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Select item 112946051.

Receptor-mediated cargo hitchhiking on bulk autophagy

Eigo Takeda, Takahiro Isoda, Sachiko Hosokawa, Yu Oikawa, Shukun Hotta-Ren, Alexander I May, Yoshinori Ohsumi

EMBO J. 2024 Aug; 43(15): 3116–3140. Published online 2024 May 16. doi: 10.1038/s44318-024-00091-8

PMCID:: PMC11294605

Abstract Article PDF–5.6M

Select item 110016342.

Restricted glycolysis is a primary cause of the reduced growth rate of zinc-deficient yeast cells

Colin W. MacDiarmid, Janet Taggart, Michael Kubisiak, David J. Eide

J Biol Chem. 2024 Apr; 300(4): 107147. Published online 2024 Mar 7. doi: 10.1016/j.jbc.2024.107147

PMCID:: PMC11001634

Abstract Article PDF–2.2M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333684.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 83006476.

Effects of Serine or Threonine in the Active Site of Typical 2-Cys Prx on Hyperoxidation Susceptibility and on Chaperone Activity

Carlos A. Tairum, Melina Cardoso Santos, Carlos Alexandre Breyer, Ana Laura Pires de Oliveira, Vitoria Isabela Montanhero Cabrera, Guilherme Toledo-Silva, Gustavo Maruyama Mori, Marcos Hikari Toyama, Luis Eduardo Soares Netto, Marcos Antonio de Oliveira

Antioxidants (Basel) 2021 Jul; 10(7): 1032. Published online 2021 Jun 25. doi: 10.3390/antiox10071032

PMCID:: PMC8300647

Abstract Article PDF–4.7M

Select item 70362847.

Aromatic Residues at the Dimer–Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function

Matthew A. Loberg, Jennifer E. Hurtig, Aaron H. Graff, Kristin M. Allan, John A. Buchan, Matthew K. Spencer, Joseph E. Kelly, Jill E. Clodfelter, Kevin A. Morano, W. Todd Lowther, James D. West

Chem Res Toxicol. Author manuscript; available in PMC 2020 Feb 23.

Published in final edited form as: Chem Res Toxicol. 2019 Mar 18; 32(3): 474–483. Published online 2019 Feb 11. doi: 10.1021/acs.chemrestox.8b00346

PMCID:: PMC7036284

Abstract Article PDF–1.9M

Select item 67454958.

Hyperoxidation of mitochondrial peroxiredoxin limits H₂O₂‐induced cell death in yeast

Gaetano Calabrese, Esra Peker, Prince Saforo Amponsah, Michaela Nicole Hoehne, Trine Riemer, Marie Mai, Gerd Patrick Bienert, Marcel Deponte, Bruce Morgan, Jan Riemer

EMBO J. 2019 Sep 16; 38(18): e101552. Published online 2019 Aug 7. doi: 10.15252/embj.2019101552

PMCID:: PMC6745495

Abstract Article PDF–3.4M

Select item 66890869.

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range

Hannah Girstmair, Franziska Tippel, Abraham Lopez, Katarzyna Tych, Frank Stein, Per Haberkant, Philipp Werner Norbert Schmid, Dominic Helm, Matthias Rief, Michael Sattler, Johannes Buchner

Nat Commun. 2019; 10: 3626. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11518-w

PMCID:: PMC6689086

Abstract Article PDF–2.3M

Select item 607844410.

Endoplasmic reticulum (ER) stress–induced reactive oxygen species (ROS) are detrimental for the fitness of a thioredoxin reductase mutant

Paraskevi Kritsiligkou, Jonathan D. Rand, Alan J. Weids, Ximeng Wang, Chris J. Kershaw, Chris M. Grant

J Biol Chem. 2018 Aug 3; 293(31): 11984–11995. Published online 2018 Jun 5. doi: 10.1074/jbc.RA118.001824

PMCID:: PMC6078444

Abstract Article PDF–1.8M

Select item 576535911.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 566188512.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 560025413.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 559294514.

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark

G3 (Bethesda) 2017 Sep; 7(9): 3203–3215. Published online 2017 Jul 28. doi: 10.1534/g3.117.300089

PMCID:: PMC5592945

Abstract Article PDF–1.7M

Select item 543825115.

Nonlinear feedback drives homeostatic plasticity in H₂O₂ stress response

Youlian Goulev, Sandrine Morlot, Audrey Matifas, Bo Huang, Mikael Molin, Michel B Toledano, Gilles Charvin

eLife. 2017; 6: e23971. Published online 2017 Apr 18. doi: 10.7554/eLife.23971

PMCID:: PMC5438251

Abstract Article PDF–4.6M

Select item 539389616.

Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI⁺] prion formation

Shaun H. Speldewinde, Victoria A. Doronina, Mick F. Tuite, Chris M. Grant

PLoS Genet. 2017 Apr; 13(4): e1006708. Published online 2017 Apr 3. doi: 10.1371/journal.pgen.1006708

PMCID:: PMC5393896

Abstract Article PDF–3.6M

Select item 515480317.

Trapping Redox Partnerships in Oxidant-Sensitive Proteins with a Small, Thiol-Reactive Cross-Linker

Kristin M. Allan, Matthew A. Loberg, Juliet Chepngeno, Jennifer E. Hurtig, Susmit Tripathi, Min Goo Kang, Jonathan K. Allotey, Afton H. Widdershins, Jennifer M. Pilat, Herbert J. Sizek, Wesley J. Murphy, Matthew R. Naticchia, Joseph B. David, Kevin A. Morano, James D. West

Free Radic Biol Med. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Free Radic Biol Med. 2016 Dec; 101: 356–366. Published online 2016 Nov 2. doi: 10.1016/j.freeradbiomed.2016.10.506

PMCID:: PMC5154803

Abstract Article PDF–1.1M

Select item 502585718.

Redox-dependent Regulation of Gluconeogenesis by a Novel Mechanism Mediated by a Peroxidatic Cysteine of Peroxiredoxin

Hayato Irokawa, Tsuyoshi Tachibana, Toshihiko Watanabe, Yuka Matsuyama, Hozumi Motohashi, Ayako Ogasawara, Kenta Iwai, Akira Naganuma, Shusuke Kuge

Sci Rep. 2016; 6: 33536. Published online 2016 Sep 16. doi: 10.1038/srep33536

PMCID:: PMC5025857

Abstract Article PDF–2.7M

Select item 502410319.

Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms

Carlos A. Tairum, Melina Cardoso Santos, Carlos A. Breyer, R. Ryan Geyer, Cecilia J. Nieves, Stephanie Portillo-Ledesma, Gerardo Ferrer-Sueta, José Carlos Toledo, Jr., Marcos H. Toyama, Ohara Augusto, Luis E. S. Netto, Marcos A. de Oliveira

Sci Rep. 2016; 6: 33133. Published online 2016 Sep 15. doi: 10.1038/srep33133

PMCID:: PMC5024103

Abstract Article PDF–1.3M

Select item 490554720.

Chromosome-Specific and Global Effects of Aneuploidy in Saccharomyces cerevisiae

Stacie E. Dodgson, Sharon Kim, Michael Costanzo, Anastasia Baryshnikova, Darcy L. Morse, Chris A. Kaiser, Charles Boone, Angelika Amon

Genetics. 2016 Apr; 202(4): 1395–1409. Published online 2016 Jan 29. doi: 10.1534/genetics.115.185660

PMCID:: PMC4905547

Abstract Article PDF–4.0M

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