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Select item 111587071.

Chicken ovalbumin upstream promoter transcription factor II in human breast carcinoma: Possible regulator of lymphangiogenesis via vascular endothelial growth factor‐C expression

Shuji Nagasaki, Takashi Suzuki, Yasuhiro Miki, Jun‐ichi Akahira, Hirotaka Shibata, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano

Cancer Sci. 2009 Apr; 100(4): 639–645. Published online 2009 Jan 13. doi: 10.1111/j.1349-7006.2008.01078.x

PMCID:: PMC11158707

Abstract Article PDF–547K

Select item 102024902.

Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss

Edward J. Dougherty, Li-Yuan Chen, Keytam S. Awad, Gabriela A. Ferreyra, Cumhur Y. Demirkale, Ali Keshavarz, Salina Gairhe, Kathryn A. Johnston, Madelyn E. Hicks, Alexis B. Sandler, Colleen S. Curran, Janell M. Krack, Yi Ding, Anthony F. Suffredini, Michael A. Solomon, Jason M. Elinoff, Robert L. Danner

Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1; 324(6): L783–L798. Published online 2023 Apr 11. doi: 10.1152/ajplung.00171.2022

PMCID:: PMC10202490

Abstract Article

Select item 100731093.

An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma

Veronica Davalos, Claudia D. Lovell, Richard Von Itter, Igor Dolgalev, Praveen Agrawal, Gillian Baptiste, David J. Kahler, Elena Sokolova, Sebastian Moran, Laia Piqué, Eleazar Vega-Saenz de Miera, Barbara Fontanals-Cirera, Alcida Karz, Aristotelis Tsirigos, Chi Yun, Farbod Darvishian, Heather C. Etchevers, Iman Osman, Manel Esteller, Markus Schober, Eva Hernando

Nat Commun. 2023; 14: 1867. Published online 2023 Apr 4. doi: 10.1038/s41467-023-36967-2

PMCID:: PMC10073109

Abstract Article PDF–3.7M

Select item 93434554.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 92902415.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92626147.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 91052359.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 889438010.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2

PMCID:: PMC8894380

Abstract Article PDF–5.6M

Select item 855290711.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 819840412.

The miR-106b/NR2F2-AS1/PLEKHO2 Axis Regulates Migration and Invasion of Colorectal Cancer through the MAPK Pathway

Shuzhen Liu, Guoyan An, Qing Cao, Tong Li, Xinyu Jia, Lei Lei

Int J Mol Sci. 2021 Jun; 22(11): 5877. Published online 2021 May 30. doi: 10.3390/ijms22115877

PMCID:: PMC8198404

Abstract Article PDF–7.1M

Select item 816846213.

Decidual NR2F2-Expressing CD4⁺ T Cells Promote TH2 Transcriptional Program During Early Pregnancy

Yikong Lin, Di Zhang, Yangyang Li, Yunyun Li, Bin Li, Meirong Du

Front Immunol. 2021; 12: 670777. Published online 2021 May 18. doi: 10.3389/fimmu.2021.670777

PMCID:: PMC8168462

Abstract Article PDF–2.4M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 801666715.

YAP1 overexpression contributes to the development of enzalutamide resistance by induction of cancer stemness and lipid metabolism in prostate cancer

Hsiu-Chi Lee, Chien-Hui Ou, Yun-Chen Huang, Pei-Chi Hou, Chad J. Creighton, Yi-Syuan Lin, Che-Yuan Hu, Shih-Chieh Lin

Oncogene. 2021; 40(13): 2407–2421. Published online 2021 Mar 4. doi: 10.1038/s41388-021-01718-4

Correction in:: Oncogene. 2021; 40(23): 4060.

PMCID:: PMC8016667

Abstract Article PDF–5.7M

Select item 784975616.

The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene

Cristina Fugazza, Gloria Barbarani, Sudharshan Elangovan, Maria Giuseppina Marini, Serena Giolitto, Isaura Font-Monclus, Maria Franca Marongiu, Laura Manunza, John Strouboulis, Claudio Cantu, Fabio Gasparri, Silvia M.L. Barabino, Yukio Nakamura, Sergio Ottolenghi, Paolo Moi, Antonella Ellena Ronchi

Haematologica. 2021 Feb 1; 106(2): 474–482. Published online 2020 Feb 27. doi: 10.3324/haematol.2019.241224

PMCID:: PMC7849756

Abstract Article PDF–1.8M

Select item 772476017.

Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Jonathan P. Davies, Katherine M. Almasy, Eli F. McDonald, Lars Plate

ACS Infect Dis. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: ACS Infect Dis. 2020 Dec 11; 6(12): 3174–3189. Published online 2020 Dec 2. doi: 10.1021/acsinfecdis.0c00500

PMCID:: PMC7724760

Abstract Article PDF–2.1M

Select item 769151418.

The absence of (TCAGGG)_n repeats in some telomeres, combined with variable responses to NR2F2 depletion, suggest that this nuclear receptor plays an indirect role in the alternative lengthening of telomeres

Ahmed S. N. Alhendi, Nicola J. Royle

Sci Rep. 2020; 10: 20597. Published online 2020 Nov 26. doi: 10.1038/s41598-020-77606-w

PMCID:: PMC7691514

Abstract Article PDF–7.2M

Select item 768833619.

Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2

Gan Zhao, Aaron I. Weiner, Katherine M. Neupauer, Maria Fernanda de Mello Costa, Gargi Palashikar, Stephanie Adams-Tzivelekidis, Nilam S. Mangalmurti, Andrew E. Vaughan

Sci Adv. 2020 Nov; 6(48): eabc4493. Published online 2020 Nov 25. doi: 10.1126/sciadv.abc4493

PMCID:: PMC7688336

Abstract Article PDF–11M

Select item 734032020.

Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction

Chung-Yang Kao, Mafei Xu, Leiming Wang, Shih-Chieh Lin, Hui-Ju Lee, Lita Duraine, Hugo J. Bellen, David S. Goldstein, Sophia Y. Tsai, Ming-Jer Tsai

PLoS Genet. 2020 Jun; 16(6): e1008868. Published online 2020 Jun 24. doi: 10.1371/journal.pgen.1008868

PMCID:: PMC7340320

Abstract Article PDF–3.4M

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