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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 94115922.

Specificity of TGF-β1 signal designated by LRRC33 and integrin α_Vβ₈

Zelin Duan, Xuezhen Lin, Lixia Wang, Qiuxin Zhen, Yuefeng Jiang, Chuxin Chen, Jing Yang, Chia-Hsueh Lee, Yan Qin, Ying Li, Bo Zhao, Jianchuan Wang, Zhe Zhang

Nat Commun. 2022; 13: 4988. Published online 2022 Aug 25. doi: 10.1038/s41467-022-32655-9

PMCID:: PMC9411592

Abstract Article PDF–10M

Select item 93485763.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92346484.

Integrin subunit beta 8 contributes to lenvatinib resistance in HCC

Wei Hou, Bryan Bridgeman, Greg Malnassy, Xianzhong Ding, Scott J. Cotler, Asha Dhanarajan, Wei Qiu

Hepatol Commun. 2022 Jul; 6(7): 1786–1802. Published online 2022 Mar 3. doi: 10.1002/hep4.1928

PMCID:: PMC9234648

Abstract Article PDF–53M

Select item 92316235.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91778646.

Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma

Yang Liu, Xiangdong Xu, Yuxuan Zhang, Yunzhao Mo, Xinlin Sun, Lingling Shu, Yiquan Ke

Cell Death Dis. 2022 Jun; 13(6): 536. Published online 2022 Jun 8. doi: 10.1038/s41419-022-04959-7

PMCID:: PMC9177864

Abstract Article PDF–9.6M

Select item 88970227.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88219348.

lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Xiaoting Lin, Shiwen Zhuang, Xue Chen, Jun Du, Longhua Zhong, Jiancheng Ding, Lei Wang, Jia Yi, Guosheng Hu, Guohui Tang, Xi Luo, Wen Liu, Feng Ye

Mol Ther. 2022 Feb 2; 30(2): 688–702. Published online 2021 Aug 8. doi: 10.1016/j.ymthe.2021.08.011

PMCID:: PMC8821934

Abstract Article PDF–3.9M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 732206710.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 688949011.

General structural features that regulate integrin affinity revealed by atypical αVβ8

Jianchuan Wang, Yang Su, Roxana E. Iacob, John R. Engen, Timothy A. Springer

Nat Commun. 2019; 10: 5481. Published online 2019 Dec 2. doi: 10.1038/s41467-019-13248-5

PMCID:: PMC6889490

Abstract Article PDF–3.0M

Select item 678143012.

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Kuniyuki Nakamura, Tomoko Ikeuchi, Kazuki Nara, Craig S. Rhodes, Peipei Zhang, Yuta Chiba, Saiko Kazuno, Yoshiki Miura, Tetsuro Ago, Eri Arikawa-Hirasawa, Yoh-suke Mukouyama, Yoshihiko Yamada

J Cell Biol. 2019 Oct 7; 218(10): 3506–3525. Published online 2019 Sep 20. doi: 10.1083/jcb.201807178

PMCID:: PMC6781430

Abstract Article PDF–5.3M

Select item 629979213.

Integrin Subunit beta 8 (ITGB8) Upregulation Is an Independent Predictor of Unfavorable Survival of High-Grade Serous Ovarian Carcinoma Patients

Jing He, Yan Liu, Lixia Zhang, Hongwei Zhang

Med Sci Monit. 2018; 24: 8933–8940. Published online 2018 Dec 10. doi: 10.12659/MSM.911518

PMCID:: PMC6299792

Abstract Article PDF–1.2M

Select item 621484314.

Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension

Anthony Cormier, Melody G. Campbell, Saburo Ito, Shenping Wu, Jianlong Lou, James Marks, Jody Baron, Stephen L. Nishimura, Yifan Cheng

Nat Struct Mol Biol. Author manuscript; available in PMC 2019 Jan 30.

Published in final edited form as: Nat Struct Mol Biol. 2018 Aug; 25(8): 698–704. Published online 2018 Jul 30. doi: 10.1038/s41594-018-0093-x

PMCID:: PMC6214843

Abstract Article PDF–1.0M

Select item 619728715.

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II

Yujing Li, Yunhua Liu, Hanchen Xu, Guanglong Jiang, Kevin Van der Jeught, Yuanzhang Fang, Zhuolong Zhou, Lu Zhang, Michael Frieden, Lifei Wang, Zhenhua Luo, Milan Radovich, Bryan P. Schneider, Yibin Deng, Yunlong Liu, Kun Huang, Bin He, Jin Wang, Xiaoming He, Xinna Zhang, Guang Ji, Xiongbin Lu

Nat Commun. 2018; 9: 4394. Published online 2018 Oct 22. doi: 10.1038/s41467-018-06811-z

PMCID:: PMC6197287

Abstract Article PDF–1.9M

Select item 586840116.

miR-199a-3p enhances cisplatin sensitivity of ovarian cancer cells by targeting ITGB8

Yajie Cui, Fengqin Wu, Defu Tian, Ting Wang, Tianjie Lu, Xiying Huang, Peilian Zhang, Li Qin

Oncol Rep. 2018 Apr; 39(4): 1649–1657. Published online 2018 Feb 12. doi: 10.3892/or.2018.6259

PMCID:: PMC5868401

Abstract Article PDF–1.4M

Select item 582692617.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 544820719.

Atypical interactions of integrin α_Vβ₈ with pro-TGF-β1

Jianchuan Wang, Xianchi Dong, Bo Zhao, Jing Li, Chafen Lu, Timothy A. Springer

Proc Natl Acad Sci U S A. 2017 May 23; 114(21): E4168–E4174. Published online 2017 May 8. doi: 10.1073/pnas.1705129114

PMCID:: PMC5448207

Abstract Article PDF–1.8M

Select item 543951620.

Inflammatory cues enhance TGFß activation by distinct subsets of human intestinal dendritic cells via integrin avß8

TM Fenton, A Kelly, EE Shuttleworth, C Smedley, A Atakilit, F Powrie, S Campbell, SL Nishimura, D Sheppard, S Levison, JJ Worthington, MJ Lehtinen, MA Travis

Mucosal Immunol. Author manuscript; available in PMC 2017 May 22.

Published in final edited form as: Mucosal Immunol. 2017 May; 10(3): 624–634. Published online 2016 Oct 26. doi: 10.1038/mi.2016.94

PMCID:: PMC5439516

Abstract Article PDF–1.3M

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PMC Links for GEO Profiles (Select 33635271) (49)
PMC
Homo sapiens C-type lectin domain family 4 member M (CLEC4M), transcript variant...
Homo sapiens C-type lectin domain family 4 member M (CLEC4M), transcript variant 2, mRNA
gi|1676439855|ref|NM_001144904.2|

Nucleotide
maturase K, partial (chloroplast) [Myroxylon balsamum]
maturase K, partial (chloroplast) [Myroxylon balsamum]
gi|2695720473|gb|WWV79105.1|

Protein
RecName: Full=Bowman-birk type proteinase inhibitor; AltName: Full=TaTI
RecName: Full=Bowman-birk type proteinase inhibitor; AltName: Full=TaTI
gi|25453051|sp|P83284.1|IBB1_AMBAC

Protein

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