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Select item 99252031.

Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage

Kyu Yong Cho, Hideaki Miyoshi, Akinobu Nakamura, Andrew S Greenberg, Tatsuya Atsumi

J Atheroscler Thromb. 2023 Feb 1; 30(2): 170–181. Published online 2022 Jun 6. doi: 10.5551/jat.63153

PMCID:: PMC9925203

Abstract Article PDF–6.0M

Select item 97973162.

Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy

Caleigh Mandel-Brehm, Sara E. Vazquez, Christopher Liverman, Mickie Cheng, Zoe Quandt, Andrew F. Kung, Audrey Parent, Brenda Miao, Emmanuel Disse, Christine Cugnet-Anceau, Stéphane Dalle, Elizaveta Orlova, Elena Frolova, Diana Alba, Aaron Michels, Bergithe E. Oftedal, Michail S. Lionakis, Eystein S. Husebye, Anil K. Agarwal, Xilong Li, Chengsong Zhu, Quan Li, Elif Oral, Rebecca Brown, Mark S. Anderson, Abhimanyu Garg, Joseph L. DeRisi

Diabetes. 2023 Jan; 72(1): 59–70. Published online 2022 Jun 16. doi: 10.2337/db21-1172

PMCID:: PMC9797316

Abstract Article PDF–20M

Select item 97436153.

Impact of blood perilipin A levels on obesity and metabolic health

Emmanuel K. Ofori, Bright Selorm Letsu, Seth K. Amponsah, John Ahenkorah, Sandra Crabbe, Genevieve Kwao-Zigah, Sylvester Y. Oppong, Patrick Diaba-Nuhoho, Seth D. Amanquah

BMC Res Notes. 2022; 15: 367. Published online 2022 Dec 12. doi: 10.1186/s13104-022-06261-3

PMCID:: PMC9743615

Abstract Article PDF–645K

Select item 93323114.

Sex-Dependent Mediation of Leptin in the Association of Perilipin Polymorphisms with BMI and Plasma Lipid Levels in Children

Claudia Vales-Villamarín, Jairo Lumpuy-Castillo, Teresa Gavela-Pérez, Olaya de Dios, Iris Pérez-Nadador, Leandro Soriano-Guillén, Carmen Garcés

Nutrients. 2022 Aug; 14(15): 3072. Published online 2022 Jul 26. doi: 10.3390/nu14153072

PMCID:: PMC9332311

Abstract Article PDF–900K

Select item 93165285.

Genetic Association between Different Metabolic Variants in APOA5 and PLIN1 in Type 2 Diabetes Mellitus among the Western Saudi Population: Case-Control Study

Sherin Bakhashab, Tahani Alsulami, Amani M. T. Gusti, Steve Harakeh, Rajaa Al-Raddadi, Wissam A. Alwazani, Huda F. Alshaibi

Genes (Basel) 2022 Jul; 13(7): 1246. Published online 2022 Jul 14. doi: 10.3390/genes13071246

PMCID:: PMC9316528

Abstract Article PDF–240K

Select item 91138016.

PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile

Kashyap A Patel, Shivang Burman, Thomas W Laver, Andrew T Hattersley, Timothy M Frayling, Michael N Weedon

J Clin Endocrinol Metab. 2022 Jun; 107(6): e2318–e2323. Published online 2022 Mar 2. doi: 10.1210/clinem/dgac104

PMCID:: PMC9113801

Abstract Article

Select item 69167957.

Diagnostic Challenge in PLIN1-Associated Familial Partial Lipodystrophy

Isabelle Jéru, Marie-Christine Vantyghem, Elise Bismuth, Pascale Cervera, Sara Barraud, Martine Auclair, Camille Vatier, Olivier Lascols, David B Savage, Corinne Vigouroux, PLIN1-Study Group

J Clin Endocrinol Metab. 2019 Dec; 104(12): 6025–6032. Published online 2019 Jun 27. doi: 10.1210/jc.2019-00849

PMCID:: PMC6916795

Abstract Article

Select item 65896888.

Dual binding motifs underpin the hierarchical association of perilipins1–3 with lipid droplets

Dalila Ajjaji, Kalthoum Ben M'barek, Michael L. Mimmack, Cheryl England, Haya Herscovitz, Liang Dong, Richard G. Kay, Satish Patel, Vladimir Saudek, Donald M. Small, David B. Savage, Abdou Rachid Thiam

Mol Biol Cell. 2019 Mar 1; 30(5): 703–716. doi: 10.1091/mbc.E18-08-0534

PMCID:: PMC6589688

Abstract Article PDF–2.6M

Select item 65317849.

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia

Mol Metab. 2019 Jun; 24: 108–119. Published online 2019 Mar 13. doi: 10.1016/j.molmet.2019.03.001

PMCID:: PMC6531784

Abstract Article PDF–2.4M

Select item 637080910.

Obesity-associated inflammation triggers an autophagy–lysosomal response in adipocytes and causes degradation of perilipin 1

Liping Ju, Junfeng Han, Xiaoyan Zhang, Yujie Deng, Han Yan, Congrong Wang, Xiaohua Li, Shuqin Chen, Miriayi Alimujiang, Xu Li, Qichen Fang, Ying Yang, Weiping Jia

Cell Death Dis. 2019 Feb; 10(2): 121. Published online 2019 Feb 11. doi: 10.1038/s41419-019-1393-8

PMCID:: PMC6370809

Abstract Article PDF–3.6M

Select item 612689011.

