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Select item 108781531.

METTL16 suppressed the proliferation and cisplatin-chemoresistance of bladder cancer by degrading PMEPA1 mRNA in a m6A manner through autophagy pathway

Hao Yu, Juntao Zhuang, Zijian Zhou, Qiang Song, Jiancheng Lv, Xiao Yang, Haiwei Yang, Qiang Lu

Int J Biol Sci. 2024; 20(4): 1471–1491. Published online 2024 Feb 4. doi: 10.7150/ijbs.86719

PMCID:: PMC10878153

Abstract Article PDF–9.0M

Select item 98519732.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 92316233.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 90459814.

PMEPA1 Serves as a Prognostic Biomarker and Correlates with Immune Infiltrates in Cervical Cancer

Jing Li, Wei-min Kong

J Immunol Res. 2022; 2022: 4510462. Published online 2022 Apr 20. doi: 10.1155/2022/4510462

PMCID:: PMC9045981

Abstract Article PDF–3.8M

Select item 85822465.

PMEPA1 Is a Prognostic Biomarker That Correlates With Cell Malignancy and the Tumor Microenvironment in Bladder Cancer

Dongxu Qiu, Jian Hu, Jiao Hu, Anze Yu, Belaydi Othmane, Tongchen He, Jian Ding, Xu Cheng, Wenbiao Ren, Xiyan Tan, Qiaoyan Yu, Jinbo Chen, Xiongbing Zu

Front Immunol. 2021; 12: 705086. Published online 2021 Oct 28. doi: 10.3389/fimmu.2021.705086

PMCID:: PMC8582246

Abstract Article PDF–61M

Select item 85081166.

PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells

Md. Anwarul Haque, Mohammed Abdelaziz, Meidi Utami Puteri, Thanh Thao Vo Nguyen, Kosei Kudo, Yukihide Watanabe, Mitsuyasu Kato

Cancers (Basel) 2021 Oct; 13(19): 4934. Published online 2021 Sep 30. doi: 10.3390/cancers13194934

PMCID:: PMC8508116

Abstract Article PDF–7.4M

Select item 83124687.

Linc00941 regulates esophageal squamous cell carcinoma via functioning as a competing endogenous RNA for miR-877-3p to modulate PMEPA1 expression

Yan Zhang, Huayun Zhu, Ning Sun, Xiaomei Zhang, Geyu Liang, Jiali Zhu, Lei Xia, Yingying Kou, Jianwei Lu

Aging (Albany NY) 2021 Jul 15; 13(13): 17830–17846. Published online 2021 Jul 13. doi: 10.18632/aging.203286

PMCID:: PMC8312468

Abstract Article PDF–1.7M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75651929.

PMEPA1 Gene Isoforms: A Potential Biomarker and Therapeutic Target in Prostate Cancer

Shashwat Sharad, Albert Dobi, Shiv Srivastava, Alagarsamy Srinivasan, Hua Li

Biomolecules. 2020 Sep; 10(9): 1221. Published online 2020 Aug 22. doi: 10.3390/biom10091221

PMCID:: PMC7565192

Abstract Article PDF–2.4M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 698940311.

PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1

Jianxiong Ji, Kaikai Ding, Tao Luo, Ran Xu, Xin Zhang, Bin Huang, Anjing Chen, Di Zhang, Hrvoje Miletic, Rolf Bjerkvig, Frits Thorsen, Jian Wang, Xingang Li

Oncogene. 2020; 39(5): 1125–1139. Published online 2019 Oct 11. doi: 10.1038/s41388-019-1050-9

PMCID:: PMC6989403

Abstract Article PDF–4.5M

Select item 652894312.

2‐(2‐nitrobenzylidene) indolin‐3‐one compound inhibits transmembrane prostate androgen‐induced protein (TMEPAI) expression and cancer cell proliferation

Yuyin Li, Jianjun Wang, Ning Song, Feihong Zeng, Miaomiao Zhao, Ali Wang, Yue Chen, Lei Jing, Peng Yu, Aipo Diao

Cell Prolif. 2018 Oct; 51(5): e12469. Published online 2018 Aug 2. doi: 10.1111/cpr.12469

PMCID:: PMC6528943

Abstract Article PDF–1.2M

Select item 649682613.

Sp1 transcription factor promotes TMEPAI gene expression and contributes to cell proliferation

Yuyin Li, Ailong Guo, Yajuan Feng, Yueying Zhang, Jianjun Wang, Lifang Jing, Yali Yan, Lei Jing, Zhenxing Liu, Long Ma, Aipo Diao

Cell Prolif. 2016 Dec; 49(6): 710–719. Published online 2016 Sep 14. doi: 10.1111/cpr.12292

PMCID:: PMC6496826

Abstract Article PDF–916K

Select item 648441414.

PMEPA1 induces EMT via a non‐canonical TGF‐β signalling in colorectal cancer

Lei Zhang, Xue Wang, Chong Lai, Honghe Zhang, Maode Lai

J Cell Mol Med. 2019 May; 23(5): 3603–3615. Published online 2019 Mar 19. doi: 10.1111/jcmm.14261

PMCID:: PMC6484414

Abstract Article PDF–1.5M

Select item 627571215.

High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone

Yoshifumi S. Hirokawa, Akimitsu Takagi, Katsunori Uchida, Yuji Kozuka, Misao Yoneda, Masatoshi Watanabe, Taizo Shiraishi

Cell Mol Biol Lett. 2007 Sep; 12(3): 370–377. Published online 2007 Feb 23. doi: 10.2478/s11658-007-0009-y

PMCID:: PMC6275712

Summary PDF–608K

Select item 616668216.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 602391917.

High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2

Marisa Cappella, Alessandra Perfetti, Beatrice Cardinali, Jose Manuel Garcia-Manteiga, Matteo Carrara, Claudia Provenzano, Paola Fuschi, Rosanna Cardani, Laura Valentina Renna, Giovanni Meola, Germana Falcone, Fabio Martelli

Cell Death Dis. 2018 Jul; 9(7): 729. Published online 2018 Jun 28. doi: 10.1038/s41419-018-0769-5

PMCID:: PMC6023919

Abstract Article PDF–1.2M

Select item 591246818.

The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor

Yanyun Du, Yan Liu, Yujia Xu, Jiaxiang Juan, Zubin Zhang, Zhuan Xu, Biyin Cao, Qi Wang, Yuanying Zeng, Xinliang Mao

J Biol Chem. 2018 Apr 20; 293(16): 5847–5859. Published online 2018 Feb 21. doi: 10.1074/jbc.RA117.000972

PMCID:: PMC5912468

Abstract Article PDF–3.3M

Select item 567858119.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 531698920.

Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking

Shenheng Luo, Lei Jing, Tian Zhao, Yuyin Li, Zhenxing Liu, Aipo Diao

Sci Rep. 2017; 7: 42668. Published online 2017 Feb 20. doi: 10.1038/srep42668

PMCID:: PMC5316989

Abstract Article PDF–1.7M

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