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Select item 109238761.

Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis

Bin Zhang, Jie Li, Yijun Wang, Xixi Liu, Xiao Yang, Zhiyun Liao, Suke Deng, Yue Deng, Zhiyuan Zhou, Yu Tian, Wenwen Wei, Jingshu Meng, Yan Hu, Chao Wan, Zhanjie Zhang, Fang Huang, Lu Wen, Bian Wu, Yajie Sun, Yan Li, Kunyu Yang

Cell Death Differ. 2024 Mar; 31(3): 309–321. Published online 2024 Jan 29. doi: 10.1038/s41418-024-01257-x

PMCID:: PMC10923876

Abstract Article PDF–8.3M

Select item 105471982.

Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify KDM5B as a risk gene

Thomas V. Fernandez, Zsanett P. Williams, Tina Kline, Shreenath Rajendran, Farhan Augustine, Nicole Wright, Catherine A. W. Sullivan, Emily Olfson, Sarah B. Abdallah, Wenzhong Liu, Ellen J. Hoffman, Abha R. Gupta, Harvey S. Singer

PLoS One. 2023; 18(10): e0291978. Published online 2023 Oct 3. doi: 10.1371/journal.pone.0291978

PMCID:: PMC10547198

Abstract Article PDF–1.2M

Select item 102818643.

A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression

Elena Di Nisio, Valerio Licursi, Cecilia Mannironi, Valentina Buglioni, Alessandro Paiardini, Giulia Robusti, Roberta Noberini, Tiziana Bonaldi, Rodolfo Negri

Cancer Gene Ther. 2023; 30(6): 822–832. Published online 2023 Jan 26. doi: 10.1038/s41417-022-00584-w

PMCID:: PMC10281864

Abstract Article PDF–3.0M

Select item 102405544.

PLU1 Promotes the Proliferation and Migration of Glioma Cells and Regulates Metabolism

Wentao Dong, Lude Wang, Yi Pan, Qi Tu, Ting He, Tian Zhou, Jianlie Yuan, Minfeng Tong

Technol Cancer Res Treat. 2023; 22: 15330338231175768. Published online 2023 May 30. doi: 10.1177/15330338231175768

PMCID:: PMC10240554

Abstract Article PDF–4.6M

Select item 97948215.

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis

Jung Yoo, Go Woon Kim, Yu Hyun Jeon, Ji Yoon Kim, Sang Wu Lee, So Hee Kwon

Exp Mol Med. 2022 Dec; 54(12): 2107–2117. Published online 2022 Dec 12. doi: 10.1038/s12276-022-00902-0

PMCID:: PMC9794821

Abstract Article PDF–2.1M

Select item 94266286.

H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity

Runsheng He, Besa Xhabija, Lijin K. Gopi, Jiji T. Kurup, Zhishan Xu, Zhe Liu, Benjamin L. Kidder

Oncogene. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Oncogene. 2022 May; 41(21): 2958–2972. Published online 2022 Apr 19. doi: 10.1038/s41388-022-02311-z

PMCID:: PMC9426628

Abstract Article PDF–4.1M

Select item 93485767.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91246158.

Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss

Xiaobo Wang, Min Gu, Yongjian Ju, Juying Zhou

J Radiat Res. 2022 May; 63(3): 331–341. Published online 2022 Mar 25. doi: 10.1093/jrr/rrac004

PMCID:: PMC9124615

Abstract Article PDF–2.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 901471110.

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach

Cell Rep. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030

PMCID:: PMC9014711

Abstract Article PDF–2.2M

Select item 901280111.

KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis

Binbin Chen, Huimou Chen, Suying Lu, Xiaoqin Zhu, Yi Que, Yu Zhang, Junting Huang, Li Zhang, Yu Zhang, Feifei Sun, Juan Wang, Jia Zhu, Zijun Zhen, Yizhuo Zhang

Cell Death Dis. 2022 Apr; 13(4): 354. Published online 2022 Apr 15. doi: 10.1038/s41419-022-04800-1

PMCID:: PMC9012801

Abstract Article PDF–6.9M

Select item 884414512.

Circ_0087960 stabilizes KDM5B by reducing SKP2 mediated ubiquitination degradation and promotes osteogenic differentiation in periodontal ligament stem cells

Yinchen Liu, Yanbin Zhou

Regen Ther. 2022 Mar; 19: 122–130. Published online 2022 Feb 10. doi: 10.1016/j.reth.2022.01.003

PMCID:: PMC8844145

Abstract Article PDF–2.5M

Select item 871962213.

Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B

Bingluo Zhou, Yiran Zhu, Wenxia Xu, Qiyin Zhou, Linghui Tan, Liyuan Zhu, Hui Chen, Lifeng Feng, Tianlun Hou, Xian Wang, Dingwei Chen, Hongchuan Jin

Front Cell Dev Biol. 2021; 9: 741736. Published online 2021 Dec 17. doi: 10.3389/fcell.2021.741736

PMCID:: PMC8719622

Abstract Article PDF–3.7M

Select item 855546414.

KDM5B Promotes Immune Evasion by Recruiting SETDB1 to Silence Retroelements

Shang-Min Zhang, Wesley L. Cai, Xiaoni Liu, Durga Thakral, Jiesi Luo, Lok Hei Chan, Meaghan K. McGeary, Eric Song, Kim RM Blenman, Goran Micevic, Shlomit Jessel, Yangyi Zhang, Mingzhu Yin, Carmen J. Booth, Lucia B. Jilaveanu, William Damsky, Mario Sznol, Harriet M. Kluger, Akiko Iwasaki, Marcus W. Bosenberg, Qin Yan

Nature. Author manuscript; available in PMC 2022 Apr 20.

Published in final edited form as: Nature. 2021 Oct; 598(7882): 682–687. Published online 2021 Oct 20. doi: 10.1038/s41586-021-03994-2

PMCID:: PMC8555464

Abstract Article PDF–5.8M

Select item 846752215.

Agenesis of the Corpus Callosum with Facial Dysmorphism and Intellectual Disability in Sibs Associated with Compound Heterozygous KDM5B Variants

Sébastien Lebon, Mathieu Quinodoz, Virginie G. Peter, Carole Gengler, Gaëlle Blanchard, Viviane Cina, Belinda Campos-Xavier, Carlo Rivolta, Andrea Superti-Furga

Genes (Basel) 2021 Sep; 12(9): 1397. Published online 2021 Sep 10. doi: 10.3390/genes12091397

PMCID:: PMC8467522

Abstract Article PDF–592K

Select item 818190016.

KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance

Solenne Gaillard, Virginie Charasson, Cyril Ribeyre, Kader Salifou, Marie-Jeanne Pillaire, Jean-Sebastien Hoffmann, Angelos Constantinou, Didier Trouche, Marie Vandromme

Biol Open. 2021 May 15; 10(5): bio057729. Published online 2021 May 26. doi: 10.1242/bio.057729

PMCID:: PMC8181900

Abstract Article PDF–5.6M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803484218.

KDM5B is essential for the hyper-activation of PI3K/AKT signaling in prostate tumorigenesis

Guoliang Li, Thanigaivelan Kanagasabai, Wenfu Lu, Mike R. Zou, Shang-Min Zhang, Sherly I. Celada, Michael G. Izban, Qi Liu, Tao Lu, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Qin Yan, Zhenbang Chen

Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Cancer Res. 2020 Nov 1; 80(21): 4633–4643. Published online 2020 Aug 31. doi: 10.1158/0008-5472.CAN-20-0505