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Select item 109424671.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 106415242.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99448894.

Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP

Chao Xiong, Li-Na Jia, Wei-Xi Xiong, Xin-Tong Wu, Liu-Lin Xiong, Ting-Hua Wang, Dong Zhou, Zhen Hong, Zheng Liu, Lin Tang

Signal Transduct Target Ther. 2023; 8: 74. Published online 2023 Feb 22. doi: 10.1038/s41392-022-01280-9

PMCID:: PMC9944889

Abstract Article PDF–4.7M

Select item 96837915.

Structural and functional insights of the human peroxisomal ABC transporter ALDP

Yutian Jia, Yanming Zhang, Wenhao Wang, Jianlin Lei, Zhengxin Ying, Guanghui Yang

eLife. 2022; 11: e75039. Published online 2022 Nov 14. doi: 10.7554/eLife.75039

PMCID:: PMC9683791

Abstract Article PDF–5.5M

Select item 93383136.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 92626147.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92581328.

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants

Laura Strohm, Zehan Hu, Yongwon Suk, Alina Rühmkorf, Erin Sternburg, Vanessa Gattringer, Henrick Riemenschneider, Riccardo Berutti, Elisabeth Graf, Jochen H Weishaupt, Monika S Brill, Angelika B Harbauer, Dorothee Dormann, Jörn Dengjel, Dieter Edbauer, Christian Behrends

Life Sci Alliance. 2022 Nov; 5(11): e202101327. Published online 2022 Jul 1. doi: 10.26508/lsa.202101327

PMCID:: PMC9258132

Abstract Article PDF–5.9M

Select item 91775979.

Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1

Zhi-Peng Chen, Da Xu, Liang Wang, Yao-Xu Mao, Yang Li, Meng-Ting Cheng, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen

Nat Commun. 2022; 13: 3299. Published online 2022 Jun 8. doi: 10.1038/s41467-022-30974-5

PMCID:: PMC9177597

Abstract Article PDF–2.9M

Select item 898059310.

Drug discovery for X-linked adrenoleukodystrophy: An unbiased screen for compounds that lower very long-chain fatty acids

Ann B. Moser, Yanqiu Liu, Xiaohai Shi, Ulrike Schrifl, Shandi Hiebler, Ali Fatemi, Nancy E. Braverman, Steven J. Steinberg, Paul A. Watkins

J Cell Biochem. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: J Cell Biochem. 2021 Oct; 122(10): 1337–1349. Published online 2021 May 30. doi: 10.1002/jcb.30014

PMCID:: PMC8980593

Abstract Article PDF–940K

Select item 895660411.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 880778612.

Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1

Rong Wang, Yu Qin, Xiaochun Li

Cell Res. 2022 Feb; 32(2): 214–217. Published online 2021 Nov 9. doi: 10.1038/s41422-021-00585-8

PMCID:: PMC8807786

Article PDF–1.3M

Select item 877369713.

Structure and Function of the ABCD1 Variant Database: 20 Years, 940 Pathogenic Variants, and 3400 Cases of Adrenoleukodystrophy

Eric J. Mallack, Kerry Gao, Marc Engelen, Stephan Kemp

Cells. 2022 Jan; 11(2): 283. Published online 2022 Jan 14. doi: 10.3390/cells11020283

PMCID:: PMC8773697

Abstract Article PDF–2.5M

Select item 874887414.

Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment

Le Thi My Le, James Robert Thompson, Phuoc Xuan Dang, Janarjan Bhandari, Amer Alam

Commun Biol. 2022; 5: 7. Published online 2022 Jan 10. doi: 10.1038/s42003-021-02970-w

PMCID:: PMC8748874

Abstract Article PDF–5.4M

Select item 870135115.

Biochemical Studies in Fibroblasts to Interpret Variants of Unknown Significance in the ABCD1 Gene

Stephanie I. W. van de Stadt, Petra A. W. Mooyer, Inge M. E. Dijkstra, Conny J. M. Dekker, Divya Vats, Moin Vera, Maura R. Z. Ruzhnikov, Keith van Haren, Nelson Tang, Klaas Koop, Michel A. Willemsen, Joannie Hui, Frédéric M. Vaz, Merel S. Ebberink, Marc Engelen, Stephan Kemp, Sacha Ferdinandusse

Genes (Basel) 2021 Dec; 12(12): 1930. Published online 2021 Nov 30. doi: 10.3390/genes12121930

PMCID:: PMC8701351

Abstract Article PDF–1.1M

Select item 869991916.

Molecular Biomarkers for Adrenoleukodystrophy: An Unmet Need

Madison I. J. Honey, Yorrick R. J. Jaspers, Marc Engelen, Stephan Kemp, Irene C. Huffnagel

Cells. 2021 Dec; 10(12): 3427. Published online 2021 Dec 6. doi: 10.3390/cells10123427

PMCID:: PMC8699919

Abstract Article PDF–973K

Select item 824835617.

Evolution of adrenoleukodystrophy model systems

Roberto Montoro, Vivi M. Heine, Stephan Kemp, Marc Engelen

J Inherit Metab Dis. 2021 May; 44(3): 544–553. Published online 2021 Jan 7. doi: 10.1002/jimd.12357

PMCID:: PMC8248356

Abstract Article PDF–1.1M

Select item 820118118.

Peroxisomal ABC Transporters: An Update

Ali Tawbeh, Catherine Gondcaille, Doriane Trompier, Stéphane Savary

Int J Mol Sci. 2021 Jun; 22(11): 6093. Published online 2021 Jun 5. doi: 10.3390/ijms22116093

PMCID:: PMC8201181

Abstract Article PDF–1.9M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 816064520.

A Large Family with p.Arg554His Mutation in ABCD1: Clinical Features and Genotype/Phenotype Correlation in Female Carriers

Rosa Campopiano, Cinzia Femiano, Maria Antonietta Chiaravalloti, Rosangela Ferese, Diego Centonze, Fabio Buttari, Stefania Zampatti, Mirco Fanelli, Stefano Amatori, Carmelo D’Alessio, Emiliano Giardina, Francesco Fornai, Francesca Biagioni, Marianna Storto, Stefano Gambardella

Genes (Basel) 2021 May; 12(5): 775. Published online 2021 May 19. doi: 10.3390/genes12050775

PMCID:: PMC8160645

Abstract Article PDF–851K

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PMC Links for GEO Profiles (Select 34497390) (66)
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c-MYC depletion effect on carcinoma cell lines
c-MYC depletion effect on carcinoma cell lines
Accession: GDS2526

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Burn injury: liver metabolic and inflammatory response
Burn injury: liver metabolic and inflammatory response
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