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Select item 101516151.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100729062.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 87286353.

Activin A receptor type 2A mutation affects the tumor biology of microsatellite instability-high gastric cancer

Kizuki Yuza, Masayuki Nagahashi, Hiroshi Ichikawa, Takaaki Hanyu, Masato Nakajima, Yoshifumi Shimada, Takashi Ishikawa, Jun Sakata, Shiho Takeuchi, Shujiro Okuda, Yasunobu Matsuda, Manabu Abe, Kenji Sakimura, Kazuaki Takabe, Toshifumi Wakai

J Gastrointest Surg. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: J Gastrointest Surg. 2021 Sep; 25(9): 2231–2241. Published online 2021 Jan 8. doi: 10.1007/s11605-020-04889-9

PMCID:: PMC8728635

Abstract Article PDF–1016K

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74273275.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 68826796.

Synovial chondromatosis and soft tissue chondroma: extra-osseous cartilaginous tumours defined by FN1 gene rearrangement

Fernanda Amary, Luis Perez-Casanova, Hongtao Ye, Lucia Cottone, Anna Strobl, Paul Cool, Elena Miranda, Fitim Berisha, William Aston, Maia Rocha, Paul O’Donnell, Nischalan Pillay, Roberto Tirabosco, Daniel Baumhoer, Edward S Hookway, Adrienne M Flanagan

Mod Pathol. Author manuscript; available in PMC 2019 Nov 28.

Published in final edited form as: Mod Pathol. 2019 Jun 14; 32(12): 1762–1771. Published online 2019 Jul 4. doi: 10.1038/s41379-019-0315-8

PMCID:: PMC6882679

Abstract Article PDF–1.6M

Select item 66817627.

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity

Erich J. Goebel, Richard A. Corpina, Cynthia S. Hinck, Magdalena Czepnik, Roselyne Castonguay, Rosa Grenha, Angela Boisvert, Gabriella Miklossy, Paul T. Fullerton, Martin M. Matzuk, Vincent J. Idone, Aris N. Economides, Ravindra Kumar, Andrew P. Hinck, Thomas B. Thompson

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15505–15513. Published online 2019 Jul 17. doi: 10.1073/pnas.1906253116

PMCID:: PMC6681762

Abstract Article PDF–1.8M

Select item 64117018.

The Activin Receptor, Activin-Like Kinase 4, Mediates Toxoplasma Gondii Activation of Hypoxia Inducible Factor-1

Agnieszka Lis, Mandi Wiley, Joan Vaughan, Peter C. Gray, Ira J. Blader

Front Cell Infect Microbiol. 2019; 9: 36. Published online 2019 Mar 5. doi: 10.3389/fcimb.2019.00036

PMCID:: PMC6411701

Abstract Article PDF–2.7M

Select item 63237059.

Non-additive effects of ACVR2A in preeclampsia in a Philippine population

Melissa D. Amosco, Gloria R. Tavera, Van Anthony M. Villar, Justin Michael A. Naniong, Lara Marie G. David-Bustamante, Scott M. Williams, Pedro A. Jose, Cynthia P. Palmes-Saloma

BMC Pregnancy Childbirth. 2019; 19: 11. Published online 2019 Jan 8. doi: 10.1186/s12884-018-2152-z

PMCID:: PMC6323705

Abstract Article PDF–703K

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535451411.

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Senem Aykul, Anthony Parenti, Kit Yee Chu, Jake Reske, Monique Floer, Amy Ralston, Erik Martinez-Hackert

J Biol Chem. 2017 Mar 10; 292(10): 4138–4151. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.747501

PMCID:: PMC5354514

Abstract Article PDF–3.1M

Select item 523361012.

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence

Lucy Cassar, Craig Nicholls, Alex R. Pinto, Ruping Chen, Lihui Wang, He Li, Jun-Ping Liu

Protein Cell. 2017 Jan; 8(1): 39–54. Published online 2016 Sep 30. doi: 10.1007/s13238-016-0322-1

PMCID:: PMC5233610

Abstract Article PDF–3.2M

Select item 510435613.

Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality

Alexander M. Kulminski, Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G. Arbeev, Elena Loiko, Liubov Arbeeva, Olivia Bagley, Matt Duan, Arseniy Yashkin, Fang Fang, Mikhail Kovtun, Svetlana V. Ukraintseva, Deqing Wu, Anatoliy I. Yashin

PLoS Genet. 2016 Nov; 12(11): e1006314. Published online 2016 Nov 10. doi: 10.1371/journal.pgen.1006314

PMCID:: PMC5104356

Abstract Article PDF–1.9M

Select item 475138314.

Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains

Yvonne Kienast, Ute Jucknischke, Stefan Scheiblich, Martina Thier, Mariana de Wouters, Alexander Haas, Christian Lehmann, Verena Brand, Dirk Bernicke, Konrad Honold, Stefan Lorenz

J Biol Chem. 2016 Feb 12; 291(7): 3395–3410. Published online 2015 Dec 16. doi: 10.1074/jbc.M115.680009

PMCID:: PMC4751383

Abstract Article PDF–4.0M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 446768116.

Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

Oddrun Elise Olsen, Karin Fahl Wader, Hanne Hella, Anne Kærsgaard Mylin, Ingemar Turesson, Ingerid Nesthus, Anders Waage, Anders Sundan, Toril Holien

Cell Commun Signal. 2015; 13: 27. Published online 2015 Jun 6. doi: 10.1186/s12964-015-0104-z

PMCID:: PMC4467681

Abstract Article PDF–1.3M

Select item 431900917.

Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation

Daniel Horbelt, Jan H. Boergermann, Apirat Chaikuad, Ivan Alfano, Eleanor Williams, Ilya Lukonin, Tobias Timmel, Alex N. Bullock, Petra Knaus

J Biol Chem. 2015 Feb 6; 290(6): 3390–3404. Published online 2014 Nov 3. doi: 10.1074/jbc.M114.604397

PMCID:: PMC4319009

Abstract Article PDF–3.5M

Select item 415549118.

Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers

Barbara Jung, E. Julieta Smith, Ryan T. Doctolero, Pascal Gervaz, Julio C. Alonso, Katsumi Miyai, Temitope Keku, Robert S. Sandler, John M. Carethers

Int J Cancer. Author manuscript; available in PMC 2014 Sep 5.

Published in final edited form as: Int J Cancer. 2006 May 15; 118(10): 2509–2513. doi: 10.1002/ijc.21710

PMCID:: PMC4155491

Abstract Article PDF–95K

Select item 415456219.

Activin Type 2 Receptor Restoration in MSI-H Colon Cancer Suppresses Growth and Enhances Migration With Activin

BARBARA H. JUNG, STAYCE E. BECK, JENNIFER CABRAL, EDDY CHAU, BETTY L. CABRERA, ANTONIO FIORINO, E. JULIETA SMITH, MELANIE BOCANEGRA, JOHN M. CARETHERS

Gastroenterology. Author manuscript; available in PMC 2014 Sep 4.

Published in final edited form as: Gastroenterology. 2007 Feb; 132(2): 633–644. Published online 2006 Nov 16. doi: 10.1053/j.gastro.2006.11.018

PMCID:: PMC4154562

Abstract Article PDF–865K

Select item 374253320.

Endoglin-Mediated Suppression of Prostate Cancer Invasion Is Regulated by Activin and Bone Morphogenetic Protein Type II Receptors

Michael J. Breen, Diarmuid M. Moran, Wenzhe Liu, Xiaoke Huang, Calvin P. H. Vary, Raymond C. Bergan

PLoS One. 2013; 8(8): e72407. Published online 2013 Aug 13. doi: 10.1371/journal.pone.0072407

PMCID:: PMC3742533

Abstract Article PDF–3.1M

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PMC Links for GEO Profiles (Select 34929571) (56)
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Serca2a effect on Dilated Cardiomyopathy iPSC-derived cardiomyocytes
Serca2a effect on Dilated Cardiomyopathy iPSC-derived cardiomyocytes
Accession: GDS4435

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Related DataSets for GEO Profiles (Select 89867033) (1)
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Related DataSets for GEO Profiles (Select 89867037) (1)
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Homo sapiens folylpoly-gamma-glutamate carboxypeptidase (FGCP) mRNA, complete cd...
Homo sapiens folylpoly-gamma-glutamate carboxypeptidase (FGCP) mRNA, complete cds
gi|5762481|gb|AF176574.1|

Nucleotide

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