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Select item 111583701.

Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung

Jun‐ichiro Ikeda, Tomofumi Oda, Masayoshi Inoue, Takamasa Uekita, Ryuichi Sakai, Meinoshin Okumura, Katsuyuki Aozasa, Eiichi Morii

Cancer Sci. 2009 Mar; 100(3): 429–433. Published online 2008 Dec 11. doi: 10.1111/j.1349-7006.2008.01066.x

PMCID:: PMC11158370

Abstract Article PDF–171K

Select item 99897452.

Metastatic prostate cancer‐derived extracellular vesicles facilitate osteoclastogenesis by transferring the CDCP1 protein

Fumihiko Urabe, Nobuyoshi Kosaka, Yusuke Yamamoto, Kagenori Ito, Kurataka Otsuka, Carolina Soekmadji, Shin Egawa, Takahiro Kimura, Takahiro Ochiya

J Extracell Vesicles. 2023 Mar; 12(3): 12312. Published online 2023 Mar 7. doi: 10.1002/jev2.12312

PMCID:: PMC9989745

Abstract Article PDF–2.3M

Select item 99807593.

CDCP1 (CUB domain containing protein 1) is a potential urine-based biomarker in the diagnosis of low-grade urothelial carcinoma

Chien-Liang Liu, Hung-Wen Tsai, Shu-Ling Peng, Ching-Ping Chang, Yu-Hao Chang, Huei-Sheng Huang

PLoS One. 2023; 18(3): e0281873. Published online 2023 Mar 2. doi: 10.1371/journal.pone.0281873

PMCID:: PMC9980759

Abstract Article PDF–2.0M

Select item 98075634.

CDCP1 expression is frequently increased in aggressive urothelial carcinoma and promotes urothelial tumor progression

Miriam Saponaro, Sina Flottmann, Markus Eckstein, Oliver Hommerding, Niklas Klümper, Dillon Corvino, Sana Hosni, Anja Schmidt, Nicolas Mönig, Doris Schmidt, Jörg Ellinger, Marieta Toma, Glen Kristiansen, Tobias Bald, Andrea Alimonti, Manuel Ritter, Michael Hölzel, Abdullah Alajati

Sci Rep. 2023; 13: 73. Published online 2023 Jan 2. doi: 10.1038/s41598-022-26579-z

Correction in:: Sci Rep. 2023; 13: 2838.

PMCID:: PMC9807563

Abstract Article PDF–4.5M

Select item 88671155.

SRC kinase activator CDCP1 promotes hepatocyte growth factor–induced cell migration/invasion of a subset of breast cancer cells

Naoyuki Kawase, Atsuya Sugihara, Kentaro Kajiwara, Michio Hiroshima, Kanako Akamatsu, Shigeyuki Nada, Kunio Matsumoto, Masahiro Ueda, Masato Okada

J Biol Chem. 2022 Mar; 298(3): 101630. Published online 2022 Jan 24. doi: 10.1016/j.jbc.2022.101630

PMCID:: PMC8867115

Abstract Article PDF–4.8M

Select item 88437436.

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

Shion A. Lim, Jie Zhou, Alexander J. Martinko, Yung-Hua Wang, Ekaterina V. Filippova, Veronica Steri, Donghui Wang, Soumya G. Remesh, Jia Liu, Byron Hann, Anthony A. Kossiakoff, Michael J. Evans, Kevin K. Leung, James A. Wells

J Clin Invest. 2022 Feb 15; 132(4): e154604. Published online 2022 Feb 15. doi: 10.1172/JCI154604

PMCID:: PMC8843743

Abstract Article PDF–2.4M

Select item 86639487.

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm

Weijing Cai, Ranjala Ratnayake, Mengxiong Wang, Qi-Yin Chen, Kevin P. Raisch, Long H. Dang, Brian K. Law, Hendrik Luesch

Curr Res Pharmacol Drug Discov. 2021; 2: 100053. Published online 2021 Sep 8. doi: 10.1016/j.crphar.2021.100053

PMCID:: PMC8663948

Abstract Article PDF–1.9M

Select item 84552028.

Preclinical Molecular PET-CT Imaging Targeting CDCP1 in Colorectal Cancer

Tahleesa J. Cuda, Yaowu He, Thomas Kryza, Tashbib Khan, Brian W. Tse, Kamil A. Sokolowski, Cheng Liu, Nicholas Lyons, Madeline Gough, Cameron E. Snell, David K. Wyld, Stephen Rose, Andrew D. Riddell, Andrew R. L. Stevenson, Paul A. Thomas, David A. Clark, Simon Puttick, John D. Hooper

Contrast Media Mol Imaging. 2021; 2021: 3153278. Published online 2021 Sep 13. doi: 10.1155/2021/3153278

PMCID:: PMC8455202

Abstract Article PDF–3.6M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 793596310.

Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma

Daniel Schäfer, Stefan Tomiuk, Laura N. Küster, Wa’el Al Rawashdeh, Janina Henze, German Tischler-Höhle, David J. Agorku, Janina Brauner, Cathrin Linnartz, Dominik Lock, Andrew Kaiser, Christoph Herbel, Dominik Eckardt, Melina Lamorte, Dorothee Lenhard, Julia Schüler, Philipp Ströbel, Jeannine Missbach-Guentner, Diana Pinkert-Leetsch, Frauke Alves, Andreas Bosio, Olaf Hardt

Nat Commun. 2021; 12: 1453. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21774-4

PMCID:: PMC7935963

Abstract Article PDF–6.6M

Select item 785289011.

