PMC Links for GEO Profiles (Select 22835541) - PMC

Select item 104998211.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 104782282.

Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

Deze Zhao, Yeping Dong, Minghao Duan, Dan He, Qun Xie, Wei Peng, Weifang Cui, Junjie Jiang, Yuanda Cheng, Heng Zhang, Faqing Tang, Chunfang Zhang, Yang Gao, Chaojun Duan

J Exp Clin Cancer Res. 2023; 42: 229. Published online 2023 Sep 4. doi: 10.1186/s13046-023-02791-1

PMCID:: PMC10478228

Abstract Article PDF–9.1M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 61007245.

Proteome‐wide analysis of phospho‐regulated PDZ domain interactions

Gustav N Sundell, Roland Arnold, Muhammad Ali, Piangfan Naksukpaiboon, Julien Orts, Peter Güntert, Celestine N Chi, Ylva Ivarsson

Mol Syst Biol. 2018 Aug; 14(8): e8129. Published online 2018 Aug 20. doi: 10.15252/msb.20178129

PMCID:: PMC6100724

Abstract Article PDF–2.4M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 42292117.

Genome-Wide and Gene-Based Association Studies of Anxiety Disorders in European and African American Samples

Takeshi Otowa, Brion S. Maher, Steven H. Aggen, Joseph L. McClay, Edwin J. van den Oord, John M. Hettema

PLoS One. 2014; 9(11): e112559. Published online 2014 Nov 12. doi: 10.1371/journal.pone.0112559

PMCID:: PMC4229211

Abstract Article PDF–211K

Select item 41410238.

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca²⁺ concentration via activation of Src kinase and nitric oxide signaling pathways

Kelly A Krogh, Nicole Wydeven, Kevin Wickman, Stanley A. Thayer

J Neurochem. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: J Neurochem. 2014 Sep; 130(5): 642–656. Published online 2014 Apr 19. doi: 10.1111/jnc.12724

PMCID:: PMC4141023

Abstract Article PDF–1.7M

Select item 40199819.

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger

Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750

PMCID:: PMC4019981

Abstract Article PDF–915K

Select item 398572110.

Interfacial Residues Promote an Optimal Alignment of the Catalytic Center in Human Soluble Guanylate Cyclase: Heterodimerization Is Required but Not Sufficient for Activity

Franziska Seeger, Royston Quintyn, Akiko Tanimoto, Gareth J. Williams, John A. Tainer, Vicki H. Wysocki, Elsa D. Garcin

Biochemistry. 2014 Apr 8; 53(13): 2153–2165. Published online 2014 Mar 14. doi: 10.1021/bi500129k

PMCID:: PMC3985721

Abstract Article PDF–8.1M

Select item 393293311.

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Ylva Ivarsson, Roland Arnold, Megan McLaughlin, Satra Nim, Rakesh Joshi, Debashish Ray, Bernard Liu, Joan Teyra, Tony Pawson, Jason Moffat, Shawn Shun-Cheng Li, Sachdev S. Sidhu, Philip M. Kim

Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7): 2542–2547. Published online 2014 Feb 3. doi: 10.1073/pnas.1312296111

PMCID:: PMC3932933

Abstract Article PDF–1.0M

Select item 352258712.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 334973413.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695