PMC Links for GEO Profiles (Select 35379349) - PMC

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 99279414.

Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

Karl Bacos, Alexander Perfilyev, Alexandros Karagiannopoulos, Elaine Cowan, Jones K. Ofori, Ludivine Bertonnier-Brouty, Tina Rönn, Andreas Lindqvist, Cheng Luan, Sabrina Ruhrmann, Mtakai Ngara, Åsa Nilsson, Sevda Gheibi, Claire L. Lyons, Jens O. Lagerstedt, Mohammad Barghouth, Jonathan L.S. Esguerra, Petr Volkov, Malin Fex, Hindrik Mulder, Nils Wierup, Ulrika Krus, Isabella Artner, Lena Eliasson, Rashmi B. Prasad, Luis Rodrigo Cataldo, Charlotte Ling

J Clin Invest. 2023 Feb 15; 133(4): e163612. Published online 2023 Feb 15. doi: 10.1172/JCI163612

PMCID:: PMC9927941

Abstract Article PDF–3.0M

Select item 97501405.

PAX5 epigenetically orchestrates CD58 transcription and modulates blinatumomab response in acute lymphoblastic leukemia

Yizhen Li, Takaya Moriyama, Satoshi Yoshimura, Xujie Zhao, Zhenhua Li, Xu Yang, Elisabeth Paietta, Mark R. Litzow, Marina Konopleva, Jiyang Yu, Hiroto Inaba, Raul C. Ribeiro, Ching-Hon Pui, Jun J. Yang

Sci Adv. 2022 Dec; 8(50): eadd6403. Published online 2022 Dec 14. doi: 10.1126/sciadv.add6403

PMCID:: PMC9750140

Abstract Article PDF–1.6M

Select item 96242526.

DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus

Natália Birknerová, Helena Kovaříková, Ivana Baranová, Albína Přikrylová, Jan Laco, Hana Vošmiková, Barbora Gajdošová, Miroslav Hodek, Milan Vošmik, Vladimír Palička, Marcela Chmelařová

Epigenetics. 2022; 17(11): 1301–1310. Published online 2022 Jan 3. doi: 10.1080/15592294.2021.2018812

PMCID:: PMC9624252

Abstract Article PDF–1.4M

Select item 94450707.

The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa

Yubo Zhao, Jian Song, Weiwei Dong, Xiaobai Liu, Chunqing Yang, Di Wang, Yixue Xue, Xuelei Ruan, Libo Liu, Ping Wang, Mengyang Zhang, Yunhui Liu

Cell Death Dis. 2022 Sep; 13(9): 767. Published online 2022 Sep 5. doi: 10.1038/s41419-022-05219-4

PMCID:: PMC9445070

Abstract Article PDF–5.4M

Select item 91529988.

Distinct clinical characteristics of DUX4- and PAX5-altered childhood B-lymphoblastic leukemia

Zhenhua Li, Shawn Hsien Ren Lee, Winnie Hui Ni Chin, Yi Lu, Nan Jiang, Evelyn Huizi Lim, Elaine Coustan-Smith, Kean Hui Chiew, Bernice Ling Zhi Oh, Grace Shimin Koh, Zhiwei Chen, Shirley Kow Yin Kham, Thuan Chong Quah, Hai Peng Lin, Ah Moy Tan, Hany Ariffin, Jun J. Yang, Allen Eng-Juh Yeoh

Blood Adv. 2021 Dec 14; 5(23): 5226–5238. Published online 2021 Dec 7. doi: 10.1182/bloodadvances.2021004895

PMCID:: PMC9152998

Abstract Article PDF–3.9M

Select item 89603389.

Delineation of a novel neurodevelopmental syndrome associated with PAX5 haploinsufficiency

Yoel Gofin, Tianyun Wang, Madelyn A. Gillentine, Tiana M. Scott, Aliska M. Berry, Mahshid S. Azamian, Casie Genetti, Pankaj B. Agrawal, Jonathan Picker, Monica H. Wojcik, Mauricio R. Delgado, Sally Ann Lynch, Stephen W. Scherer, Jennifer L. Howe, Carlos A. Bacino, Stephanie DiTroia, Grace E. VanNoy, Anne O’Donnell-Luria, Seema R. Lalani, William D. Graf, Jill A. Rosenfeld, Evan E. Eichler, Rachel K. Earl, Daryl A. Scott

Hum Mutat. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Hum Mutat. 2022 Apr; 43(4): 461–470. Published online 2022 Jan 30. doi: 10.1002/humu.24332

PMCID:: PMC8960338

Abstract Article PDF–581K

Select item 892043110.

