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Select item 103330811.

DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma

Feng Xiao, Hong Zhu, Yun Guo, Zhe Zhang, Gufeng Sun, Kai Huang, Hua Guo, Guowen Hu

Aging (Albany NY) 2023 Jun 30; 15(12): 5673–5697. Published online 2023 Jun 29. doi: 10.18632/aging.204821

PMCID:: PMC10333081

Abstract Article PDF–4.8M

Select item 92528982.

MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma

Wenping Zhou, Yuanlin Xu, Jiuyang Zhang, Peipei Zhang, Zhihua Yao, Zheng Yan, Haiying Wang, Junfeng Chu, Shuna Yao, Shuang Zhao, Shujun Yang, Yongjun Guo, Jinxin Miao, Kangdong Liu, Wing C. Chan, Qingxin Xia, Yanyan Liu

Leukemia. 2022; 36(7): 1861–1869. Published online 2022 Apr 29. doi: 10.1038/s41375-022-01565-6

PMCID:: PMC9252898

Abstract Article PDF–2.9M

Select item 86175003.

De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

Anne-Perrine Foray, Sophie Candon, Sara Hildebrand, Cindy Marquet, Fabrice Valette, Coralie Pecquet, Sebastien Lemoine, Francina Langa-Vives, Michael Dumas, Peipei Hu, Pere Santamaria, Sylvaine You, Stephen Lyon, Lindsay Scott, Chun Hui Bu, Tao Wang, Darui Xu, Eva Marie Y. Moresco, Claudio Scazzocchio, Jean-François Bach, Bruce Beutler, Lucienne Chatenoud

Proc Natl Acad Sci U S A. 2021 Nov 23; 118(47): e2112032118. Published online 2021 Nov 15. doi: 10.1073/pnas.2112032118

PMCID:: PMC8617500

Abstract Article PDF–1.2M

Select item 83217014.

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP

Kanako Nishiyama, Masashi Maekawa, Tomoya Nakagita, Jun Nakayama, Takeshi Kiyoi, Mami Chosei, Akari Murakami, Yoshiaki Kamei, Hiroyuki Takeda, Yasutsugu Takada, Shigeki Higashiyama

Life Sci Alliance. 2021 Sep; 4(9): e202101095. Published online 2021 Jun 29. doi: 10.26508/lsa.202101095

PMCID:: PMC8321701

Abstract Article PDF–4.8M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75694886.

An allosteric site on MKP5 reveals a strategy for small molecule inhibition

Zachary T. K. Gannam, Kisuk Min, Shanelle R. Shillingford, Lei Zhang, James Herrington, Laura Abriola, Peter C. Gareiss, Georgios Pantouris, Argyrios Tzouvelekis, Naftali Kaminski, Xinbo Zhang, Jun Yu, Haya Jamali, Jonathan A. Ellman, Elias Lolis, Karen S. Anderson, Anton M. Bennett

Sci Signal. Author manuscript; available in PMC 2020 Oct 19.

Published in final edited form as: Sci Signal. 2020 Aug 25; 13(646): eaba3043. Published online 2020 Aug 25. doi: 10.1126/scisignal.aba3043

PMCID:: PMC7569488

Abstract Article PDF–3.1M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 68799008.

Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

Nikos Xylourgidis, Kisuk Min, Farida Ahangari, Guoying Yu, Jose D. Herazo-Maya, Theodoros Karampitsakos, Vassilis Aidinis, Leonhard Binzenhöfer, Demosthenes Bouros, Anton M. Bennett, Naftali Kaminski, Argyrios Tzouvelekis

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1; 317(5): L678–L689. Published online 2019 Sep 4. doi: 10.1152/ajplung.00264.2018

PMCID:: PMC6879900

Abstract Article

Select item 66919859.

Epigenome-wide effects of vitamin D on asthma bronchial epithelial cells

Nadia Boutaoui, Sandeep Puranik, Rong Zhang, Ting Wang, Daniel H. Hui, John Brehm, Erick Forno, Wei Chen, Juan C. Celedón

Epigenetics. 2019; 14(9): 844–849. Published online 2019 Jun 3. doi: 10.1080/15592294.2019.1622993

PMCID:: PMC6691985

Abstract Article PDF–1.9M

Select item 632192310.

DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling

Grace C. A. Manley, Clare A. Stokes, Elizabeth K. Marsh, Ian Sabroe, Lisa C. Parker

J Virol. 2019 Jan 15; 93(2): e01659-18. Prepublished online 2018 Oct 17. Published online 2019 Jan 4. doi: 10.1128/JVI.01659-18

PMCID:: PMC6321923

Abstract Article PDF–3.1M

Select item 603835211.

Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci

Monica Y. Sanchez-Contreras, Naomi Kouri, Casey N. Cook, Daniel J. Serie, Michael G. Heckman, NiCole A. Finch, Richard J. Caselli, Ryan J. Uitti, Zbigniew K. Wszolek, Neill Graff-Radford, Leonard Petrucelli, Li-San Wang, Gerard D. Schellenberg, Dennis W. Dickson, Rosa Rademakers, Owen A. Ross

Mol Neurodegener. 2018; 13: 37. Published online 2018 Jul 9. doi: 10.1186/s13024-018-0267-3

PMCID:: PMC6038352

Abstract Article PDF–1.2M

Select item 566346512.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 554841313.

