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Select item 108792131.

HMGB1 promotes mitochondrial transfer between hepatocellular carcinoma cells through RHOT1 and RAC1 under hypoxia

Mengjia Jing, Xiaofeng Xiong, Xin Mao, Qianben Song, Lumiao Zhang, Yiming Ouyang, Yingzhi Pang, Yu Fu, Wei Yan

Cell Death Dis. 2024 Feb; 15(2): 155. Published online 2024 Feb 20. doi: 10.1038/s41419-024-06536-6

PMCID:: PMC10879213

Abstract Article PDF–6.5M

Select item 107465252.

Interaction between the mitochondrial adaptor MIRO and the motor adaptor TRAK

Elana E. Baltrusaitis, Erika E. Ravitch, Adam R. Fenton, Tania A. Perez, Erika L.F. Holzbaur, Roberto Dominguez

J Biol Chem. 2023 Dec; 299(12): 105441. Published online 2023 Nov 8. doi: 10.1016/j.jbc.2023.105441

PMCID:: PMC10746525

Abstract Article PDF–4.4M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99786354.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 91197366.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90588367.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 89738568.

Hsa_circ_0005230 is up-regulated and promotes gastric cancer cell invasion and migration via regulating the miR-1299/RHOT1 axis

Yan-Yu Peng, Dan Sun, Yan Xin

Bioengineered. 2022; 13(3): 5046–5063. Published online 2022 Feb 16. doi: 10.1080/21655979.2022.2036514

PMCID:: PMC8973856

Abstract Article PDF–2.8M

Select item 88288959.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 856647310.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 855290711.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 843694712.

Circular RNA circRHOT1 contributes to pathogenesis of non-small cell lung cancer by epigenetically enhancing C-MYC expression through recruiting KAT5

Xiaoyan Ren, Jiangang Yu, Lili Guo, Hong Ma

Aging (Albany NY) 2021 Aug 31; 13(16): 20372–20382. Published online 2021 Aug 18. doi: 10.18632/aging.203417

PMCID:: PMC8436947

Abstract Article PDF–1.7M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803494214.

Circular RNA RHOT1 promotes progression and inhibits ferroptosis via mir-106a-5p/STAT3 axis in breast cancer

Huiming Zhang, Zhicheng Ge, Zihan Wang, Yinguang Gao, Yang Wang, Xiang Qu

Aging (Albany NY) 2021 Mar 31; 13(6): 8115–8126. Published online 2021 Mar 3. doi: 10.18632/aging.202608

PMCID:: PMC8034942

Abstract Article PDF–1.1M

Select item 796055015.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

Select item 774435716.

Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase

Kyle P. Smith, Pamela J. Focia, Srinivas Chakravarthy, Eric C. Landahl, Julian L. Klosowiak, Sarah E. Rice, Douglas M. Freymann

J Struct Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Struct Biol. 2020 Dec 1; 212(3): 107656. Published online 2020 Oct 24. doi: 10.1016/j.jsb.2020.107656

PMCID:: PMC7744357

Abstract Article PDF–1.4M

Select item 773619917.

The role of RHOT1 and RHOT2 genetic variation on Parkinson disease risk and onset

María Teresa Periñán, Pilar Gómez-Garre, Cornelis Blauwendraat, Pablo Mir, Sara Bandres-Ciga

Neurobiol Aging. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Neurobiol Aging. 2021 Jan; 97: 144.e1–144.e3. Published online 2020 Jul 14. doi: 10.1016/j.neurobiolaging.2020.07.003

PMCID:: PMC7736199

Abstract Article PDF–459K

Select item 742732718.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 725551919.

Miro: A molecular switch at the center of mitochondrial regulation

Emily L. Eberhardt, Anthony V. Ludlam, Zhenyu Tan, Michael A. Cianfrocco

Protein Sci. 2020 Jun; 29(6): 1269–1284. Published online 2020 Feb 24. doi: 10.1002/pro.3839

PMCID:: PMC7255519

Abstract Article PDF–3.5M

Select item 725485120.

Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease

Clara Berenguer-Escuder, Dajana Grossmann, Paul Antony, Giuseppe Arena, Kobi Wasner, François Massart, Javier Jarazo, Jonas Walter, Jens C Schwamborn, Anne Grünewald, Rejko Krüger

Hum Mol Genet. 2020 May 28; 29(8): 1353–1364. Published online 2020 Apr 13. doi: 10.1093/hmg/ddaa066

PMCID:: PMC7254851

Abstract Article PDF–1.3M

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