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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977002.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 92098113.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 83535264.

The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription

David Z. Kochan, Julia S. P. Mawer, Jennifer Massen, Kiril Tishinov, Swati Parekh, Martin Graef, Anne Spang, Peter Tessarz

J Cell Sci. 2021 Aug 1; 134(15): jcs259051. Published online 2021 Aug 5. doi: 10.1242/jcs.259051

PMCID:: PMC8353526

Abstract Article

Select item 81913325.

The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II

Sara Osman, Eusra Mohammad, Michael Lidschreiber, Alexandra Stuetzer, Fanni Laura Bazsó, Kerstin C. Maier, Henning Urlaub, Patrick Cramer

J Biol Chem. 2021 Jan-Jun; 296: 100734. Published online 2021 Apr 30. doi: 10.1016/j.jbc.2021.100734

PMCID:: PMC8191332

Abstract Article PDF–2.6M

Select item 78103846.

Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module

Yi-Chuan Li, Ti-Chun Chao, Hee Jong Kim, Timothy Cholko, Shin-Fu Chen, Guojie Li, Laura Snyder, Kotaro Nakanishi, Chia-en Chang, Kenji Murakami, Benjamin A. Garcia, Thomas G. Boyer, Kuang-Lei Tsai

Sci Adv. 2021 Jan; 7(3): eabd4484. Published online 2021 Jan 15. doi: 10.1126/sciadv.abd4484

PMCID:: PMC7810384

Abstract Article PDF–4.3M

Select item 73467237.

Ubiquitin–proteasome-mediated cyclin C degradation promotes cell survival following nitrogen starvation

Stephen D. Willis, Sara E. Hanley, Thomas Beishke, Prasanna D. Tati, Katrina F. Cooper

Mol Biol Cell. 2020 May 1; 31(10): 1015–1031. doi: 10.1091/mbc.E19-11-0622

PMCID:: PMC7346723

Abstract Article PDF–4.6M

Select item 71383328.

Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis

Yu-Ying Phoebe Hsieh, Vasso Makrantoni, Daniel Robertson, Adèle L. Marston, Andrew W. Murray

PLoS Biol. 2020 Mar; 18(3): e3000635. Published online 2020 Mar 10. doi: 10.1371/journal.pbio.3000635

PMCID:: PMC7138332

Abstract Article PDF–3.6M

Select item 61573539.

Functional Analysis of the Ume3p/Srb11p–RNA Polymerase II Holoenzyme Interaction

Katrina F. Cooper, RANDY STRICH

Gene Expr. 1999; 8(1): 43–57. Published online 2018 Sep 26.

PMCID:: PMC6157353

Abstract Article PDF–5.0M

Select item 599696010.

A complex molecular switch directs stress-induced cyclin C nuclear release through SCF^Grr1-mediated degradation of Med13

David C. Stieg, Stephen D. Willis, Vidyaramanan Ganesan, Kai Li Ong, Joseph Scuorzo, Mia Song, Julianne Grose, Randy Strich, Katrina F. Cooper

Mol Biol Cell. 2018 Feb 1; 29(3): 363–375. doi: 10.1091/mbc.E17-08-0493

PMCID:: PMC5996960

Abstract Article PDF–2.0M

Select item 576535911.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 573630912.

MPK1/SLT2 links multiple stress responses with gene expression in budding yeast by phosphorylating Tyr1 of the RNAP II CTD

Nathan Yurko, Xiaochuan Liu, Takashi Yamazaki, Mainul Hoque, Bin Tian, James L. Manley

Mol Cell. Author manuscript; available in PMC 2018 Dec 7.

Published in final edited form as: Mol Cell. 2017 Dec 7; 68(5): 913–925.e3. doi: 10.1016/j.molcel.2017.11.020

PMCID:: PMC5736309

Abstract Article PDF–1.5M

Select item 566188513.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 558778214.

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

Răzvan V. Chereji, Vasudha Bharatula, Nils Elfving, Jeanette Blomberg, Miriam Larsson, Alexandre V. Morozov, James R. Broach, Stefan Björklund

Nucleic Acids Res. 2017 Sep 6; 45(15): 8806–8821. Published online 2017 May 30. doi: 10.1093/nar/gkx491

PMCID:: PMC5587782

Abstract Article PDF–3.5M

Select item 555170715.

Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates

Stefan Böckler, Xenia Chelius, Nadine Hock, Till Klecker, Madita Wolter, Matthias Weiss, Ralf J. Braun, Benedikt Westermann

J Cell Biol. 2017 Aug 7; 216(8): 2481–2498. doi: 10.1083/jcb.201611197

PMCID:: PMC5551707

Abstract Article PDF–2.8M

Select item 534570116.

The Saccharomyces cerevisiae Cdk8 Mediator Represses AQY1 Transcription by Inhibiting Set1p-Dependent Histone Methylation

Michael J. Law, Michael A. Finger

G3 (Bethesda) 2017 Mar; 7(3): 1001–1010. Published online 2017 Jan 30. doi: 10.1534/g3.117.039586

PMCID:: PMC5345701

Abstract Article PDF–1.7M

Select item 520924517.

A network of conserved synthetic lethal interactions for exploration of precision cancer therapy

Rohith Srivas, John Paul Shen, Chih Cheng Yang, Su Ming Sun, Jianfeng Li, Andrew M. Gross, James Jensen, Katherine Licon, Ana Bojorquez-Gomez, Kristin Klepper, Justin Huang, Daniel Pekin, Jia L. Xu, Huwate Yeerna, Vignesh Sivaganesh, Leonie Kollenstart, Haico van Attikum, Pedro Aza-Blanc, Robert W. Sobol, Trey Ideker

Mol Cell. Author manuscript; available in PMC 2017 Aug 4.

Published in final edited form as: Mol Cell. 2016 Aug 4; 63(3): 514–525. Published online 2016 Jul 21. doi: 10.1016/j.molcel.2016.06.022

PMCID:: PMC5209245

Abstract Article PDF–1.6M

Select item 505508318.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 487539819.

Structural flexibility and functional interaction of mediator Cdk8 module

Xuejuan Wang, Jianye Wang, Zhenrui Ding, Jinhua Ji, Qianqian Sun, Gang Cai

Protein Cell. 2013 Dec; 4(12): 911–920. Published online 2013 Sep 16. doi: 10.1007/s13238-013-3069-y

PMCID:: PMC4875398

Abstract Article PDF–2.0M

Select item 466488220.

Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated

Natalia S. Voynova, Carole Roubaty, Hector M. Vazquez, Shamroop K. Mallela, Christer S. Ejsing, Andreas Conzelmann

Eukaryot Cell. 2015 Dec; 14(12): 1203–1216. Prepublished online 2015 Oct 2. Published online 2015 Nov 30. doi: 10.1128/EC.00117-15

PMCID:: PMC4664882

Abstract Article PDF–2.3M

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