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Select item 100339371.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 94423002.

Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis

Pengbo Yao, Taiqi Chen, Peng Jiang, Li Li, Wenjing Du

EMBO Rep. 2022 Sep; 23(9): e54391. Published online 2022 Jun 30. doi: 10.15252/embr.202154391

PMCID:: PMC9442300

Abstract Article PDF–5.2M

Select item 89418983.

N-Acetyltransferase 8 Promotes Viral Replication by Increasing the Stability of Enterovirus 71 Nonstructural Proteins

Xiaohui Zhao, Huijun Yuan, Hang Yang, Yan Liu, Meng Xun, Xiaozhen Li, Tingting Fan, Bo Wu, Shangrui Guo, Hongliang Wang

J Virol. 2022 Mar; 96(6): e00119-22. Prepublished online 2022 Feb 16. Published online 2022 Mar 23. doi: 10.1128/jvi.00119-22

Correction in:: J Virol. 2023 Mar; 97(3): e00257-23.

PMCID:: PMC8941898

Abstract Article PDF–4.3M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77926485.

NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD

Shengyuan Luo, Aditya Surapaneni, Zihe Zheng, Eugene P. Rhee, Josef Coresh, Adriana M. Hung, Girish N. Nadkarni, Bing Yu, Eric Boerwinkle, Adrienne Tin, Dan E. Arking, Inga Steinbrenner, Pascal Schlosser, Anna Köttgen, Morgan E. Grams

Clin J Am Soc Nephrol. 2021 Jan 7; 16(1): 37–47. Published online 2020 Dec 30. doi: 10.2215/CJN.08600520

PMCID:: PMC7792648

Abstract Article

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 48493577.

Role of Increased n-acetylaspartate Levels in Cancer

Behrouz Zand, Rebecca A. Previs, Niki M. Zacharias, Rajesha Rupaimoole, Takashi Mitamura, Archana Sidalaghatta Nagaraja, Michele Guindani, Heather J. Dalton, Lifeng Yang, Joelle Baddour, Abhinav Achreja, Wei Hu, Chad V. Pecot, Cristina Ivan, Sherry Y. Wu, Christopher R. McCullough, Kshipra M. Gharpure, Einav Shoshan, Sunila Pradeep, Lingegowda S. Mangala, Cristian Rodriguez-Aguayo, Ying Wang, Alpa M. Nick, Michael A. Davies, Guillermo Armaiz-Pena, Jinsong Liu, Susan K. Lutgendorf, Keith A. Baggerly, Menashe Bar Eli, Gabriel Lopez-Berestein, Deepak Nagrath, Pratip K. Bhattacharya, Anil K. Sood

J Natl Cancer Inst. 2016 Jun; 108(6): djv426. Published online 2016 Jan 26. doi: 10.1093/jnci/djv426

PMCID:: PMC4849357

Abstract Article PDF–12M

Select item 46496588.

Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint

Melanie L. Bailey, Tejomayee Singh, Patricia Mero, Jason Moffat, Philip Hieter

Genetics. 2015 Nov; 201(3): 885–895. Published online 2015 Sep 8. doi: 10.1534/genetics.115.180653

PMCID:: PMC4649658

Abstract Article PDF–1.8M

Select item 43172569.

Post-translational regulation of CD133 by ATase1/ATase2 mediated lysine acetylation

Anthony B. Mak, Mariana Pehar, Allison M.L. Nixon, Rashida A. Williams, Andrea C. Uetrecht, Luigi Puglielli, Jason Moffat

J Mol Biol. Author manuscript; available in PMC 2015 May 29.

Published in final edited form as: J Mol Biol. 2014 May 29; 426(11): 2175–2182. Published online 2014 Feb 17. doi: 10.1016/j.jmb.2014.02.012

PMCID:: PMC4317256

Abstract Article PDF–1.2M

Select item 423168110.

The Endoplasmic Reticulum-based Acetyltransferases, ATase1 and ATase2, Associate with the Oligosaccharyltransferase to Acetylate Correctly Folded Polypeptides

Yun Ding, Cosma D. Dellisanti, Mi Hee Ko, Cynthia Czajkowski, Luigi Puglielli

J Biol Chem. 2014 Nov 14; 289(46): 32044–32055. Published online 2014 Oct 9. doi: 10.1074/jbc.M114.585547

PMCID:: PMC4231681

Abstract Article PDF–2.5M

Select item 407910711.

Genome-Wide Association Study of a Heart Failure-Related Metabolomic Profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study

Bing Yu, Yan Zheng, Danny Alexander, Teri A. Manolio, Alvaro Alonso, Jennifer A. Nettleton, Eric Boerwinkle

Genet Epidemiol. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Genet Epidemiol. 2013 Dec; 37(8): 840–845. Published online 2013 Aug 11. doi: 10.1002/gepi.21752

PMCID:: PMC4079107

Abstract Article PDF–269K

Select item 406425412.

An atlas of genetic influences on human blood metabolites

So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo

Nat Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982

PMCID:: PMC4064254

Abstract Article PDF–2.4M

Select item 400459813.

Systematic identification of pathological lamin A interactors

Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli

Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733

PMCID:: PMC4004598

Abstract Article PDF–3.5M

Select item 395282614.

Genetic Determinants Influencing Human Serum Metabolome among African Americans

Bing Yu, Yan Zheng, Danny Alexander, Alanna C. Morrison, Josef Coresh, Eric Boerwinkle

PLoS Genet. 2014 Mar; 10(3): e1004212. Published online 2014 Mar 13. doi: 10.1371/journal.pgen.1004212

PMCID:: PMC3952826

Abstract Article PDF–794K

Select item 383283815.

