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Select item 111157841.

ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity

J. Dubail, F. Kesteloot, C. Deroanne, P. Motte, V. Lambert, J.-M. Rakic, C. Lapière, B. Nusgens, A. Colige

Cell Mol Life Sci. 2010 Dec; 67(24): 4213–4232. Published online 2010 Jun 24. doi: 10.1007/s00018-010-0431-6

PMCID:: PMC11115784

Abstract Article PDF–2.9M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109530993.

Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function

Edward P Carter, Kubra K Yoneten, Nuria Gavara, Eleanor J Tyler, Valentine Gauthier, Elizabeth R Murray, Peter ten Dijke, Angus J Cameron, Oliver Pearce, Richard P Grose

J Pathol. 2024 Jan; 262(1): 90–104. Published online 2023 Nov 6. doi: 10.1002/path.6214

PMCID:: PMC10953099

Abstract Article PDF–16M

Select item 107310254.

Tollip deficiency exaggerates airway type 2 inflammation in mice exposed to allergen and influenza A virus: role of the ATP/IL-33 signaling axis

Hamid Reza Nouri, Niccolette Schaunaman, Monica Kraft, Liwu Li, Mari Numata, Hong Wei Chu

Front Immunol. 2023; 14: 1304758. Published online 2023 Dec 6. doi: 10.3389/fimmu.2023.1304758

PMCID:: PMC10731025

Abstract Article PDF–10M

Select item 102834405.

Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules

Cuiwei Yang, Zhangshun Wang, Yingjin Kang, Qianqian Yi, Tong Wang, Yun Bai, Yanfen Liu

Autophagy. 2023; 19(7): 1934–1951. Published online 2023 Jan 24. doi: 10.1080/15548627.2022.2164427

PMCID:: PMC10283440

Abstract Article PDF–5.2M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101551957.

Genome-wide association study of early ischemic stroke risk in Brazilian Individuals with Sickle Cell Disease implicates ADAMTS2, CDK18 and uncovers novel loci

Eric Jay Earley, Shannon Kelly, Fang Fang, Cecília Salete Alencar, Daniela de Oliveira Werneck Rodrigues, Dahra Teles Soares Cruz, Jonathan M. Flanagan, Russell E. Ware, Xu Zhang, Victor Gordeuk, Mark Gladwin, Yingze Zhang, Mehdi Nouraie, Sergei Nekhai, Ester Sabino, Brian Custer, Carla Dinardo, Grier P. Page

Br J Haematol. Author manuscript; available in PMC 2023 May 3.

Published in final edited form as: Br J Haematol. 2023 Apr; 201(2): 343–352. Published online 2023 Jan 5. doi: 10.1111/bjh.18637

PMCID:: PMC10155195

Abstract Article PDF–426K

Select item 100129578.

NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2)

Jiawei Hao, Jinqian Li, Zhenzhen Zhang, Yang Yang, Qing Zhou, Tiantian Wu, Tongling Chen, Zhongdao Wu, Ping Zhang, Jun Cui, Yi-Ping Li

Autophagy. 2023; 19(4): 1332–1347. Published online 2022 Sep 29. doi: 10.1080/15548627.2022.2126614

PMCID:: PMC10012957

Abstract Article PDF–3.8M

Select item 97414079.

TOLLIP Protein Expression Predicts Unfavorable Outcome in Renal Cell Carcinoma

Adam Kowalewski, Damian Jaworski, Jędrzej Borowczak, Mateusz Maniewski, Krzysztof Szczerbowski, Paulina Antosik, Justyna Durślewicz, Marta Smolińska, Joanna Ligmanowska, Dariusz Grzanka, Łukasz Szylberg

Int J Mol Sci. 2022 Dec; 23(23): 14702. Published online 2022 Nov 25. doi: 10.3390/ijms232314702

PMCID:: PMC9741407

Abstract Article PDF–2.6M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 944065311.

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui

Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y

PMCID:: PMC9440653

Abstract Article PDF–2.9M

Select item 934857612.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 933949613.

TOLLIP optimizes dendritic cell maturation to LPS and Mycobacterium tuberculosis

Sambasivan Venkatasubramanian, Robyn Pryor, Courtney Plumlee, Sarah B. Cohen, Jason D. Simmons, Alexander J. Warr, Andrew D. Graustein, Aparajita Saha, Thomas R. Hawn, Kevin B. Urdahl, Javeed A. Shah

J Immunol. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: J Immunol. 2022 Aug 1; 209(3): 435–445. Published online 2022 Jul 8. doi: 10.4049/jimmunol.2200030

PMCID:: PMC9339496

Abstract Article PDF–1.3M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 897359515.

Somatostatin attenuates intestinal epithelial barrier injury during acute intestinal ischemia–reperfusion through Tollip/Myeloiddifferentiationfactor 88/Nuclear factor kappa-B signaling

Yan Tian, Ruo Shu, Yi Lei, Yu Xu, Xinfeng Zhang, Huayou Luo

Bioengineered. 2022; 13(3): 5005–5020. Published online 2022 Feb 14. doi: 10.1080/21655979.2022.2038450

PMCID:: PMC8973595

Abstract Article PDF–4.0M

Select item 885704916.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 874895817.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 856647318.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 855290719.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 852592420.

RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis

Huazhi Zhang, Zhihui Cui, Du Cheng, Yanyun Du, Xiaoli Guo, Ru Gao, Jianwen Chen, Wanwei Sun, Ruirui He, Xiaojian Ma, Qianwen Peng, Bradley N. Martin, Wei Yan, Yueguang Rong, Chenhui Wang

Autophagy. 2021; 17(10): 3030–3047. Published online 2020 Dec 17. doi: 10.1080/15548627.2020.1851496

PMCID:: PMC8525924

Abstract Article PDF–18M

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