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Select item 109646161.

Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax

Danyang Li, Yigang Yuan, Chen Meng, Zihan Lin, Min Zhao, Liuzhi Shi, Min Li, Daijiao Ye, Yue Cai, Xiaofei He, Haige Ye, Shujuan Zhou, Haixia Zhou, Shenmeng Gao

Clin Epigenetics. 2024; 16: 48. Published online 2024 Mar 26. doi: 10.1186/s13148-024-01658-2

PMCID:: PMC10964616

Abstract Article PDF–2.4M

Select item 108492732.

PBX3 as a biomarker for the early diagnosis and prediction of prognosis of glioma

Cuicui pan, Xueli bai, Na Li, Ni Zheng, Yuanquan Si, Yueran Zhao

PLoS One. 2024; 19(2): e0293647. Published online 2024 Feb 7. doi: 10.1371/journal.pone.0293647

PMCID:: PMC10849273

Abstract Article PDF–2.9M

Select item 100339373.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 89904625.

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling

Dandan Wang, Xiaoying Jin, Mengxia Lei, Ying Jiang, Yali Liu, Fei Yu, Yan Guo, Bing Han, Yue Yang, Weiling Sun, Ying Liu, Guangchun Zeng, Feng Liu, Jing Hu, Xuesong Chen

Int J Biol Sci. 2022; 18(6): 2452–2471. Published online 2022 Mar 14. doi: 10.7150/ijbs.69134

PMCID:: PMC8990462

Abstract Article PDF–3.8M

Select item 89735906.

Long non-coding RNA DSCAM-AS1 promotes pancreatic cancer progression via regulating the miR-136-5p/PBX3 axis

Xing Huang, Zihe Wang, Shengzhong Hou, Chao Yue, ZhenLu Li, Weiming Hu, Huimin Lu

Bioengineered. 2022; 13(2): 4153–4165. Published online 2022 Feb 10. doi: 10.1080/21655979.2021.2016326

PMCID:: PMC8973590

Abstract Article PDF–4.4M

Select item 89230577.

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava

Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021

PMCID:: PMC8923057

Abstract Article PDF–2.5M

Select item 88421658.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 87489589.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 856452410.

The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the tumor suppressor p53

Wen-fang Li, Arin Herkilini, Yu Tang, Ping Huang, Guan-bin Song, Makoto Miyagishi, Vivi Kasim, Shou-rong Wu

Acta Pharmacol Sin. 2021 Nov; 42(11): 1888–1899. Published online 2021 Feb 1. doi: 10.1038/s41401-020-00599-9

PMCID:: PMC8564524

Abstract Article PDF–4.4M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 700775113.

PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma

Qin Chen, Wen-Ying Yu, Huan-Huan Zhang, Song-Zhao Zhang, Jie Fang, Fang Wu, Hua-Zhong Ying, Chen-Huan Yu

Biomed Res Int. 2020; 2020: 8954513. Published online 2020 Jan 25. doi: 10.1155/2020/8954513

PMCID:: PMC7007751

Abstract Article PDF–1.0M

Select item 674256614.

Cutaneous Syncytial Myoepithelioma is Characterized by Recurrent EWSR1-PBX3 Fusions

Vickie Y. Jo, Cristina R. Antonescu, Brendan C. Dickson, David Swanson, Lei Zhang, Christopher D.M. Fletcher, Elizabeth G. Demicco

Am J Surg Pathol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Am J Surg Pathol. 2019 Oct; 43(10): 1349–1354. doi: 10.1097/PAS.0000000000001286

PMCID:: PMC6742566

Abstract Article PDF–428K

Select item 663917515.

PBX3 hypermethylation in peripheral blood leukocytes predicts better prognosis in colorectal cancer: A propensity score analysis

Hongru Sun, Hao Huang, Dapeng Li, Lei Zhang, Yuanyuan Zhang, Jing Xu, Ying Liu, Yupeng Liu, Yashuang Zhao

Cancer Med. 2019 Jul; 8(8): 4001–4011. Published online 2019 May 29. doi: 10.1002/cam4.2321

PMCID:: PMC6639175

Abstract Article PDF–292K

Select item 637596416.

miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3

Meng Wang, Guoyue Lv, Chao Jiang, Shuli Xie, Guangyi Wang

Sci Rep. 2019; 9: 2032. Published online 2019 Feb 14. doi: 10.1038/s41598-018-38435-0

PMCID:: PMC6375964

Abstract Article PDF–2.5M

Select item 613492817.

Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival

Wu Zhang, Chen Zhao, Junmei Zhao, Yongmei Zhu, Xiangqin Weng, Qiusheng Chen, Huiping Sun, Jian-Qing Mi, Junmin Li, Jiang Zhu, Zhu Chen, Pier Paolo Pandolfi, Saijuan Chen, Xiaojing Yan, Jie Xu

Theranostics. 2018; 8(16): 4359–4371. Published online 2018 Jul 30. doi: 10.7150/thno.26900

PMCID:: PMC6134928

Abstract Article PDF–2.2M

Select item 607643918.

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin

Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342

PMCID:: PMC6076439

Abstract Article PDF–2.5M

Select item 586602419.

Pre-B cell leukemia transcription factor 3 induces inflammatory responses in human umbilical vein endothelial cells and murine sepsis via acting a competing endogenous RNA for high mobility group box 1 protein

Yunzhong Zhang, Jing Feng, Jizhen Cui, Guozheng Yang, Xianai Zhu

Mol Med Rep. 2018 Apr; 17(4): 5805–5813. Published online 2018 Feb 15. doi: 10.3892/mmr.2018.8609

PMCID:: PMC5866024

Abstract Article PDF–1.0M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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