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Select item 101664511.

EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation

Adekunle T. Bademosi, Marianna Decet, Sabine Kuenen, Carles Calatayud, Jef Swerts, Sandra F. Gallego, Nils Schoovaerts, Spyridoula Karamanou, Nikolaos Louros, Ella Martin, Jean-Baptiste Sibarita, Katlijn Vints, Natalia V. Gounko, Frédéric A. Meunier, Anastassios Economou, Wim Versées, Frederic Rousseau, Joost Schymkowitz, Sandra-F. Soukup, Patrik Verstreken

Neuron. 2023 May 3; 111(9): 1402–1422.e13. doi: 10.1016/j.neuron.2023.02.001

PMCID:: PMC10166451

Abstract Article

Select item 99868172.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 91714113.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 83641815.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 68610067.

A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency

Xiao Min Zhang, Urielle François, Kätlin Silm, Maria Florencia Angelo, Maria Victoria Fernandez-Busch, Mona Maged, Christelle Martin, Véronique Bernard, Fabrice P Cordelières, Melissa Deshors, Stéphanie Pons, Uwe Maskos, Alexis Pierre Bemelmans, Sonja M Wojcik, Salah El Mestikawy, Yann Humeau, Etienne Herzog

eLife. 2019; 8: e50401. Published online 2019 Oct 30. doi: 10.7554/eLife.50401

PMCID:: PMC6861006

Abstract Article PDF–3.4M

Select item 67623098.

Association of Trk Neurotrophin Receptors with Components of the Cytoplasmic Dynein Motor

Hiroko Yano, Francis S. Lee, Haeyoung Kong, Jen-Zen Chuang, Juan Carlos Arevalo, Pilar Perez, Ching-Hwa Sung, Moses V. Chao

J Neurosci. 2001 Feb 1; 21(3): RC125. doi: 10.1523/JNEUROSCI.21-03-j0003.2001

PMCID:: PMC6762309

Abstract PDF–1.1M

Select item 66909929.

Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles

Anbarasu Kannan, Julie V. Philley, Kate L. Hertweck, Harrison Ndetan, Karan P. Singh, Subramanium Sivakumar, Robert B. Wells, Ratna K. Vadlamudi, Santanu Dasgupta

Sci Rep. 2019; 9: 11632. Published online 2019 Aug 12. doi: 10.1038/s41598-019-48064-w

Correction in:: Sci Rep. 2020; 10: 1907.

PMCID:: PMC6690992

Abstract Article PDF–2.3M

Select item 596587210.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 589142611.

PINK1 autophosphorylation is required for ubiquitin recognition

Shafqat Rasool, Naoto Soya, Luc Truong, Nathalie Croteau, Gergely L Lukacs, Jean‐François Trempe

EMBO Rep. 2018 Apr; 19(4): e44981. Published online 2018 Feb 23. doi: 10.15252/embr.201744981

PMCID:: PMC5891426

Abstract Article PDF–2.9M

Select item 582692612.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 570042013.

Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons

Ping-Yue Pan, Xianting Li, Jing Wang, James Powell, Qian Wang, Yuanxi Zhang, Zhaoyu Chen, Bridget Wicinski, Patrick Hof, Timothy A. Ryan, Zhenyu Yue

J Neurosci. 2017 Nov 22; 37(47): 11366–11376. doi: 10.1523/JNEUROSCI.0964-17.2017

PMCID:: PMC5700420

Abstract Article PDF–2.4M

Select item 567930214.

A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity

Ryan H. Purcell, Camilo Toro, William A. Gahl, Randy A. Hall

Hum Mutat. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Hum Mutat. 2017 Dec; 38(12): 1751–1760. Published online 2017 Sep 20. doi: 10.1002/humu.23336

PMCID:: PMC5679302

Abstract Article PDF–1.3M

Select item 566110415.

Loss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling

Yufu Zhu, Xiang Zhang, Lei Wang, Zhe Ji, Manyi Xie, Xinyu Zhou, Zhiyi Liu, Hengliang Shi, Rutong Yu

J Cell Mol Med. 2017 Nov; 21(11): 2685–2694. Published online 2017 May 4. doi: 10.1111/jcmm.13184

PMCID:: PMC5661104

Abstract Article PDF–3.0M

Select item 553358516.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 553161117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539176118.

Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch

Guillaume Desrochers, Laurent Cappadocia, Mathieu Lussier-Price, Anh-Tien Ton, Riham Ayoubi, Adrian Serohijos, James G. Omichinski, Annie Angers

J Biol Chem. 2017 Apr 14; 292(15): 6325–6338. Published online 2017 Feb 24. doi: 10.1074/jbc.M116.754440

PMCID:: PMC5391761

Abstract Article PDF–3.8M

Select item 508060019.

Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System

John D. Murdoch, Christine M. Rostosky, Sindhuja Gowrisankaran, Amandeep S. Arora, Sandra-Fausia Soukup, Ramon Vidal, Vincenzo Capece, Siona Freytag, Andre Fischer, Patrik Verstreken, Stefan Bonn, Nuno Raimundo, Ira Milosevic

Cell Rep. 2016 Oct 18; 17(4): 1071–1086. Published online 2016 Oct 6. doi: 10.1016/j.celrep.2016.09.058

PMCID:: PMC5080600

Abstract Article

Select item 488668820.

ALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signaling

Vincent Mercier, Marine H. Laporte, Olivier Destaing, Béatrice Blot, Cédric M. Blouin, Karin Pernet-Gallay, Christine Chatellard, Yasmina Saoudi, Corinne Albiges-Rizo, Christophe Lamaze, Sandrine Fraboulet, Anne Petiot, Rémy Sadoul

Sci Rep. 2016; 6: 26986. Published online 2016 May 31. doi: 10.1038/srep26986

PMCID:: PMC4886688

Abstract Article PDF–1.8M

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PMC Links for GEO Profiles (Select 27105255) (61)
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Related Entries for OMIM (Select 610070) (3)
OMIM
serine/threonine-protein kinase PLK4 isoform X3 [Homo sapiens]
serine/threonine-protein kinase PLK4 isoform X3 [Homo sapiens]
gi|530377091|ref|XP_005262758.1|

Protein
serine/threonine-protein kinase PLK4 isoform X2 [Homo sapiens]
serine/threonine-protein kinase PLK4 isoform X2 [Homo sapiens]
gi|1034638167|ref|XP_016863152.1|

Protein

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