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Items: 1 to 20 of 60

1.
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers
Derek P. Wong, Nand K. Roy, Keman Zhang, Anusha Anukanth, Abhishek Asthana, Nicole J. Shirkey-Son, Samantha Dunmire, Bryan J. Jones, Walker S. Lahr, Beau R. Webber, Branden S. Moriarity, Paolo Caimi, Reshmi Parameswaran
Nat Commun. 2022; 13: 217. Published online 2022 Jan 11. doi: 10.1038/s41467-021-27853-w
PMCID:
PMC8752722
AbstractArticlePDF–3.6M
2.
TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells
Mayara Garcia de Mattos Barbosa, Adam R. Lefferts, Daniel Huynh, Hui Liu, Yu Zhang, Beverly Fu, Jenna Barnes, Milagros Samaniego, Richard J. Bram, Raif S. Geha, Ariella Shikanov, Eline T. Luning Prak, Evan A. Farkash, Jeffrey L. Platt, Marilia Cascalho
JCI Insight. 2021 Sep 8; 6(17): e150483. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150483
PMCID:
PMC8492324
AbstractArticlePDF–1.6M
3.
TACI Mutations in Primary Antibody Deficiencies: A Nationwide Study in Greece
Ioannis Kakkas, Gerasimina Tsinti, Fani Kalala, Evangelia Farmaki, Alexandra Kourakli, Androniki Kapousouzi, Maria Dimou, Vassiliki Kalaitzidou, Eirini Sevdali, Athanasia-Marina Peristeri, Georgia Tsiouma, Peristera Patiou, Eleni Papadimitriou, Theodoros P. Vassilakopoulos, Panayiotis Panayiotidis, Anna Kioumi, Argiris Symeonidis, Matthaios Speletas
Medicina (Kaunas) 2021 Aug; 57(8): 827. Published online 2021 Aug 16. doi: 10.3390/medicina57080827
PMCID:
PMC8401742
AbstractArticlePDF–295K
4.
TNFRSF13B c.226G>A (p.Gly76Ser) as a Novel Causative Mutation for Pulmonary Arterial Hypertension
Yoshiki Shinya, Takahiro Hiraide, Mizuki Momoi, Shinichi Goto, Hisato Suzuki, Yoshinori Katsumata, Yutaka Kurebayashi, Jin Endo, Motoaki Sano, Keiichi Fukuda, Kenjiro Kosaki, Masaharu Kataoka
J Am Heart Assoc. 2021 Mar 2; 10(5): e019245. Published online 2021 Feb 15. doi: 10.1161/JAHA.120.019245
PMCID:
PMC8174299
AbstractArticlePDF–473K
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications
Yu-Tzu Tai, Liang Lin, Lijie Xing, Shih-Feng Cho, Tengteng Yu, Chirag Acharya, Kenneth Wen, Phillip A Hsieh, John Dulos, Andrea van Elsas, Nikhil Munshi, Paul Richardson, Kenneth C Anderson
Leukemia. Author manuscript; available in PMC 2019 Feb 22.
Published in final edited form as: Leukemia. 2019 Feb; 33(2): 426–438. Published online 2018 Aug 22. doi: 10.1038/s41375-018-0242-6
PMCID:
PMC6367000
AbstractArticlePDF–688K
8.
TACI Isoforms Regulate Ligand Binding and Receptor Function
Yolanda Garcia-Carmona, Adrian T. Ting, Lin Radigan, Sai Krishna Athuluri Divakar, Jose Chavez, Eric Meffre, Andrea Cerutti, Charlotte Cunningham-Rundles
Front Immunol. 2018; 9: 2125. Published online 2018 Oct 2. doi: 10.3389/fimmu.2018.02125
Correction in:
Front Immunol. 2019; 10: 2772.
PMCID:
PMC6176016
AbstractArticlePDF–1.3M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice
Haifa H. Jabara, John J. Lee, Erin Janssen, Sumana Ullas, Kyriaki Liadaki, Lilit Garibyan, Halli Benson, Tatyana Sannikova, Richard Bram, Lennart Hammarstrom, Anthony C. Cruz, Richard Siegel, John Manis, Richard Malley, Raif S. Geha
J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Apr; 139(4): 1293–1301.e4. Published online 2016 Sep 5. doi: 10.1016/j.jaci.2016.07.028
PMCID:
PMC5337448
AbstractArticlePDF–1.1M
11.
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk
Daniel Chubb, Niels Weinhold, Peter Broderick, Bowang Chen, David C Johnson, Asta Försti, Jayaram Vijayakrishnan, Gabriele Migliorini, Sara E Dobbins, Amy Holroyd, Dirk Hose, Brian A Walker, Faith E Davies, Walter A Gregory, Graham H Jackson, Julie A Irving, Guy Pratt, Chris Fegan, James AL Fenton, Kai Neben, Per Hoffmann, Markus M Nöthen, Thomas W Mühleisen, Lewin Eisele, Fiona M Ross, Christian Straka, Hermann Einsele, Christian Langer, Elisabeth Dörner, James M Allan, Anna Jauch, Gareth J Morgan, Kari Hemminki, Richard S Houlston, Hartmut Goldschmidt
Nat Genet. Author manuscript; available in PMC 2016 Oct 6.