Human metabolic individuality in biomedical and pharmaceutical research

Karsten Suhre, So-Youn Shin, Ann-Kristin Petersen, Robert P. Mohney, David Meredith, Brigitte Wägele, Elisabeth Altmaier, CARDIoGRAM, Panos Deloukas, Jeanette Erdmann, Elin Grundberg, Christopher J. Hammond, Martin Hrabé de Angelis, Gabi Kastenmüller, Anna Köttgen, Florian Kronenberg, Massimo Mangino, Christa Meisinger, Thomas Meitinger, Hans-Werner Mewes, Michael V. Milburn, Cornelia Prehn, Johannes Raffler, Janina S. Ried, Werner Römisch-Margl, Nilesh J. Samani, Kerrin S. Small, H.-Erich Wichmann, Guangju Zhai, Thomas Illig, Tim D. Spector, Jerzy Adamski, Nicole Soranzo, Christian Gieger

Nature. Author manuscript; available in PMC 2013 Nov 19.

Published in final edited form as: Nature. 2011 Aug 31; 477(7362): 10.1038/nature10354. Published online 2011 Aug 31. doi: 10.1038/nature10354

PMCID:: PMC3832838

Abstract Article PDF–839K

Select item 374858516.

Genetic loci influencing kidney function and chronic kidney disease in man

John C Chambers, Weihua Zhang, Graham M Lord, Pim van der Harst, Debbie A Lawlor, Joban S Sehmi, Daniel P Gale, Mark N Wass, Kourosh R Ahmadi, Stephan JL Bakker, Jacqui Beckmann, Henk JG Bilo, Murielle Bochud, Morris J Brown, Mark J Caulfield, John M C Connell, Terence Cook, Ioana Cotlarciuc, George Davey Smith, Ranil de Silva, Guohong Deng, Olivier Devuyst, Lambert D. Dikkeschei, Nada Dimkovic, Mark Dockrell, Anna Dominiczak, Shah Ebrahim, Thomas Eggermann, Martin Farrall, Luigi Ferrucci, Jurgen Floege, Nita G Forouhi, Ron T Gansevoort, Xijin Han, Bo Hedblad, Jaap J Homan van der Heide, Bouke G Hepkema, Maria Hernandez-Fuentes, Elina Hypponen, Toby Johnson, Paul E de Jong, Nanne Kleefstra, Vasiliki Lagou, Marta Lapsley, Yun Li, Ruth J F Loos, Jian'an Luan, Karin Luttropp, Céline Maréchal, Olle Melander, Patricia B Munroe, Louise Nordfors, Afshin Parsa, Brenda W. Penninx, Esperanza Perucha, Anneli Pouta, Inga Prokopenko, Paul J Roderick, Aimo Ruokonen, Nilesh Samani, Serena Sanna, Martin Schalling, David Schlessinger, Georg Schlieper, Marc AJ Seelen, Alan R Shuldiner, Marketa Sjögren, Johannes H. Smit, Harold Snieder, Nicole Soranzo, Timothy D Spector, Peter Stenvinkel, Michael JE Sternberg, Ramasamyiyer Swaminathan, Toshiko Tanaka, Lielith J. Ubink-Veltmaat, Manuela Uda, Peter Vollenweider, Chris Wallace, Dawn Waterworth, Klaus Zerres, Gerard Waeber, Nicholas J Wareham, Patrick H Maxwell, Mark I McCarthy, Marjo-Riitta Jarvelin, Vincent Mooser, Goncalo R Abecasis, Liz Lightstone, James Scott, Gerjan Navis, Paul Elliott, Jaspal S Kooner.

Nat Genet. Author manuscript; available in PMC 2013 Aug 21.

Published in final edited form as: Nat Genet. 2010 May; 42(5): 373–375. Published online 2010 Apr 11. doi: 10.1038/ng.566

PMCID:: PMC3748585

Abstract Article PDF–754K

Select item 371197017.

Using Multiple Measures for Quantitative Trait Association Analyses: Application to Estimated Glomerular Filtration Rate (eGFR)

A Tin, E Colantuoni, E Boerwinkle, A Kottgen, N Franceschini, BC Astor, J Coresh, WH Kao

J Hum Genet. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: J Hum Genet. 2013 Jul; 58(7): 461–466. Published online 2013 Mar 28. doi: 10.1038/jhg.2013.23

PMCID:: PMC3711970

Abstract Article PDF–297K

Select item 331869818.

Biochemical Inhibition of the Acetyltransferases ATase1 and ATase2 Reduces β-Secretase (BACE1) Levels and Aβ Generation

Yun Ding, Mi Hee Ko, Mariana Pehar, Frank Kotch, Noel R. Peters, Yun Luo, Shahriar M. Salamat, Luigi Puglielli

J Biol Chem. 2012 Mar 9; 287(11): 8424–8433. Published online 2012 Jan 20. doi: 10.1074/jbc.M111.310136

PMCID:: PMC3318698

Abstract Article PDF–2.5M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316952920.

A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection

George Nicholson, Mattias Rantalainen, Jia V. Li, Anthony D. Maher, Daniel Malmodin, Kourosh R. Ahmadi, Johan H. Faber, Amy Barrett, Josine L. Min, N. William Rayner, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc-Emmanuel Dumas, Ugis Sarkans, The MolPAGE Consortium, Peter Donnelly, Thomas Illig, Jerzy Adamski, Karsten Suhre, Maxine Allen, Krina T. Zondervan, Tim D. Spector, Jeremy K. Nicholson, John C. Lindon, Dorrit Baunsgaard, Elaine Holmes, Mark I. McCarthy, Chris C. Holmes

PLoS Genet. 2011 Sep; 7(9): e1002270. Published online 2011 Sep 8. doi: 10.1371/journal.pgen.1002270