 2021 Nov 16. doi: 10.1038/s41420-021-00750-3

PMCID:: PMC8595659

Abstract Article PDF–5.9M

Select item 855290716.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 844771717.

UBE2S promotes the progression and Olaparib resistance of ovarian cancer through Wnt/β-catenin signaling pathway

Wenjing Hu, Min Li, Youguo Chen, Xinxian Gu

J Ovarian Res. 2021; 14: 121. Published online 2021 Sep 17. doi: 10.1186/s13048-021-00877-y

PMCID:: PMC8447717

Abstract Article PDF–12M

Select item 835296418.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 797970520.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

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PMC Links for GEO Profiles (Select 18825156) (104)
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tetratricopeptide repeat protein [Pelagicoccus albus]
tetratricopeptide repeat protein [Pelagicoccus albus]
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