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Select item 106646351.

The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome

Mutaz Amin, Claudia Gragnoli

J Ovarian Res. 2023; 16: 222. Published online 2023 Nov 22. doi: 10.1186/s13048-023-01280-5

PMCID:: PMC10664635

Abstract Article PDF–949K

Select item 102600202.

The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

Raul Araya-Secchi, Katrine Bugge, Pernille Seiffert, Amalie Petry, Gitte W Haxholm, Kresten Lindorff-Larsen, Stine Falsig Pedersen, Lise Arleth, Birthe B Kragelund

eLife. 2023; 12: e84645. Published online 2023 May 26. doi: 10.7554/eLife.84645

PMCID:: PMC10260020

Abstract Article PDF–6.9M

Select item 95200003.

Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness

Raghuveer Kavarthapu, Maria L. Dufau

Front Endocrinol (Lausanne) 2022; 13: 949396. Published online 2022 Sep 15. doi: 10.3389/fendo.2022.949396

PMCID:: PMC9520000

Abstract Article PDF–1.5M

Select item 94196914.

Breast Cancer and Prolactin – New Mechanisms and Models

Charles V Clevenger, Hallgeir Rui

Endocrinology. 2022 Oct; 163(10): bqac122. Published online 2022 Aug 4. doi: 10.1210/endocr/bqac122

PMCID:: PMC9419691

Abstract Article

Select item 79143415.

The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer

Huizhen Nie, Pei-Qi Huang, Shu-Heng Jiang, Qin Yang, Li-Peng Hu, Xiao-Mei Yang, Jun Li, Ya-Hui Wang, Qing Li, Yi-Fan Zhang, Lei Zhu, Yan-Li Zhang, Yanqiu Yu, Gary Guishan Xiao, Yong-Wei Sun, Jianguang Ji, Zhi-Gang Zhang

Theranostics. 2021; 11(8): 3898–3915. Published online 2021 Feb 6. doi: 10.7150/thno.51712

PMCID:: PMC7914341

Abstract Article PDF–4.7M

Select item 78035666.

Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Javier A. Menendez, Susan K. Peirce, Adriana Papadimitropoulou, Elisabet Cuyàs, Travis Vander Steen, Sara Verdura, Luciano Vellon, Wen Y. Chen, Ruth Lupu

Aging (Albany NY) 2020 Dec 31; 12(24): 24671–24692. Published online 2020 Dec 10. doi: 10.18632/aging.202289

PMCID:: PMC7803566

Abstract Article PDF–2.2M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71567178.

Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage

Dejene M. Tufa, Tyler Shank, Ashley M. Yingst, George Devon Trahan, Seonhui Shim, Jessica Lake, Renee Woods, Kenneth Jones, Michael R. Verneris

Sci Rep. 2020; 10: 6335. Published online 2020 Apr 14. doi: 10.1038/s41598-020-63346-4

PMCID:: PMC7156717

Abstract Article PDF–3.1M

Select item 64793509.

Concomitant Expression of Prolactin Receptor and TGFβ Receptors in Breast Cancer: Association with Less Aggressive Phenotype and Favorable Patient Outcome

Ibrahim Y. Hachim, Vanessa M. López-Ozuna, Mahmood Y. Hachim, Jean-Jacques Lebrun, Suhad Ali

Int J Mol Sci. 2019 Apr; 20(7): 1640. Published online 2019 Apr 2. doi: 10.3390/ijms20071640

PMCID:: PMC6479350

Abstract Article PDF–7.4M

Select item 640004910.

Association of prolactin receptor (PRLR) variants with prolactinomas

Caroline M Gorvin, Paul J Newey, Angela Rogers, Victoria Stokes, Matt J Neville, Kate E Lines, Georgia Ntali, Peter Lees, Patrick J Morrison, Panagiotis N Singhellakis, Fotini Ch Malandrinou, Niki Karavitaki, Ashley B Grossman, Fredrik Karpe, Rajesh V Thakker

Hum Mol Genet. 2019 Mar 15; 28(6): 1023–1037. Published online 2018 Nov 15. doi: 10.1093/hmg/ddy396

PMCID:: PMC6400049

Abstract Article PDF–10M

Select item 616668211.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 594382912.