PLIN1 Haploinsufficiency Is Not Associated With Lipodystrophy

Thomas W Laver, Kashyap A Patel, Kevin Colclough, Jacqueline Curran, Jane Dale, Nikki Davis, David B Savage, Sarah E Flanagan, Sian Ellard, Andrew T Hattersley, Michael N Weedon

J Clin Endocrinol Metab. 2018 Sep; 103(9): 3225–3230. Published online 2018 Jul 17. doi: 10.1210/jc.2017-02662

PMCID:: PMC6126890

Abstract Article

Select item 601410212.

OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells

Marie Rogne, Dinh-Toi Chu, Thomas M. Küntziger, Maria-Niki Mylonakou, Philippe Collas, Kjetil Tasken

Mol Biol Cell. 2018 Jun 15; 29(12): 1487–1501. doi: 10.1091/mbc.E17-09-0538

PMCID:: PMC6014102

Abstract Article PDF–8.8M

Select item 567810113.

Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes

Jesper S. Hansen, Sofia de Maré, Helena A. Jones, Olga Göransson, Karin Lindkvist-Petersson

Sci Rep. 2017; 7: 15011. Published online 2017 Nov 8. doi: 10.1038/s41598-017-15059-4

PMCID:: PMC5678101

Abstract Article PDF–3.6M

Select item 561495814.

Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells

Lin Wang, Jun Zhou, Shengmin Yan, Guangsheng Lei, Chao-Hung Lee, Xiao-Ming Yin

Sci Rep. 2017; 7: 12307. Published online 2017 Sep 26. doi: 10.1038/s41598-017-12485-2

PMCID:: PMC5614958

Abstract Article PDF–10M

Select item 557895515.

Epigenetic Regulation of PLIN1 in Obese Women and its Relation to Lipolysis

Lucia Bialesova, Agné Kulyté, Paul Petrus, Indranil Sinha, Jurga Laurencikiene, Chunyan Zhao, Karin Dahlman Wright, Peter Arner, Ingrid Dahlman

Sci Rep. 2017; 7: 10152. Published online 2017 Aug 31. doi: 10.1038/s41598-017-09232-y

PMCID:: PMC5578955

Abstract Article PDF–1.5M

Select item 534340916.

Perilipin polymorphisms are risk factors for the development of obesity in adolescents? A case-control study

Yavuz Tokgöz, Ishak Abdurrahman Işık, Soheil Akbari, Tuncay Kume, Oya Sayın, Esra Erdal, Nur Arslan

Lipids Health Dis. 2017; 16: 52. Published online 2017 Mar 9. doi: 10.1186/s12944-017-0440-7

PMCID:: PMC5343409

Abstract Article PDF–319K

Select item 516156317.

Perilipin staining distinguishes between steatosis and non-alcoholic steatohepatitis in adults and children

Rotonya M. Carr, Ravindra Dhir, Kalyankar Mahadev, Megan Comerford, Naga P. Chalasani, Rexford S. Ahima

Clin Gastroenterol Hepatol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2017 Jan; 15(1): 145–147. Published online 2016 Aug 25. doi: 10.1016/j.cgh.2016.08.023

PMCID:: PMC5161563

Article PDF–362K

Select item 480725318.

Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1–3

Emily R. Rowe, Michael L. Mimmack, Antonio D. Barbosa, Afreen Haider, Iona Isaac, Myriam M. Ouberai, Abdou Rachid Thiam, Satish Patel, Vladimir Saudek, Symeon Siniossoglou, David B. Savage

J Biol Chem. 2016 Mar 25; 291(13): 6664–6678. Published online 2016 Jan 7. doi: 10.1074/jbc.M115.691048

Correction in:: J Biol Chem. 2022 Jan; 298(1): 101490.

PMCID:: PMC4807253

Abstract Article PDF–4.7M

Select item 436174419.

Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy

K Kozusko, VHM Tsang, W Bottomley, YH Cho, S Gandotra, ML Mimmack, K Lim, I Isaac, Satish Patel, V Saudek, S O’Rahilly, S Srinivasan, JR Greenfield, I Barroso, LV Campbell, DB Savage

Diabetes. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Diabetes. 2015 Jan; 64(1): 299–310. Published online 2014 Aug 11. doi: 10.2337/db14-0104

PMCID:: PMC4361744

Abstract Article PDF–1.6M

Select item 392566720.

Common Variations in Perilipin Gene, Central Obesity, and Risk of Type 2 diabetes in US Women

Lu Qi, Cuilin Zhang, Andrew Greenberg, Frank B. Hu

Obesity (Silver Spring) Author manuscript; available in PMC 2014 Feb 16.

Published in final edited form as: Obesity (Silver Spring). 2008 May; 16(5): 1061–1065. Published online 2008 Mar 6. doi: 10.1038/oby.2008.26

PMCID:: PMC3925667

Abstract Article PDF–1.1M

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