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling

Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika

J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065

PMCID:: PMC5548413

Abstract Article PDF–5.2M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542315415.

AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10‐mediated regulatory pathway

Roman Hrstka, Pavla Bouchalova, Eva Michalova, Eva Matoulkova, Petr Muller, Philip J. Coates, Borivoj Vojtesek

Mol Oncol. 2016 May; 10(5): 652–662. Published online 2015 Dec 17. doi: 10.1016/j.molonc.2015.12.003

PMCID:: PMC5423154

Abstract Article PDF–1.2M

Select item 509860116.

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Richard S Houlston, Jeremy Cheadle, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Sarah L Spain, Peter Broderick, Enric Domingo, Susan Farrington, James GD Prendergast, Alan M Pittman, Evi Theodoratou, Christopher G Smith, Bianca Olver, Axel Walther, Rebecca A Barnetson, Michael Churchman, Emma EM Jaeger, Steven Penegar, Ella Barclay, Lynn Martin, Maggie Gorman, Rachel Mager, Elaine Johnstone, Rachel Midgley, Iina Niittymäki, Sari Tuupanen, James Colley, Shelley Idziaszczyk, The COGENT Consortium, Huw JM Thomas, Anneke M Lucassen, D Gareth R Evans, Eamonn R Maher, The CORGI Consortium, The COIN Collaborative Group, The COINB Collaborative Group, Timothy Maughan, Antigone Dimas, Emmanouil Dermitzakis, Jean-Baptiste Cazier, Lauri A Aaltonen, Paul Pharoah, David J Kerr, Luis G Carvajal-Carmona, Harry Campbell, Malcolm G Dunlop, Ian PM Tomlinson

Nat Genet. Author manuscript; available in PMC 2016 Nov 7.

Published in final edited form as: Nat Genet. 2010 Nov; 42(11): 973–977. Published online 2010 Oct 24. doi: 10.1038/ng.670

PMCID:: PMC5098601

Abstract Article PDF–1.0M

Select item 501331517.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Abstract Article PDF–3.2M

Select item 439629018.

Polymorphisms in the DUSP10 gene are associated with sex-specific colorectal cancer risk in a Han population

Xianglong Duan, Ya Gao, Hua Yang, Tian Feng, Tianbo Jin, Yanbin Long, Chao Chen

Int J Clin Exp Pathol. 2015; 8(2): 2018–2025. Published online 2015 Feb 1.

PMCID:: PMC4396290

Abstract Article PDF–476K

Select item 424987119.

Genetic Variants Associated with Serum Thyroid Stimulating Hormone (TSH) Levels in European Americans and African Americans from the eMERGE Network

Jennifer R. Malinowski, Joshua C. Denny, Suzette J. Bielinski, Melissa A. Basford, Yuki Bradford, Peggy L. Peissig, David Carrell, David R. Crosslin, Jyotishman Pathak, Luke Rasmussen, Jennifer Pacheco, Abel Kho, Katherine M. Newton, Rongling Li, Iftikhar J. Kullo, Christopher G. Chute, Rex L. Chisholm, Gail P. Jarvik, Eric B. Larson, Catherine A. McCarty, Daniel R. Masys, Dan M. Roden, Mariza de Andrade, Marylyn D. Ritchie, Dana C. Crawford

PLoS One. 2014; 9(12): e111301. Published online 2014 Dec 1. doi: 10.1371/journal.pone.0111301

PMCID:: PMC4249871

Abstract Article PDF–941K

Select item 406879720.

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

Ben Zhang, Wei-Hua Jia, Koichi Matsuda, Sun-Seog Kweon, Keitaro Matsuo, Yong-Bing Xiang, Aesun Shin, Sun Ha Jee, Dong-Hyun Kim, Qiuyin Cai, Jirong Long, Jiajun Shi, Wanqing Wen, Gong Yang, Yanfeng Zhang, Chun Li, Bingshan Li, Yan Guo, Zefang Ren, Bu-Tian Ji, Zhi-Zhong Pan, Atsushi Takahashi, Min-Ho Shin, Fumihiko Matsuda, Yu-Tang Gao, Jae Hwan Oh, Soriul Kim, Yoon-Ok Ahn, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Andrew T Chan, Jenny Chang-Claude, Martha L. Slattery, Colorectal Transdisciplinary (CORECT) Study, Stephen B. Gruber, Fredrick R. Schumacher, Stephanie L. Stenzel, Colon Cancer Family Registry (CCFR), Graham Casey, Hyeong-Rok Kim, Jin-Young Jeong, Ji Won Park, Hong-Lan Li, Satoyo Hosono, Sang-Hee Cho, Michiaki Kubo, Xiao-Ou Shu, Yi-Xin Zeng, Wei Zheng

Nat Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 533–542. Published online 2014 May 18. doi: 10.1038/ng.2985