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Select item 109424671.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 107672382.

Aldo-keto reductase family member C3 (AKR1C3) promotes hepatocellular carcinoma cell growth by producing prostaglandin F2α

KUO-SHYANG JENG, PO-YU CHENG, YUEH-HSIEN LIN, PO-CHUN LIU, PING-HUI TSENG, YU-CHAO WANG, CHIUNG-FANG CHANG, CHUEN-MIIN LEU

Oncol Res. 2024; 32(1): 163–174. Published online 2023 Nov 15. doi: 10.32604/or.2023.030975

PMCID:: PMC10767238

Abstract Article PDF–6.5M

Select item 106715213.

Keratinocytes Exposed to Blue or Red Light: Proteomic Characterization Showed Cytoplasmic Thioredoxin Reductase 1 and Aldo-Keto Reductase Family 1 Member C3 Triggered Expression

Raffaella Lazzarini, Maria Fiorella Tartaglione, Veronica Ciarapica, Francesco Piva, Matteo Giulietti, Gianluca Fulgenzi, Margherita Martelli, Caterina Ledda, Ermanno Vitale, Marco Malavolta, Lory Santarelli, Massimo Bracci

Int J Mol Sci. 2023 Nov; 24(22): 16189. Published online 2023 Nov 10. doi: 10.3390/ijms242216189

PMCID:: PMC10671521

Abstract Article PDF–4.8M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100037535.

Establishing a Proteomics-Based Signature of AKR1C3-Related Genes for Predicting the Prognosis of Prostate Cancer

Xiaoli Cui, Changcheng Li, Jipeng Ding, Zhou Yao, Tianyu Zhao, Jiahui Guo, Yaru Wang, Jing Li

Int J Mol Sci. 2023 Mar; 24(5): 4513. Published online 2023 Feb 24. doi: 10.3390/ijms24054513

PMCID:: PMC10003753

Abstract Article PDF–8.8M

Select item 99683136.

Influence of aldo–keto reductase 1C3 polymorphisms in early-onset female psoriasis patients

Yuka Nojiri, Motoki Nakamura, Tetsuya Magara, Aya Yamamoto, Kyoko Ikumi, Reiko Nakamura, Emi Nishida, Thomas Haarmann-Stemmann, Akimichi Morita

Sci Rep. 2023; 13: 3280. Published online 2023 Feb 25. doi: 10.1038/s41598-023-30464-8

PMCID:: PMC9968313

Abstract Article PDF–6.1M

Select item 97725587.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 97065858.

AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy

Changqing Wu, Chaoliu Dai, Xinyu Li, Mingju Sun, Hongwei Chu, Qiuhui Xuan, Yalei Yin, Chengnan Fang, Fan Yang, Zhonghao Jiang, Qing Lv, Keqing He, Yiying Qu, Baofeng Zhao, Ke Cai, Shuijun Zhang, Ran Sun, Guowang Xu, Lihua Zhang, Siyu Sun, Yang Liu

Theranostics. 2022; 12(18): 7681–7698. Published online 2022 Nov 7. doi: 10.7150/thno.74974

PMCID:: PMC9706585

Abstract Article PDF–3.0M

Select item 96759789.

Characterization of the major single nucleotide polymorphic variants of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase)

Andrea J. Detlefsen, Phumvadee Wangtrakuldee, Trevor M. Penning

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2022 Jul; 221: 106121. Published online 2022 Apr 28. doi: 10.1016/j.jsbmb.2022.106121

PMCID:: PMC9675978

Abstract Article PDF–1.0M

Select item 963231410.

Plasma Exosomal AKR1C3 mRNA Expression Is a Predictive and Prognostic Biomarker in Patients with Metastatic Castration-Resistant Prostate Cancer

Sha Zhu, Yuchao Ni, Zilin Wang, Xingming Zhang, Yaowen Zhang, Fengnian Zhao, Jindong Dai, Zhipeng Wang, Xudong Zhu, Junru Chen, Jinge Zhao, Yuhao Zeng, Ni Chen, Peng Zeng, Pengfei Shen, Guangxi Sun, Hao Zeng

Oncologist. 2022 Nov; 27(11): e870–e877. Published online 2022 Sep 6. doi: 10.1093/oncolo/oyac177

PMCID:: PMC9632314

Abstract Article PDF–5.2M

Select item 934857611.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928512.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 917548213.

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression

Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma

BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4

PMCID:: PMC9175482

Abstract Article PDF–15M

Select item 874208114.

Assessment of factors associated with PSA level in prostate cancer cases and controls from three geographical regions

Nishi Karunasinghe, Tsion Zewdu Minas, Bo-Ying Bao, Arier Lee, Alice Wang, Shuotun Zhu, Jonathan Masters, Megan Goudie, Shu-Pin Huang, Frank J. Jenkins, Lynnette R. Ferguson

Sci Rep. 2022; 12: 55. Published online 2022 Jan 7. doi: 10.1038/s41598-021-04116-8

PMCID:: PMC8742081

Abstract Article PDF–1.2M

Select item 862362715.

Transcriptomic Profiling Reveals AKR1C1 and AKR1C3 Mediate Cisplatin Resistance in Signet Ring Cell Gastric Carcinoma via Autophagic Cell Death

Nang Lae Lae Phoo, Pornngarm Dejkriengkraikul, Patompong Khaw-On, Supachai Yodkeeree

Int J Mol Sci. 2021 Nov; 22(22): 12512. Published online 2021 Nov 19. doi: 10.3390/ijms222212512

PMCID:: PMC8623627

Abstract Article PDF–6.5M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011