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Select item 112719771.

The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils

Heike Weighardt, Michael Shapiro, Michelle Mayer, Irmgard Förster, Brigitta Stockinger, Nicola Laura Diny

J Leukoc Biol. 2024 Aug; 116(2): 369–378. Published online 2024 May 3. doi: 10.1093/jleuko/qiae105

PMCID:: PMC11271977

Abstract Article PDF–1.1M

Select item 111398932.

Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression

Jong Ho Park, Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin, Jun Wang, Michael R. Collier, Krishna S. Tummala, Anna Mandinova, Nabeel Bardeesy, Yevgeniy R. Semenov, Mari Mino-Kenudson, Shadmehr Demehri

Nat Commun. 2024; 15: 4099. Published online 2024 May 30. doi: 10.1038/s41467-024-48441-8

PMCID:: PMC11139893

Abstract Article PDF–2.6M

Select item 110939693.

ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1

Margaret Solon, Nianfeng Ge, Shannon Hambro, Susan Haller, Jian Jiang, Miriam Baca, Jessica Preston, Allie Maltzman, Katherine E. Wickliffe, Yuxin Liang, Rohit Reja, Dorothee Nickles, Kim Newton, Joshua D. Webster

Cell Death Differ. 2024 May; 31(5): 672–682. Published online 2024 Mar 28. doi: 10.1038/s41418-024-01286-6

PMCID:: PMC11093969

Abstract Article PDF–5.5M

Select item 109811334.

TRIF-IFN-I pathway in Helicobacter-induced gastric cancer in an accelerated murine disease model and patient biopsies

Prerna Bali, Ivonne Lozano-Pope, Jonathan Hernandez, Monica V. Estrada, Maripat Corr, Michael A. Turner, Michael Bouvet, Christopher Benner, Marygorret Obonyo

iScience. 2024 Apr 19; 27(4): 109457. Published online 2024 Mar 8. doi: 10.1016/j.isci.2024.109457

PMCID:: PMC10981133

Abstract Article PDF–6.4M

Select item 107576505.

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

Dmitri I. Kotov, Ophelia V. Lee, Stefan A. Fattinger, Charlotte A. Langner, Jaresley V. Guillen, Joshua M. Peters, Andres Moon, Eileen M. Burd, Kristen C. Witt, Daniel B. Stetson, David L. Jaye, Bryan D. Bryson, Russell E. Vance

Cell. Author manuscript; available in PMC 2023 Dec 30.

Published in final edited form as: Cell. 2023 Dec 7; 186(25): 5536–5553.e22. Published online 2023 Nov 28. doi: 10.1016/j.cell.2023.11.002

PMCID:: PMC10757650

Abstract Article PDF–3.3M

Select item 107338426.

TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation

Hang Zhao, Shaw-Wei Leu, Liyun Shi, Rejmon Dedaj, Gaofeng Zhao, Hari G. Garg, Lianjun Shen, Egil Lien, Katherine A. Fitzgerald, Aviva Shiedlin, Huahao Shen, Deborah A. Quinn, Charles A. Hales

J Immunol. Author manuscript; available in PMC 2023 Dec 21.

Published in final edited form as: J Immunol. 2010 May 1; 184(9): 5308–5314. Published online 2010 Mar 31. doi: 10.4049/jimmunol.1000009

PMCID:: PMC10733842

Abstract Article PDF–1.3M

Select item 104533657.

Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling

Kalee N. Holloway, James C. Douglas, Tonya M. Rafferty, Cynthia J. M. Kane, Paul D. Drew

Cells. 2023 Aug; 12(16): 2109. Published online 2023 Aug 21. doi: 10.3390/cells12162109

PMCID:: PMC10453365

Abstract Article PDF–2.2M

Select item 103512408.

Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs

Aaron Silva–Sanchez, Selene Meza–Perez, Mingyong Liu, Sara L Stone, Leopoldo Flores–Romo, Eric Ubil, Frances E. Lund, Alexander F. Rosenberg, Troy D. Randall

Sci Immunol. Author manuscript; available in PMC 2023 Dec 23.

Published in final edited form as: Sci Immunol. 2023 Jun 23; 8(84): eadc9081. Published online 2023 Jun 16. doi: 10.1126/sciimmunol.adc9081

PMCID:: PMC10351240

Abstract Article PDF–1.7M

Select item 103213189.

A tissue injury sensing and repair pathway distinct from host pathogen defense

Siqi Liu, Yun Ha Hur, Xin Cai, Qian Cong, Yihao Yang, Chiwei Xu, Angelina M. Bilate, Kevin Andrew Uy Gonzales, S. Martina Parigi, Christopher J. Cowley, Brian Hurwitz, Ji-Dung Luo, Tiffany Tseng, Shiri Gur-Cohen, Megan Sribour, Tatiana Omelchenko, John Levorse, Hilda Amalia Pasolli, Craig B. Thompson, Daniel Mucida, Elaine Fuchs

Cell. Author manuscript; available in PMC 2023 Jul 5.

Published in final edited form as: Cell. 2023 May 11; 186(10): 2127–2143.e22. Published online 2023 Apr 24. doi: 10.1016/j.cell.2023.03.031

PMCID:: PMC10321318

Abstract Article PDF–2.7M

Select item 1025881610.

Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function

Md Masud Alam, Yang De, Xiao-Qing Li, Jia Liu, Timothy Carrel Back, Anna Trivett, Baktiar Karim, Denise Barbut, Michael Zasloff, Joost J. Oppenheim

Cell Rep. Author manuscript; available in PMC 2023 Jun 12.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110090. doi: 10.1016/j.celrep.2021.110090

PMCID:: PMC10258816

Abstract Article PDF–1.6M

Select item 1010737311.

Innate and adaptive immunity to transfused allogenic red blood cells in mice requires MyD88

Arielle Soldatenko, Laura R. Hoyt, Lan Xu, Samuele Calabro, Steven M. Lewis, Antonia E. Gallman, Krystalyn E. Hudson, Sean R. Stowell, Chance J. Luckey, James C. Zimring, Dong Liu, Manjula Santhanakrishnan, Jeanne E. Hendrickson, Stephanie C. Eisenbarth

J Immunol. Author manuscript; available in PMC 2023 Apr 17.

Published in final edited form as: J Immunol. 2022 Feb 15; 208(4): 991–997. Published online 2022 Jan 17. doi: 10.4049/jimmunol.2100784

PMCID:: PMC10107373

Abstract Article PDF–1.6M

Select item 985296012.

A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3

Aneel R. Bhagwani, Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil Kelly, Srimathi Bogamuwa, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Stephen Y. Chan, Delphine Gomez, Elena A. Goncharova, Laszlo Farkas

iScience. 2023 Feb 17; 26(2): 105935. Published online 2023 Jan 5. doi: 10.1016/j.isci.2023.105935

PMCID:: PMC9852960

Abstract Article PDF–6.8M

Select item 969212713.

MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages

Allison M. Owen, Liming Luan, Katherine R. Burelbach, Margaret A. McBride, Cody L. Stothers, Olivia A. Boykin, Kalkena Sivanesam, Jessica F. Schaedel, Tazeen K. Patil, Jingbin Wang, Antonio Hernandez, Naeem K. Patil, Edward R. Sherwood, Julia K. Bohannon

Front Immunol. 2022; 13: 1044662. Published online 2022 Nov 11. doi: 10.3389/fimmu.2022.1044662

PMCID:: PMC9692127

Abstract Article PDF–17M

Select item 966905914.

Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury

Julian Roewe, Sarah Walachowski, Arjun Sharma, Kayleigh A. Berthiaume, Christoph Reinhardt, Markus Bosmann

Front Immunol. 2022; 13: 980733. Published online 2022 Nov 3. doi: 10.3389/fimmu.2022.980733

PMCID:: PMC9669059

Abstract Article PDF–6.6M

Select item 947837815.

The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways

Parakkal Jovvian George, Radu Marches, Djamel Nehar-Belaid, Jacques Banchereau, Sara Lustigman

Front Immunol. 2022; 13: 961094. Published online 2022 Sep 2. doi: 10.3389/fimmu.2022.961094

PMCID:: PMC9478378

Abstract Article PDF–2.6M

Select item 944700716.

RIPK3 promotes Mefv expression and pyrin inflammasome activation via modulation of mTOR signaling

Deepika Sharma, Ankit Malik, Arjun Balakrishnan, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti

J Immunol. Author manuscript; available in PMC 2022 Sep 6.

Published in final edited form as: J Immunol. 2020 Nov 15; 205(10): 2778–2785. Published online 2020 Sep 28. doi: 10.4049/jimmunol.2000244

PMCID:: PMC9447007

Abstract Article PDF–1.7M

Select item 934797117.

Antigen Priming with Enantiospecific Cationic Lipid Nanoparticles Induces Potent Antitumor CTL Responses through Novel Induction of a Type I IFN Response

Siva K. Gandhapudi, Martin Ward, John Peyton C. Bush, Frank Bedu-Addo, Greg Conn, Jerold G. Woodward

J Immunol. Author manuscript; available in PMC 2022 Aug 3.

Published in final edited form as: J Immunol. 2019 Jun 15; 202(12): 3524–3536. Published online 2019 May 3. doi: 10.4049/jimmunol.1801634

PMCID:: PMC9347971

Abstract Article PDF–1.2M

Select item 921453518.

ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF

Hayley I. Muendlein, Wilson M. Connolly, Zoie Magri, David Jetton, Irina Smirnova, Alexei Degterev, Siddharth Balachandran, Alexander Poltorak

Proc Natl Acad Sci U S A. 2022 Jun 14; 119(24): e2113872119. Published online 2022 Jun 6. doi: 10.1073/pnas.2113872119

PMCID:: PMC9214535

Abstract Article PDF–3.1M

Select item 916681319.

Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis

Caterina Di Pietro, Hasan H. Öz, Ping-xia Zhang, Ee-chun Cheng, Valentino Martis, Tracey L. Bonfield, Thomas J. Kelley, Ronald Jubin, Abraham Abuchowski, Diane S. Krause, Marie E. Egan, Thomas S. Murray, Emanuela M. Bruscia

Exp Mol Med. 2022 May; 54(5): 639–652. Published online 2022 May 17. doi: 10.1038/s12276-022-00770-8

PMCID:: PMC9166813

Abstract Article PDF–5.8M

Select item 911365220.

TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

Courtney A. Iberg, Jessica Bourque, Ian Fallahee, Sungho Son, Daniel Hawiger

Cell Rep. Author manuscript; available in PMC 2022 May 17.

Published in final edited form as: Cell Rep. 2022 Apr 12; 39(2): 110657. doi: 10.1016/j.celrep.2022.110657

PMCID:: PMC9113652

Abstract Article PDF–2.4M

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