The Role of Prolactin in Bone Metastasis and Breast Cancer Cell–Mediated Osteoclast Differentiation

Ashley Sutherland, Amanda Forsyth, Yingying Cong, Laurel Grant, Tzu-Hua Juan, Jae K. Lee, Alexander Klimowicz, Stephanie K. Petrillo, Jinghui Hu, Angela Chan, Florence Boutillon, Vincent Goffin, Cay Egan, Patricia A. Tang, Li Cai, Don Morris, Anthony Magliocco, Carrie S. Shemanko

J Natl Cancer Inst. 2016 Mar; 108(3): djv338. Published online 2015 Nov 19. doi: 10.1093/jnci/djv338

PMCID:: PMC5943829

Abstract Article PDF–24M

Select item 582692613.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 576294214.

The Prolactin Receptor Transactivation Domain Is Associated with Steroid Hormone Receptor Expression and Malignant Progression of Breast Cancer

Alyson A. Fiorillo, Terry R. Medler, Yvonne B. Feeney, Suzanne M. Wetz, Kalie L. Tommerdahl, Charles V. Clevenger

Am J Pathol. 2013 Jan; 182(1): 217–233. doi: 10.1016/j.ajpath.2012.09.021

PMCID:: PMC5762942

Abstract Article PDF–1.2M

Select item 541723415.

HMGN2 Inducibly Binds a Novel Transactivation Domain in Nuclear PRLr to Coordinate Stat5a-Mediated Transcription

Alyson A. Fiorillo, Terry R. Medler, Yvonne B. Feeney, Yi Liu, Kalie L. Tommerdahl, Charles V. Clevenger

Mol Endocrinol. September 1, 2011; 25(9): 1550–1564. Published online 2011 Aug 4. doi: 10.1210/me.2011-0106

PMCID:: PMC5417234

Abstract Article

Select item 534673616.

Stimulation of prolactin receptor induces STAT-5 phosphorylation and cellular invasion in glioblastoma multiforme

Amira Alkharusi, Shengze Yu, Natalia Landázuri, Fahad Zadjali, Belghis Davodi, Thomas Nyström, Torbjörn Gräslund, Afsar Rahbar, Gunnar Norstedt

Oncotarget. 2016 Nov 29; 7(48): 79572–79583. Published online 2016 Oct 24. doi: 10.18632/oncotarget.12840

PMCID:: PMC5346736

Abstract Article PDF–4.3M

Select item 496961217.

Prolactin Pro-Differentiation Pathway in Triple Negative Breast Cancer: Impact on Prognosis and Potential Therapy

Vanessa M. López-Ozuna, Ibrahim Y. Hachim, Mahmood Y. Hachim, Jean-Jacques Lebrun, Suhad Ali

Sci Rep. 2016; 6: 30934. Published online 2016 Aug 2. doi: 10.1038/srep30934

PMCID:: PMC4969612

Abstract Article PDF–4.0M

Select item 474886918.

Function of T_reg Cells Decreased in Patients With Systemic Lupus Erythematosus Due To the Effect of Prolactin

María Victoria Legorreta-Haquet, Karina Chávez-Rueda, Luis Chávez-Sánchez, Hernando Cervera-Castillo, Edgar Zenteno-Galindo, Leonor Barile-Fabris, Rubén Burgos-Vargas, Everardo Álvarez-Hernández, Francisco Blanco-Favela

Medicine (Baltimore) 2016 Feb; 95(5): e2384. Published online 2016 Feb 8. doi: 10.1097/MD.0000000000002384

PMCID:: PMC4748869

Abstract Article PDF–535K

Select item 464836119.

Zinc Binding to Human Lactogenic Hormones and the Human Prolactin Receptor

Jeffrey L. Voorhees, Geeta Rao, Timothy J. Gordon, Charles L. Brooks

FEBS Lett. Author manuscript; available in PMC 2015 Nov 17.

Published in final edited form as: FEBS Lett. 2011 Jun 23; 585(12): 1783–1788. Published online 2011 Apr 15. doi: 10.1016/j.febslet.2011.04.019

PMCID:: PMC4648361

Abstract Article PDF–835K

Select item 442432920.

A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling

Chi Zhang, Mads Nygaard, Gitte W. Haxholm, Florence Boutillon, Marie Bernadet, Sylviane Hoos, Patrick England, Isabelle Broutin, Birthe B. Kragelund, Vincent Goffin

J Biol Chem. 2015 May 8; 290(19): 11890–11904. Published online 2015 Mar 17. doi: 10.1074/jbc.M115.639096

PMCID:: PMC4424329

Abstract Article PDF–3.3M

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