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Select item 104805351.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 103259972.

Lottie D. Morison, Olivia van Reyk, Elana Forbes, Flavien Rouxel, Laurence Faivre, Fiona Bruinsma, Marie Vincent, Marie-Line Jacquemont, Natalie L. Dykzeul, David Geneviève, David J. Amor, Angela T. Morgan

Eur J Hum Genet. 2023 Jul; 31(7): 793–804. Published online 2023 Jan 4. doi: 10.1038/s41431-022-01275-8

Correction in:: Eur J Hum Genet. 2023 Dec 8

PMCID:: PMC10325997

Abstract Article PDF–2.8M

Select item 102879013.

CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1

Valentina Panzeri, Marco Pieraccioli, Eleonora Cesari, Pierre de la Grange, Claudio Sette

Nucleic Acids Res. 2023 Jun 23; 51(11): 5512–5526. Published online 2023 Apr 7. doi: 10.1093/nar/gkad258

PMCID:: PMC10287901

Abstract Article PDF–3.4M

Select item 101845534.

Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance

Megan L. Insco, Brian J. Abraham, Sara J. Dubbury, Ines H. Kaltheuner, Sofia Dust, Constance Wu, Kevin Y. Chen, David Liu, Stanislav Bellaousov, Anna M. Cox, Benjamin J.E. Martin, Tongwu Zhang, Calvin G. Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E. Esgdaille, Telmo Henriques, Kevin M. Brown, Stephen J. Chanock, Matthias Geyer, Karen Adelman, Phillip A. Sharp, Richard A. Young, Paul L. Boutz, Leonard I. Zon

Science. Author manuscript; available in PMC 2023 May 15.

Published in final edited form as: Science. 2023 Apr 21; 380(6642): eabn7625. Published online 2023 Apr 21. doi: 10.1126/science.abn7625

PMCID:: PMC10184553

Abstract Article PDF–2.1M

Select item 101645645.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 100729066.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99786357.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 97979888.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 97725589.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969810.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 948193311.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 943756312.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 934345513.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 926261414.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 911973615.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 874895816.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 847292417.

Wolfram-like syndrome with bicuspid aortic valve due to a homozygous missense variant in CDK13

Anushree Acharya, Syed Irfan Raza, Muhammad Zeeshan Anwar, Thashi Bharadwaj, Khurram Liaqat, Muhammad Akram Shahzad Khokhar, Jenna L. Everard, Abdul Nasir, University of Washington Center for Mendelian Genomics, Deborah A. Nickerson, Michael J. Bamshad, Muhammad Ansar, Isabelle Schrauwen, Wasim Ahmad, Suzanne M. Leal

J Hum Genet. 2021; 66(10): 1009–1018. Published online 2021 Apr 21. doi: 10.1038/s10038-021-00922-0

Correction in:: J Hum Genet. 2021; 66(10): 1019.

PMCID:: PMC8472924

Abstract Article PDF–1.2M

Select item 842498118.

An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks

Julia Ramírez-Moya, Christos Miliotis, Allison R. Baker, Richard I. Gregory, Frank J. Slack, Pilar Santisteban

Mol Cancer. 2021; 20: 115. Published online 2021 Sep 8. doi: 10.1186/s12943-021-01401-y

PMCID:: PMC8424981

Abstract Article PDF–3.1M

Select item 838564519.

HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity

Qingqing Chai, Sunan Li, Morgan K. Collins, Rongrong Li, Iqbal Ahmad, Silas F. Johnson, Dylan A. Frabutt, Zhichang Yang, Xiaojing Shen, Liangliang Sun, Jian Hu, Judd F. Hultquist, B. Matija Peterlin, Yong-Hui Zheng

Cell Rep. Author manuscript; available in PMC 2021 Aug 25.

Published in final edited form as: Cell Rep. 2021 Aug 10; 36(6): 109514. doi: 10.1016/j.celrep.2021.109514

PMCID:: PMC8385645

Abstract Article PDF–2.1M

Select item 836418120.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

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