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Items: 1 to 20 of 21

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
3.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
4.
Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b
John R. Bankston, Hannah A. DeBerg, Stefan Stoll, William N. Zagotta
J Biol Chem. 2017 Oct 27; 292(43): 17794–17803. Published online 2017 Sep 1. doi: 10.1074/jbc.M117.800722
PMCID:
PMC5663879
AbstractArticlePDF–1.5M
5.
Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels
Kyle A. Lyman, Ye Han, Robert J. Heuermann, Xiangying Cheng, Jonathan E. Kurz, Reagan E. Lyman, Paul P. Van Veldhoven, Dane M. Chetkovich
J Biol Chem. 2017 Oct 27; 292(43): 17718–17730. Published online 2017 Sep 8. doi: 10.1074/jbc.M117.802256
PMCID:
PMC5663874
AbstractArticlePDF–2.4M
6.
Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
Ye Han, Kyle A. Lyman, Matt Clutter, Gary E. Schiltz, Quratul-Ain Ismail, Xiangying Cheng, Chi-Hao Luan, Dane M. Chetkovich
J Vis Exp. 2016; (117): 54540. Published online 2016 Nov 11. doi: 10.3791/54540
PMCID:
PMC5145243
AbstractArticlePDF–311K
7.
Mechanistic Insights into PTS2-mediated Peroxisomal Protein Import: THE CO-RECEPTOR PEX5L DRASTICALLY INCREASES THE INTERACTION STRENGTH BETWEEN THE CARGO PROTEIN AND THE RECEPTOR PEX7
Markus Kunze, Naila Malkani, Sebastian Maurer-Stroh, Christoph Wiesinger, Johannes A. Schmid, Johannes Berger
J Biol Chem. 2015 Feb 20; 290(8): 4928–4940. Published online 2014 Dec 23. doi: 10.1074/jbc.M114.601575
PMCID:
PMC4335231
AbstractArticlePDF–2.2M
8.
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function
Andrea Saponaro, Sofia R. Pauleta, Francesca Cantini, Manolis Matzapetakis, Christian Hammann, Chiara Donadoni, Lei Hu, Gerhard Thiel, Lucia Banci, Bina Santoro, Anna Moroni
Proc Natl Acad Sci U S A. 2014 Oct 7; 111(40): 14577–14582. Published online 2014 Sep 2. doi: 10.1073/pnas.1410389111
PMCID:
PMC4210022
AbstractArticlePDF–1.0M
9.
TRIP8b-Independent Trafficking and Plasticity of Adult Cortical Presynaptic HCN1 Channels
Zhuo Huang, Rafael Lujan, Jose Martinez-Hernandez, Alan S. Lewis, Dane M. Chetkovich, Mala M. Shah
J Neurosci. 2012 Oct 17; 32(42): 14835–14848. doi: 10.1523/JNEUROSCI.1544-12.2012
PMCID:
PMC4104472
AbstractArticlePDF–4.1M
10.
An atlas of genetic influences on human blood metabolites
So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo
Nat Genet. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982
PMCID:
PMC4064254
AbstractArticlePDF–2.4M
11.
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins
Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins
Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110
PMCID:
PMC3581954
AbstractArticlePDF–2.3M
12.
Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels
John R. Bankston, Stacey S. Camp, Frank DiMaio, Alan S. Lewis, Dane M. Chetkovich, William N. Zagotta
Proc Natl Acad Sci U S A. 2012 May 15; 109(20): 7899–7904. Published online 2012 May 1. doi: 10.1073/pnas.1201997109
PMCID:
PMC3356637
AbstractArticlePDF–1.1M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Trafficking and Gating of Hyperpolarization-activated Cyclic Nucleotide-gated Channels Are Regulated by Interaction with Tetratricopeptide Repeat-containing Rab8b-interacting Protein (TRIP8b) and Cyclic AMP at Distinct Sites
Ye Han, Yoav Noam, Alan S. Lewis, Johnie J. Gallagher, Wytse J. Wadman, Tallie Z. Baram, Dane M. Chetkovich
J Biol Chem. 2011 Jun 10; 286(23): 20823–20834. Published online 2011 Apr 19. doi: 10.1074/jbc.M111.236125
PMCID:
PMC3121500
AbstractArticlePDF–2.1M
15.
Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia
Xueling Sim, Rick Twee-Hee Ong, Chen Suo, Wan-Ting Tay, Jianjun Liu, Daniel Peng-Keat Ng, Michael Boehnke, Kee-Seng Chia, Tien-Yin Wong, Mark Seielstad, Yik-Ying Teo, E-Shyong Tai
PLoS Genet. 2011 Apr; 7(4): e1001363. Published online 2011 Apr 7. doi: 10.1371/journal.pgen.1001363
PMCID:
PMC3072366
AbstractArticlePDF–1.0M
16.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
17.
A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication
Man Lung Yeung, Laurent Houzet, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang
J Biol Chem. 2009 Jul 17; 284(29): 19463–19473. Published online 2009 May 20. doi: 10.1074/jbc.M109.010033
PMCID:
PMC2740572
AbstractArticlePDF–2.5M
18.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
19.
Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.
L Amery, H Sano, G P Mannaerts, J Snider, J Van Looy, M Fransen, P P Van Veldhoven
Biochem J. 2001 Aug 1; 357(Pt 3): 635–646. doi: 10.1042/0264-6021:3570635
PMCID:
PMC1221994
SummaryPDF–597K
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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