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Select item 112912881.

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Anissa A. Widjaja, Wei-Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh K. Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L. George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A. Sims, Norbert Hübner, Enrico Petretto, Dominic J. Withers, Lena Ho, Jesus Gil, David Carling, Stuart A. Cook

Nature. 2024; 632(8023): 157–165. Published online 2024 Jul 17. doi: 10.1038/s41586-024-07701-9

PMCID:: PMC11291288

Abstract Article PDF–19M

Select item 112563672.

Geographical distribution of MTHFR C677T gene polymorphisms among the reproductive-age women in Chinese Han populations: based on migration

Yifen Shen, Yongchun Gu, Ying Tang, Hao Shen, Chao Liu

BMC Womens Health. 2024; 24: 407. Published online 2024 Jul 18. doi: 10.1186/s12905-024-03244-3

PMCID:: PMC11256367

Abstract Article PDF–2.6M

Select item 112432863.

Association of Maternal Dietary Habits and Infant MTHFR Gene Polymorphisms with Ventricular Septal Defect in Offspring: A Case–Control Study

Xiaorui Ruan, Ziye Li, Taowei Zhong, Ridan Lei, Manjun Luo, Mengting Sun, Jiabi Qin

Nutrients. 2024 Jul; 16(13): 2005. Published online 2024 Jun 24. doi: 10.3390/nu16132005

PMCID:: PMC11243286

Abstract Article PDF–1.7M

Select item 112292024.

Analysis of MTHFR C677T genotype and related factors in H-type hypertension in Tibet, China

Jiaojiao Yan, Yufei Zhang, Yaxi Zhou, Yang Wan, Hai Xiong

BMC Cardiovasc Disord. 2024; 24: 345. Published online 2024 Jul 8. doi: 10.1186/s12872-024-04015-6

PMCID:: PMC11229202

Abstract Article PDF–1.3M

Select item 112265865.

Aging is associated with impaired triggering of TRPV3-mediated cutaneous vasodilation: a crucial process for local heat exposure

Lisa S. Martin, Audrey Josset-Lamaugarny, Thomas El Jammal, Sylvie Ducreux, Fabien P. Chevalier, Bérengère Fromy

GeroScience. 2024 Aug; 46(4): 3567–3580. Published online 2023 Oct 19. doi: 10.1007/s11357-023-00981-5

PMCID:: PMC11226586

Abstract Article PDF–1.0M

Select item 112147776.

Balancing of mitochondrial translation through METTL8-mediated m³C modification of mitochondrial tRNAs

Eva Schöller, James Marks, Virginie Marchand, Astrid Bruckmann, Christopher A. Powell, Markus Reichold, Christian Daniel Mutti, Katja Dettmer, Regina Feederle, Stefan Hüttelmaier, Mark Helm, Peter Oefner, Michal Minczuk, Yuri Motorin, Markus Hafner, Gunter Meister

Mol Cell. Author manuscript; available in PMC 2024 Jun 30.

Published in final edited form as: Mol Cell. 2021 Dec 2; 81(23): 4810–4825.e12. Published online 2021 Nov 12. doi: 10.1016/j.molcel.2021.10.018

PMCID:: PMC11214777

Abstract Article PDF–2.7M

Select item 112144147.

ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase

Naga babu Chinnam, Roopa Thapar, Andrew S. Arvai, Altaf H. Sarker, Jennifer M. Soll, Tanmoy Paul, Aleem Syed, Daniel J. Rosenberg, Michal Hammel, Albino Bacolla, Panagiotis Katsonis, Abhishek Asthana, Miaw-Sheue Tsai, Ivaylo Ivanov, Olivier Lichtarge, Robert H. Silverman, Nima Mosammaparast, Susan E. Tsutakawa, John A. Tainer

J Biol Chem. 2024 Jun; 300(6): 107368. Published online 2024 May 14. doi: 10.1016/j.jbc.2024.107368

PMCID:: PMC11214414

Abstract Article PDF–6.7M

Select item 112038738.

Residence of the Nucleotide Sugar Transporter Family Members SLC35F1 and SLC35F6 in the Endosomal/Lysosomal Pathway

François Van den Bossche, Virginie Tevel, Florentine Gilis, Jean-François Gaussin, Marielle Boonen, Michel Jadot

Int J Mol Sci. 2024 Jun; 25(12): 6718. Published online 2024 Jun 18. doi: 10.3390/ijms25126718

PMCID:: PMC11203873

Abstract Article PDF–3.0M

Select item 111927429.

ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

Daniel J. Laverty, Shiv K. Gupta, Gary A. Bradshaw, Alexander S. Hunter, Brett L. Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N. Sarkaria, Zachary D. Nagel

Nat Commun. 2024; 15: 5294. Published online 2024 Jun 21. doi: 10.1038/s41467-024-49316-8

PMCID:: PMC11192742

Abstract Article PDF–2.8M

Select item 1118693210.

Association of Methylenetetrahydrofolate Reductase rs1801133 Gene Polymorphism with Cancer Risk and Septin 9 Methylation in Patients with Colorectal Cancer

Yafei Huang, Ting Su, Qiuting Duan, Xiangcong Wei, Xin Fan, Jinxiu Wan, Luping Liu, Ziqin Dian, Guiqian Zhang, Yi Sun, Tao Zhou, Ya Xu

J Gastrointest Cancer. 2024; 55(2): 778–786. Published online 2024 Jan 22. doi: 10.1007/s12029-024-01020-y

PMCID:: PMC11186932

Abstract Article PDF–1.3M

Select item 1118687111.

Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases

Pavel Dundr, Alba Machado-Lopez, Aymara Mas, Zuzana Věcková, Michal Mára, Adéla Richtárová, Radoslav Matěj, Ivana Stružinská, Michaela Kendall Bártů, Kristýna Němejcová, Jiří Dvořák, Jan Hojný

Virchows Arch. 2024; 484(6): 1015–1022. Published online 2023 Jul 19. doi: 10.1007/s00428-023-03603-9

PMCID:: PMC11186871

Abstract Article PDF–1.6M

Select item 1118017612.

Tripartite motif 8 promotes the progression of hepatocellular carcinoma via mediating ubiquitination of HNF1α

Yu Peng, Hui Qian, Wen-Ping Xu, Meng-Chao Xiao, Chen-Hong Ding, Fang Liu, Huan-Yu Hong, Shu-Qing Liu, Xin Zhang, Wei-Fen Xie

Cell Death Dis. 2024 Jun; 15(6): 416. Published online 2024 Jun 15. doi: 10.1038/s41419-024-06819-y

PMCID:: PMC11180176

Abstract Article PDF–5.0M

Select item 1117992013.

Identification of Prostaglandin I₂ Synthase Rare Variants in Patients With Williams Syndrome and Severe Peripheral Pulmonary Stenosis

Ayako Chida‐Nagai, Hiroyuki Akagawa, Saori Sawai, Yue‐Jiao Ma, Satoshi Yakuwa, Jun Muneuchi, Kazushi Yasuda, Hirokuni Yamazawa, Toshiyuki Yamamoto, Emi Takakuwa, Utano Tomaru, Yoshiyuki Furutani, Tatsuya Kato, Gen Harada, Kei Inai, Toshio Nakanishi, Atsushi Manabe, Atsuhito Takeda, Zhi‐Cheng Jing

J Am Heart Assoc. 2024 May 7; 13(9): e032872. Published online 2024 Apr 19. doi: 10.1161/JAHA.123.032872

PMCID:: PMC11179920

Abstract Article PDF–2.8M

Select item 1117180114.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 1116280615.

UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2

Lukas M Langer, Katharina Kurscheidt, Jérôme Basquin, Fabien Bonneau, Iuliia Iermak, Claire Basquin, Elena Conti

Nucleic Acids Res. 2024 Jun 10; 52(10): 6036–6048. Published online 2024 May 6. doi: 10.1093/nar/gkae323

PMCID:: PMC11162806

Abstract Article PDF–1.9M

Select item 1115984016.

Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer

Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park

Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x

PMCID:: PMC11159840

Abstract Article PDF–209K

Select item 1115981617.

Methylenetetrahydrofolate reductase polymorphisms, serum methylenetetrahydrofolate reductase levels, and risk of childhood acute lymphoblastic leukemia in a Chinese population

Na Tong, Yongjun Fang, Jie Li, Meilin Wang, Qin Lu, Shizhi Wang, Yuanyuan Tian, Liucheng Rong, Jielin Sun, Jianfeng Xu, Zhengdong Zhang

Cancer Sci. 2010 Mar; 101(3): 782–786. Published online 2009 Nov 11. doi: 10.1111/j.1349-7006.2009.01429.x

PMCID:: PMC11159816

Abstract Article PDF–176K

Select item 1115959318.

Genetic polymorphisms of methylenetetrahydrofolate reductase and aldehyde dehydrogenase 2, alcohol use and risk of colorectal adenomas: Self‐Defense Forces Health Study

Maho Hirose, Suminori Kono, Shinji Tabata, Shinsaku Ogawa, Keizo Yamaguchi, Masamichi Mineshita, Tomoko Hagiwara, Guang Yin, Kyong‐Yeon Lee, Akiko Tsuji, Noriaki Ikeda

Cancer Sci. 2005 Aug; 96(8): 513–518. Published online 2005 Aug 12. doi: 10.1111/j.1349-7006.2005.00077.x

PMCID:: PMC11159593

Abstract Article PDF–107K

Select item 1115939819.

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: The Fukuoka Colorectal Cancer Study

Guang Yin, Suminori Kono, Kengo Toyomura, Tomoko Hagiwara, Jun Nagano, Tetsuya Mizoue, Ryuichi Mibu, Masao Tanaka, Yoshihiro Kakeji, Yoshihiko Maehara, Takeshi Okamura, Koji Ikejiri, Kitaroh Futami, Yohichi Yasunami, Takafumi Maekawa, Kenji Takenaka, Hitoshi Ichimiya, Nobutoshi Imaizumi

Cancer Sci. 2004 Nov; 95(11): 908–913. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb02201.x

PMCID:: PMC11159398

Abstract Article PDF–155K

Select item 1115884020.

BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin

Hyun Jeong Shim, Joo Young Yun, Jun Eul Hwang, Woo Kyun Bae, Sang Hee Cho, Ji Hee Lee, Hee Nam Kim, Min Ho Shin, Sun Seog Kweon, Jae Hyuk Lee, Hyeoung Joon Kim, Ik Joo Chung

Cancer Sci. 2010 May; 101(5): 1247–1254. Published online 2010 Mar 12. doi: 10.1111/j.1349-7006.2010.01514.x

PMCID:: PMC11158840

Abstract Article PDF–215K

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PMC Links for GEO Profiles (Select 34884100) (4686)
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PMC Links for GEO Profiles (Select 86135453) (127)
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PMC Links for GEO Profiles (Select 77967234) (185)
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Genes, Immunoglobulin
Genes, Immunoglobulin
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light im...<br/>Year introduced: 1988

MeSH
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Ordered rearrangement of T-cell variable gene regions coding for the gamma-chain of antigen receptors.<br/>Year introduced: 1989

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