Published in final edited form as: Nat Genet. 2013 Oct; 45(10): 1221–1225. Published online 2013 Aug 18. doi: 10.1038/ng.2733
PMCID:
PMC5053356
AbstractArticlePDF–750K
12.
Clinical Associations of Biallelic and Monoallelic TNFRSF13B Variants in Italian Primary Antibody Deficiency Syndromes
Federica Pulvirenti, Roberta Zuntini, Cinzia Milito, Fernando Specchia, Giuseppe Spadaro, Maria Giovanna Danieli, Andrea Pession, Isabella Quinti, Simona Ferrari
J Immunol Res. 2016; 2016: 8390356. Published online 2016 Mar 30. doi: 10.1155/2016/8390356
PMCID:
PMC4829724
AbstractArticlePDF–738K
13.
TNFRSF13B hemizygosity reveals TACI haploinsufficiency at later stages of B-cell development
Neil Romberg, Manmeet Virdee, Nicolas Chamberlain, Tyler Oe, Jean-Nicolas Schickel, Tiffany Perkins, Tineke Cantaert, Rima Rachid, Sally Rosengren, Regina Palazzo, Raif Geha, Charlotte Cunningham-Rundles, Eric Meffre
J Allergy Clin Immunol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Nov; 136(5): 1315–1325. Published online 2015 Jun 19. doi: 10.1016/j.jaci.2015.05.012
PMCID:
PMC4641026
AbstractArticlePDF–4.0M
14.
Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders
Pauline A. van Schouwenburg, Emma E. Davenport, Anne-Kathrin Kienzler, Ishita Marwah, Benjamin Wright, Mary Lucas, Tomas Malinauskas, Hilary C. Martin, WGS500 Consortium, Helen E. Lockstone, Jean-Baptiste Cazier, Helen M. Chapel, Julian C. Knight, Smita Y. Patel
Clin Immunol. Author manuscript; available in PMC 2015 Oct 12.
Published in final edited form as: Clin Immunol. 2015 Oct; 160(2): 301–314. Published online 2015 Jun 26. doi: 10.1016/j.clim.2015.05.020
PMCID:
PMC4601528
AbstractArticlePDF–2.2M
15.
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal
Cell. Author manuscript; available in PMC 2016 Apr 23.
Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013
PMCID:
PMC4441215
AbstractArticlePDF–1.2M
16.
TACI Expression and Signaling in Chronic Lymphocytic Leukemia
Antigoni Mamara, Anastasios E. Germenis, Maria Kompoti, Maria Palassopoulou, Eudokia Mandala, Anastasia Banti, Nikolaos Giannakoulas, Matthaios Speletas
J Immunol Res. 2015; 2015: 478753. Published online 2015 Apr 9. doi: 10.1155/2015/478753
PMCID:
PMC4408744
AbstractArticlePDF–1.2M
17.
Effect of TACI Signaling on Humoral Immunity and Autoimmune Diseases
Yi Zhang, Jun Li, Ya-Min Zhang, Xiao-Ming Zhang, Juan Tao
J Immunol Res. 2015; 2015: 247426. Published online 2015 Mar 17. doi: 10.1155/2015/247426
PMCID:
PMC4381970
AbstractArticlePDF–1.0M
18.
Differential induction of plasma cells by isoforms of human TACI
Yolanda Garcia-Carmona, Montserrat Cols, Adrian T. Ting, Lin Radigan, Frank J. Yuk, Li Zhang, Andrea Cerutti, Charlotte Cunningham-Rundles
Blood. 2015 Mar 12; 125(11): 1749–1758. Prepublished online 2015 Jan 28. doi: 10.1182/blood-2014-05-575845
Correction in:
Blood. 2019 Sep 5; 134(10): 843.
PMCID:
PMC4357582
AbstractArticle
19.
B-cell activating factor in the pathophysiology of multiple myeloma: a target for therapy?
P J Hengeveld, M J Kersten
Blood Cancer J. 2015 Feb; 5(2): e282. Published online 2015 Feb 27. doi: 10.1038/bcj.2015.3
PMCID:
PMC4349256
AbstractArticlePDF–1.7M
20.
The immunoregulator soluble TACI is released by ADAM10 and reflects B-cell activation in autoimmunity
Franziska S. Hoffmann, Peer-Hendrik Kuhn, Sarah A. Laurent, Stefanie M. Hauck, Kerstin Berer, Simone A. Wendlinger, Markus Krumbholz, Mohsen Khademi, Tomas Olsson, Martin Dreyling, Hans-Walter Pfister, Tobias Alexander, Falk Hiepe, Tania Kümpfel, Howard C. Crawford, Hartmut Wekerle, Reinhard Hohlfeld, Stefan F. Lichtenthaler, Edgar Meinl
J Immunol. Author manuscript; available in PMC 2016 Jan 15.
Published in final edited form as: J Immunol. 2015 Jan 15; 194(2): 542–552. Published online 2014 Dec 10. doi: 10.4049/jimmunol.1402070
PMCID:
PMC4282951
AbstractArticlePDF–2.3M

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