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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106476993.

A Protein–Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20

Ifeoluwapo Matthew Joshua, Meng Lin, Ariestia Mardjuki, Alessandra Mazzola, Thomas Höfken

Int J Mol Sci. 2023 Nov; 24(21): 15916. Published online 2023 Nov 2. doi: 10.3390/ijms242115916

PMCID:: PMC10647699

Abstract Article PDF–5.4M

Select item 102977004.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 98363485.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 96309866.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 85119508.

The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions

Rajaraman Gopalakrishnan, Fred Winston

J Biol Chem. 2021 Oct; 297(4): 101205. Published online 2021 Sep 17. doi: 10.1016/j.jbc.2021.101205

PMCID:: PMC8511950

Abstract Article PDF–3.1M

Select item 81913329.

The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II

Sara Osman, Eusra Mohammad, Michael Lidschreiber, Alexandra Stuetzer, Fanni Laura Bazsó, Kerstin C. Maier, Henning Urlaub, Patrick Cramer

J Biol Chem. 2021 Jan-Jun; 296: 100734. Published online 2021 Apr 30. doi: 10.1016/j.jbc.2021.100734

PMCID:: PMC8191332

Abstract Article PDF–2.6M

Select item 583420210.

The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters

Alicia C. Salinero, Elisabeth R. Knoll, Z. Iris Zhu, David Landsman, M. Joan Curcio, Randall H. Morse

PLoS Genet. 2018 Feb; 14(2): e1007232. Published online 2018 Feb 20. doi: 10.1371/journal.pgen.1007232

PMCID:: PMC5834202

Abstract Article PDF–5.8M

Select item 576535911.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 574066712.

Def1 interacts with TFIIH and modulates RNA polymerase II transcription

Nivedita Damodaren, Trevor Van Eeuwen, Joanna Zamel, Enrique Lin-Shiao, Nir Kalisman, Kenji Murakami

Proc Natl Acad Sci U S A. 2017 Dec 12; 114(50): 13230–13235. Published online 2017 Nov 27. doi: 10.1073/pnas.1707955114

PMCID:: PMC5740667

Abstract Article PDF–1.2M

Select item 558919613.

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

Philip J. Robinson, Michael J. Trnka, David A. Bushnell, Ralph Davis, Pierre-Jean Mattei, Alma L. Burlingame, Roger D. Kornberg

Cell. Author manuscript; available in PMC 2017 Sep 8.

Published in final edited form as: Cell. 2016 Sep 8; 166(6): 1411–1422.e16. doi: 10.1016/j.cell.2016.08.050

PMCID:: PMC5589196

Abstract Article PDF–1.5M

Select item 558778214.

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

Răzvan V. Chereji, Vasudha Bharatula, Nils Elfving, Jeanette Blomberg, Miriam Larsson, Alexandre V. Morozov, James R. Broach, Stefan Björklund

Nucleic Acids Res. 2017 Sep 6; 45(15): 8806–8821. Published online 2017 May 30. doi: 10.1093/nar/gkx491

PMCID:: PMC5587782

Abstract Article PDF–3.5M

Select item 534518215.

Constitutively-stressed yeast strains are high-yielding for recombinant Fps1: implications for the translational regulation of an aquaporin

Stephanie P. Cartwright, Richard A. J. Darby, Debasmita Sarkar, Nicklas Bonander, Stephane R. Gross, Mark P. Ashe, Roslyn M. Bill

Microb Cell Fact. 2017; 16: 41. Published online 2017 Mar 9. doi: 10.1186/s12934-017-0656-2

PMCID:: PMC5345182

Abstract Article PDF–1.3M

Select item 506661716.

Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Thomas Eychenne, Elizaveta Novikova, Marie-Bénédicte Barrault, Olivier Alibert, Claire Boschiero, Nuno Peixeiro, David Cornu, Virginie Redeker, Laurent Kuras, Pierre Nicolas, Michel Werner, Julie Soutourina

Genes Dev. 2016 Sep 15; 30(18): 2119–2132. doi: 10.1101/gad.285775.116

PMCID:: PMC5066617

Abstract Article PDF–1.4M

Select item 474391917.

The Replisome-Coupled E3 Ubiquitin Ligase Rtt101^Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress

Raymond Buser, Vanessa Kellner, Andre Melnik, Caroline Wilson-Zbinden, René Schellhaas, Lisa Kastner, Wojciech Piwko, Martina Dees, Paola Picotti, Marija Maric, Karim Labib, Brian Luke, Matthias Peter

PLoS Genet. 2016 Feb; 12(2): e1005843. Published online 2016 Feb 5. doi: 10.1371/journal.pgen.1005843

PMCID:: PMC4743919

Abstract Article PDF–9.8M

Select item 464423518.

The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression

Maren Schneider, Doris Hellerschmied, Tobias Schubert, Stefan Amlacher, Vinesh Vinayachandran, Rohit Reja, B. Franklin Pugh, Tim Clausen, Alwin Köhler

Cell. 2015 Aug 27; 162(5): 1016–1028. doi: 10.1016/j.cell.2015.07.059

PMCID:: PMC4644235

Abstract Article

Select item 462706619.

Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo

Fanny Eyboulet, Sandra Wydau-Dematteis, Thomas Eychenne, Olivier Alibert, Helen Neil, Claire Boschiero, Marie-Claire Nevers, Hervé Volland, David Cornu, Virginie Redeker, Michel Werner, Julie Soutourina

Nucleic Acids Res. 2015 Oct 30; 43(19): 9214–9231. Published online 2015 Aug 3. doi: 10.1093/nar/gkv782