PMC Links for GEO Profiles (Select 28808282) - PMC

Select item 101885381.

HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylation of GEF-H1 and activating RhoA/LIMK-1/CFL-1

Xiaoqi Han, Siyuan Jiang, Yinmin Gu, Lihua Ding, Enhao Zhao, Dongxing Cao, Xiaodong Wang, Ya Wen, Yongbo Pan, Xin Yan, Liqiang Duan, Minxuan Sun, Tao Zhou, Yajuan Liu, Hongbo Hu, Qinong Ye, Shan Gao

Cell Death Dis. 2023 May; 14(5): 327. Published online 2023 May 16. doi: 10.1038/s41419-023-05849-2

PMCID:: PMC10188538

Abstract Article PDF–5.4M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 69894024.

HUNK phosphorylates EGFR to regulate breast cancer metastasis

Carly B. Williams, Kendall Phelps-Polirer, Ivan P. Dingle, Christina J. Williams, Matthew J. Rhett, Scott T. Eblen, Kent Armeson, Elizabeth G. Hill, Elizabeth S. Yeh

Oncogene. 2020; 39(5): 1112–1124. Published online 2019 Oct 9. doi: 10.1038/s41388-019-1046-5

Correction in:: Oncogene. 2021; 40(20): 3635–3636.

PMCID:: PMC6989402

Abstract Article PDF–3.2M

Select item 68881225.

HUNK Phosphorylates Rubicon to Support Autophagy

Joelle N. Zambrano, Scott T. Eblen, Melissa Abt, J. Matthew Rhett, Robin Muise-Helmericks, Elizabeth S. Yeh

Int J Mol Sci. 2019 Nov; 20(22): 5813. Published online 2019 Nov 19. doi: 10.3390/ijms20225813

PMCID:: PMC6888122

Abstract Article PDF–1.9M

Select item 61666826.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 53924187.

Hormonally Up-regulated Neu-associated Kinase: A novel target for breast cancer progression

Joelle N. Zambrano, Benjamin A. Neely, Elizabeth S. Yeh

Pharmacol Res. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Pharmacol Res. 2017 May; 119: 188–194. Published online 2017 Feb 9. doi: 10.1016/j.phrs.2017.02.007

PMCID:: PMC5392418

Abstract Article PDF–629K

Select item 43428308.

Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors

Elizabeth S. Yeh, Melissa A. Abt, Elizabeth G. Hill

Breast Cancer Res Treat. 2015; 149(1): 91–98. Published online 2014 Dec 17. doi: 10.1007/s10549-014-3227-9

PMCID:: PMC4342830

Abstract Article PDF–1005K

Select item 35610849.

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225

PMCID:: PMC3561084

Abstract Article PDF–1.0M

Select item 351158910.

Genome-Wide Association Study of Generalized Vitiligo in an Isolated European Founder Population Identifies SMOC2, in Close Proximity to IDDM8

Stanca A. Birlea, Katherine Gowan, Pamela R. Fain, Richard A. Spritz

J Invest Dermatol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: J Invest Dermatol. 2010 Mar; 130(3): 798–803. Published online 2009 Nov 5. doi: 10.1038/jid.2009.347

PMCID:: PMC3511589

Abstract Article PDF–1.1M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 307236612.

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

Xueling Sim, Rick Twee-Hee Ong, Chen Suo, Wan-Ting Tay, Jianjun Liu, Daniel Peng-Keat Ng, Michael Boehnke, Kee-Seng Chia, Tien-Yin Wong, Mark Seielstad, Yik-Ying Teo, E-Shyong Tai

PLoS Genet. 2011 Apr; 7(4): e1001363. Published online 2011 Apr 7. doi: 10.1371/journal.pgen.1001363

PMCID:: PMC3072366

Abstract Article PDF–1.0M

Select item 305569413.

Genome-Wide Pharmacogenomic Study of Neurocognition As an Indicator of Antipsychotic Treatment Response in Schizophrenia

Joseph L McClay, Daniel E Adkins, Karolina Åberg, Jozsef Bukszár, Amit N Khachane, Richard S E Keefe, Diana O Perkins, Joseph P McEvoy, T Scott Stroup, Robert E Vann, Patrick M Beardsley, Jeffrey A Lieberman, Patrick F Sullivan, Edwin J C G van den Oord

Neuropsychopharmacology. 2011 Feb; 36(3): 616–626. Published online 2010 Nov 24. doi: 10.1038/npp.2010.193

PMCID:: PMC3055694

Abstract Article PDF–514K

Select item 304939114.

Hunk is required for HER2/neu-induced mammary tumorigenesis

Elizabeth S. Yeh, Thomas W. Yang, Jason J. Jung, Heather P. Gardner, Robert D. Cardiff, Lewis A. Chodosh

J Clin Invest. 2011 Mar 1; 121(3): 866–879. Published online 2011 Feb 14. doi: 10.1172/JCI42928

PMCID:: PMC3049391

Abstract Article PDF–4.3M

Select item 289646415.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 282389016.

HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1

Miguel Quintela-Fandino, Enrico Arpaia, Dirk Brenner, Theo Goh, Faith Au Yeung, Heiko Blaser, Roumiana Alexandrova, Evan F. Lind, Mike W. Tusche, Andrew Wakeham, Pamela S. Ohashi, Tak W. Mak

Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2622–2627. Published online 2010 Jan 22. doi: 10.1073/pnas.0914492107

PMCID:: PMC2823890

Abstract Article PDF–633K

Select item 273488017.

Gerald B. W. Wertheim, Thomas W. Yang, Tien-chi Pan, Anna Ramne, Zhandong Liu, Heather P. Gardner, Katherine D. Dugan, Petra Kristel, Bas Kreike, Marc J. van de Vijver, Robert D. Cardiff, Carol Reynolds, Lewis A. Chodosh

Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37): 15855–15860. Published online 2009 Aug 28. doi: 10.1073/pnas.0906993106

PMCID:: PMC2734880

Abstract Article PDF–1.5M

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