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Select item 106518731.

Hereditary platelet disorders associated with germ line variants in RUNX1, ETV6, and ANKRD26

Claire C. Homan, Hamish S. Scott, Anna L. Brown

Blood. 2023 Mar 30; 141(13): 1533–1543. Published online 2023 Jan 13. doi: 10.1182/blood.2022017735

PMCID:: PMC10651873

Abstract Article

Select item 96363092.

Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations

Michael W. Drazer, Claire C. Homan, Kai Yu, Marcela Cavalcante de Andrade Silva, Kelsey E. McNeely, Matthew J. Pozsgai, Maria G. Acevedo-Mendez, Jeremy P. Segal, Peng Wang, Jinghua Feng, Sarah L. King-Smith, Erika Kim, Sophia Korotev, David M. Lawrence, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Raman Sood, Elvira D.R.P. Velloso, Anna L. Brown, Paul P. Liu, Lucy A. Godley, NISC Comparative Sequencing Program

Blood Adv. 2022 Aug 9; 6(15): 4357–4359. Published online 2022 May 12. doi: 10.1182/bloodadvances.2022007211

PMCID:: PMC9636309

Article PDF–643K

Select item 95699553.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 95552744.

Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases

Hrushikesh Vyas, Ahmad Alcheikh, Gillian Lowe, William S Stevenson, Neil V Morgan, David J Rabbolini

Platelets. 2022; 33(8): 1107–1112. Published online 2022 May 19. doi: 10.1080/09537104.2022.2071853

PMCID:: PMC9555274

Abstract Article PDF–918K

Select item 95212475.

Platelet functional abnormalities and clinical presentation in pediatric patients with germline RUNX1, ANKRD26, and ETV6 mutations

Galina S. Ovsyannikova, Daria V. Fedorova, Ivan P. Tesakov, Alexey A. Martyanov, Anastasia A. Ignatova, Evgeniya A. Ponomarenko, Pavel A. Zharkov, Anna V. Pavlova, Elena V. Raykina, Michael A. Maschan, Mikhail A. Panteleev, Galina A. Novichkova, Anastasia N. Sveshnikova, Nataliya S. Smetanina

Haematologica. 2022 Oct 1; 107(10): 2511–2516. Published online 2022 Jul 7. doi: 10.3324/haematol.2022.281340

PMCID:: PMC9521247

Article PDF–5.7M

Select item 94339386.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 91714117.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 85664739.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 855290710.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 855075911.

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy

Tomasz Radaszkiewicz, Michaela Nosková, Kristína Gömöryová, Olga Vondálová Blanářová, Katarzyna Anna Radaszkiewicz, Markéta Picková, Ráchel Víchová, Tomáš Gybeľ, Karol Kaiser, Lucia Demková, Lucia Kučerová, Tomáš Bárta, David Potěšil, Zbyněk Zdráhal, Karel Souček, Vítězslav Bryja

eLife. 2021; 10: e65759. Published online 2021 Oct 27. doi: 10.7554/eLife.65759

PMCID:: PMC8550759

Abstract Article PDF–7.4M

Select item 825771212.

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

David Schlütermann, Niklas Berleth, Jana Deitersen, Nora Wallot-Hieke, Olena Friesen, Wenxian Wu, Fabian Stuhldreier, Yadong Sun, Lena Berning, Annabelle Friedrich, María José Mendiburo, Christoph Peter, Constanze Wiek, Helmut Hanenberg, Anja Stefanski, Kai Stühler, Björn Stork

Sci Rep. 2021; 11: 13863. Published online 2021 Jul 5. doi: 10.1038/s41598-021-92408-4

PMCID:: PMC8257712

Abstract Article PDF–3.2M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 805675214.

Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript

Lara Wahlster, Jeffrey M. Verboon, Leif S. Ludwig, Susan C. Black, Wendy Luo, Kopal Garg, Richard A. Voit, Ryan L. Collins, Kiran Garimella, Maura Costello, Katherine R. Chao, Julia K. Goodrich, Stephanie P. DiTroia, Anne O’Donnell-Luria, Michael E. Talkowski, Alan D. Michelson, Alan B. Cantor, Vijay G. Sankaran

J Exp Med. 2021 Jun 7; 218(6): e20210444. Published online 2021 Apr 15. doi: 10.1084/jem.20210444

PMCID:: PMC8056752

Abstract Article PDF–3.1M

Select item 803721115.

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective

Veronique Jonckheere, Petra Van Damme

Int J Mol Sci. 2021 Apr; 22(7): 3690. Published online 2021 Apr 1. doi: 10.3390/ijms22073690

PMCID:: PMC8037211

Abstract Article PDF–6.5M

Select item 689427716.

Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

Antonella Desiderio, Michele Longo, Luca Parrillo, Michele Campitelli, Giuseppe Cacace, Sonia de Simone, Rosa Spinelli, Federica Zatterale, Serena Cabaro, Pasquale Dolce, Pietro Formisano, Marco Milone, Claudia Miele, Francesco Beguinot, Gregory A. Raciti

Clin Epigenetics. 2019; 11: 181. Published online 2019 Dec 4. doi: 10.1186/s13148-019-0768-0

PMCID:: PMC6894277

Abstract Article PDF–1.1M

Select item 677813717.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 671373618.

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins

Sascha E. Dho, Nancy Silva-Gagliardi, Fabio Morgese, Etienne Coyaud, Emily Lamoureux, Donna M. Berry, Brian Raught, C. Jane McGlade

Sci Rep. 2019; 9: 12471. Published online 2019 Aug 28. doi: 10.1038/s41598-019-48902-x

PMCID:: PMC6713736

Abstract Article PDF–5.6M

Select item 639721019.

High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy

Mathew Bowler, Dong Kong, Shufeng Sun, Rashmi Nanjundappa, Lauren Evans, Veronica Farmer, Andrew Holland, Moe R. Mahjoub, Haixin Sui, Jadranka Loncarek

Nat Commun. 2019; 10: 993. Published online 2019 Mar 1. doi: 10.1038/s41467-018-08216-4

PMCID:: PMC6397210

Abstract Article PDF–7.7M

Select item 638658820.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

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