Paired box 5 increases the chemosensitivity of esophageal squamous cell cancer cells by promoting p53 signaling activity

Weiwei Zhang, Wenji Yan, Niansong Qian, Quanli Han, Weitao Zhang, Guanghai Dai

Chin Med J (Engl) 2022 Mar 5; 135(5): 606–618. Published online 2022 Feb 21. doi: 10.1097/CM9.0000000000002018

PMCID:: PMC8920431

Abstract Article PDF–1.6M

Select item 875073411.

Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing

Annie-Pier Beauregard, Brandon Hannay, Ehsan Gharib, Nicolas Crapoulet, Nicholas Finn, Roxann Guerrette, Amélie Ouellet, Gilles A. Robichaud

Cells. 2022 Jan; 11(1): 76. Published online 2021 Dec 28. doi: 10.3390/cells11010076

PMCID:: PMC8750734

Abstract Article PDF–4.1M

Select item 847602212.

Transcription factors Krüppel-like factor 4 and paired box 5 regulate the expression of the Grainyhead-like genes

Grzegorz Kotarba, Agnieszka Taracha-Wisniewska, Michal Miller, Michal Dabrowski, Tomasz Wilanowski

PLoS One. 2021; 16(9): e0257977. Published online 2021 Sep 27. doi: 10.1371/journal.pone.0257977

PMCID:: PMC8476022

Abstract Article PDF–2.3M

Select item 835296413.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 818510614.

Prognostic significance of p53, Sox11, and Pax5 co-expression in mantle cell lymphoma

Caixia Jing, Yuhuan Zheng, Yu Feng, Xia Cao, Caigang Xu

Sci Rep. 2021; 11: 11896. Published online 2021 Jun 7. doi: 10.1038/s41598-021-91433-7

PMCID:: PMC8185106

Abstract Article PDF–1.7M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808227616.

Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

Rebecca Harris, Suzanne Randle, Heike Laman

Biochem Biophys Res Commun. 2021 May 21; 554: 41–48. doi: 10.1016/j.bbrc.2021.03.052

PMCID:: PMC8082276

Abstract Article

Select item 790388717.

Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21)

Bénédicte Burlet, Selim Ramla, Cyril Fournier, Maria Jimena Abrey-Recalde, Camille Sauter, Marie-Lorraine Chrétien, Cédric Rossi, Yannis Duffourd, Sylviane Ragot, Céline Buriller, Benjamin Tournier, Caroline Chapusot, Nathalie Nadal, Jessica Racine, Julien Guy, François Bailly, Laurent Martin, Olivier Casasnovas, Jean-Noël Bastie, Denis Caillot, Juliette Albuisson, Cyril Broccardo, Catherine Thieblemont, Laurent Delva, Marc Maynadié, Romain Aucagne, Mary B. Callanan

Cold Spring Harb Mol Case Stud. 2021 Feb; 7(1): a005934. doi: 10.1101/mcs.a005934

PMCID:: PMC7903887

Abstract Article PDF–1.2M

Select item 789358818.

DGCR5 is activated by PAX5 and promotes pancreatic cancer via targeting miR-3163/TOP2A and activating Wnt/β-catenin pathway

Shi-lei Liu, Chen Cai, Zi-yi Yang, Zi-you Wu, Xiang-song Wu, Xue-feng Wang, Ping Dong, Wei Gong

Int J Biol Sci. 2021; 17(2): 498–513. Published online 2021 Jan 1. doi: 10.7150/ijbs.55636

PMCID:: PMC7893588

Abstract Article PDF–4.4M

Select item 781086519.

EBF1 drives hallmark B cell gene expression by enabling the interaction of PAX5 with the MLL H3K4 methyltransferase complex

Charles E. Bullerwell, Philippe Pierre Robichaud, Pierre M. L. Deprez, Andrew P. Joy, Gabriel Wajnberg, Darwin D’Souza, Simi Chacko, Sébastien Fournier, Nicolas Crapoulet, David A. Barnett, Stephen M. Lewis, Rodney J. Ouellette

Sci Rep. 2021; 11: 1537. Published online 2021 Jan 15. doi: 10.1038/s41598-021-81000-5

PMCID:: PMC7810865

Abstract Article PDF–2.0M

Select item 754039220.

Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP‐BFM acute lymphoblastic leukemia protocol

Mareike Jung, Maximilian Schieck, Winfried Hofmann, Marcel Tauscher, Jana Lentes, Anke Bergmann, Marie Stelter, Anja Möricke, Julia Alten, Brigitte Schlegelberger, Martin Schrappe, Martin Zimmermann, Martin Stanulla, Gunnar Cario, Doris Steinemann

Genes Chromosomes Cancer. 2020 Nov; 59(11): 667–671. Published online 2020 Jul 7. doi: 10.1002/gcc.22882

PMCID:: PMC7540392

Abstract Article PDF–865K

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