An oncogenic viral interferon regulatory factor upregulates CUB domain-containing protein 1 to promote angiogenesis by hijacking transcription factor lymphoid enhancer-binding factor 1 and metastasis suppressor CD82

Wan Li, Qingxia Wang, Xiaoyu Qi, Hongmei Lu, Yuheng Chen, Jiale Shi, Fei Wang, Ziyu Wang, Yao Lu, Zhongmou Lu, Qin Yan, Cong Wang, Shou-Jiang Gao, Chun Lu

Cell Death Differ. 2020 Dec; 27(12): 3289–3306. Published online 2020 Jun 17. doi: 10.1038/s41418-020-0578-0

Correction in:: Cell Death Differ. 2021 May; 28(5): 1754.

PMCID:: PMC7852890

Abstract Article PDF–7.5M

Select item 783501412.

The emerging role of the MiR-1272-ADAM9-CDCP1 signaling pathway in the progression of glioma

Fei Geng, Gui-Feng Lu, Yu-Jun Luo, Sky Dominguez, De-Ying Kong, Lian-Hua Shen, Xiao-Mei Luo, Xin Yang, Min Hu, Wen-Shan Lai, Zhi-Shui Jiang, Yuan-Shou Chen

Aging (Albany NY) 2021 Jan 15; 13(1): 894–909. Published online 2020 Nov 26. doi: 10.18632/aging.202196

PMCID:: PMC7835014

Abstract Article PDF–2.5M

Select item 771257113.

Programmable N6-methyladenosine modification of CDCP1 mRNA by RCas9-methyltransferase like 3 conjugates promotes bladder cancer development

Xiaoling Ying, Xu Jiang, Haiqing Zhang, Bixia Liu, Yapeng Huang, Xiaowei Zhu, Defeng Qi, Gang Yuan, Junhang Luo, Weidong Ji

Mol Cancer. 2020; 19: 169. Published online 2020 Dec 3. doi: 10.1186/s12943-020-01289-0

PMCID:: PMC7712571

Abstract Article PDF–3.1M

Select item 765716714.

Suppression of autophagy by CUB domain‐containing protein 1 signaling is essential for anchorage‐independent survival of lung cancer cells

Takamasa Uekita, Satoko Fujii, Yuri Miyazawa, Akinori Hashiguchi, Hitosi Abe, Michiie Sakamoto, Ryuichi Sakai

Cancer Sci. 2013 Jul; 104(7): 865–870. Published online 2013 Apr 19. doi: 10.1111/cas.12154

PMCID:: PMC7657167

Abstract Article PDF–641K

Select item 761123515.

Prospective identification of elevated circulating CDCP1 in patients years before onset of lung cancer

Sonia Dagnino, Barbara Bodinier, Florence Guida, Karl Smith-Byrne, Dusan Petrovic, Matthew D. Whitaker, Therese Haugdahl Nøst, Claudia Agnoli, Domenico Palli, Carlotta Sacerdote, Salvatore Panico, Rosario Tumino, Matthias B. Schulze, Mikael Johansson, Pekka Keski-Rahkonen, Augustin Scalbert, Paolo Vineis, Mattias Johansson, Torkjel M. Sandanger, Roel C.H. Vermeulen, Marc Chadeau-Hyam

Cancer Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Cancer Res. 2021 Jul 1; 81(13): 3738–3748. Published online 2021 Feb 11. doi: 10.1158/0008-5472.CAN-20-3454

PMCID:: PMC7611235

Abstract Article PDF–2.2M

Select item 747620816.

Increased Plasma Levels of the Co-stimulatory Proteins CDCP1 and SLAMF1 in Patients With Autoimmune Endocrine Diseases

Louise Magnusson, Daniel Espes, Rosaura Casas, Per-Ola Carlsson

Front Immunol. 2020; 11: 1916. Published online 2020 Aug 24. doi: 10.3389/fimmu.2020.01916

PMCID:: PMC7476208

Abstract Article PDF–451K

Select item 739249117.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 719099818.

CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo

Abdullah Alajati, Mariantonietta D’Ambrosio, Martina Troiani, Simone Mosole, Laura Pellegrini, Jingjing Chen, Ajinkya Revandkar, Marco Bolis, Jean-Philippe Theurillat, Ilaria Guccini, Marco Losa, Arianna Calcinotto, Gaston De Bernardis, Emiliano Pasquini, Rocco D’Antuono, Adam Sharp, Ines Figueiredo, Daniel Nava Rodrigues, Jonathan Welti, Veronica Gil, Wei Yuan, Tatjana Vlajnic, Lukas Bubendorf, Giovanna Chiorino, Letizia Gnetti, Verónica Torrano, Arkaitz Carracedo, Laura Camplese, Susumu Hirabayashi, Elena Canato, Gianfranco Pasut, Monica Montopoli, Jan Hendrik Rüschoff, Peter Wild, Holger Moch, Johann De Bono, Andrea Alimonti

J Clin Invest. 2020 May 1; 130(5): 2435–2450. Published online 2020 Apr 6. doi: 10.1172/JCI131133

PMCID:: PMC7190998

Abstract Article PDF–17M

Select item 716998319.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 708636120.

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

Thomas Kryza, Tashbib Khan, Simon Puttick, Chao Li, Kamil A Sokolowski, Brian WC Tse, Tahleesa Cuda, Nicholas Lyons, Madeline Gough, Julia Yin, Ashleigh Parkin, Elena I Deryugina, James P. Quigley, Ruby H. P. Law, James C. Whisstock, Andrew D. Riddell, Andrew P. Barbour, David K. Wyld, Paul A. Thomas, Stephen Rose, Cameron E. Snell, Marina Pajic, Yaowu He, John D. Hooper

Theranostics. 2020; 10(9): 4116–4133. Published online 2020 Mar 4. doi: 10.7150/thno.43589

PMCID:: PMC7086361

Abstract Article PDF–3.3M

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