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Select item 107399861.

Expression of PVRL4, a molecular target for cancer treatment, is transcriptionally regulated by FOS

Tomoyuki Nanamiya, Kiyoko Takane, Kiyoshi Yamaguchi, Yuya Okawara, Mariko Arakawa, Akari Saku, Tsuneo Ikenoue, Tomoko Fujiyuki, Misako Yoneda, Chieko Kai, Yoichi Furukawa

Oncol Rep. 2024 Jan; 51(1): 17. Published online 2023 Dec 5. doi: 10.3892/or.2023.8676

PMCID:: PMC10739986

Abstract Article PDF–3.0M

Select item 107038722.

Nectin-4 regulates cellular senescence-associated enlargement of cell size

Ryoko Katasho, Taiki Nagano, Tetsushi Iwasaki, Shinji Kamada

Sci Rep. 2023; 13: 21602. Published online 2023 Dec 7. doi: 10.1038/s41598-023-48890-z

PMCID:: PMC10703872

Abstract Article PDF–2.6M

Select item 105672093.

A Recurrent Nonsense Mutation in NECTIN4 Underlying Ectodermal Dysplasia-Syndactyly Syndrome with a Novel Phenotype in a Consanguineous Kashmiri Family

Ghazanfar Ali, Sadia Sadia, Syeda Ain-ul- Batool, Zahid Azeem, Naheed Bashir Awan, Syed Akif Raza Kazmi, Zia- Ur- Rehman, Zeeshan Anjum, Fazal- Ur- Rehman, Abdul Wali, Kafaitullah Khan, Nasib Zaman, Muhammad Ayub, Muhammad Sajid, Noor Hassan

Genet Res (Camb) 2023; 2023: 9999660. Published online 2023 Oct 4. doi: 10.1155/2023/9999660

PMCID:: PMC10567209

Abstract Article PDF–1.3M

Select item 104045044.

A novel homozygous nonsense mutation in NECTIN4 gene in a Pakistani family with ectodermal dysplasia syndactyly syndrome 1

Bibi Hajra, Abdullah, Nousheen Bibi, Fibhaa Syed, Asmat Ullah, Wasim Ahmad, Umm-e-Kalsoom

An Bras Dermatol. 2023 Sep-Oct; 98(5): 580–586. Published online 2023 May 12. doi: 10.1016/j.abd.2022.07.009

PMCID:: PMC10404504

Abstract Article PDF–2.3M

Select item 100499955.

Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs’ development

Roberto Moretto, Marco Maria Germani, Mirella Giordano, Veronica Conca, Agnese Proietti, Cristina Niccoli, Filippo Pietrantonio, Sara Lonardi, Emiliano Tamburini, Alberto Zaniboni, Alessandro Passardi, Tiziana Pia Latiano, Valentina Fanotto, Samantha Di Donato, Michele Prisciandaro, Francesca Bergamo, Gianluca Masi, Gabriella Fontanini, Clara Ugolini, Chiara Cremolini

Br J Cancer. 2023 Mar 30; 128(7): 1391–1399. Published online 2023 Feb 9. doi: 10.1038/s41416-023-02180-7

PMCID:: PMC10049995

Abstract Article PDF–582K

Select item 97073346.

Nectin4 is a potential therapeutic target for asthma

Pureun-Haneul Lee, Seon Muk Choi, Min Hyeok An, Da Yeon Hwang, Shinhee Park, Ae Rin Baek, An-Soo Jang

Front Immunol. 2022; 13: 1049900. Published online 2022 Nov 15. doi: 10.3389/fimmu.2022.1049900

PMCID:: PMC9707334

Abstract Article PDF–9.8M

Select item 95844267.

Nectin-4 is widely expressed in head and neck squamous cell carcinoma

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart, Glen Kristiansen

Oncotarget. 2022; 13: 1166–1173. Published online 2022 Oct 20. doi: 10.18632/oncotarget.28299

PMCID:: PMC9584426

Abstract Article PDF–2.6M

Select item 92261038.

Heterogenous NECTIN4 expression in urothelial high-risk non-muscle-invasive bladder cancer

Stefan Garczyk, Stephan Degener, Felix Bischoff, Tician Schnitzler, Anne Salz, Reinhard Golz, Alexander Buchner, Gerald B. Schulz, Ursula Schneider, Nadine T. Gaisa, Ruth Knüchel

Virchows Arch. 2022; 481(1): 83–92. Published online 2022 Apr 28. doi: 10.1007/s00428-022-03328-1

PMCID:: PMC9226103

Abstract Article PDF–1.0M

Select item 89017549.

Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma

Yuka Tanaka, Maho Murata, Keiko Tanegashima, Yoshinao Oda, Takamichi Ito

Sci Rep. 2022; 12: 4031. Published online 2022 Mar 7. doi: 10.1038/s41598-022-07727-x

PMCID:: PMC8901754

Abstract Article PDF–9.6M

Select item 863482810.

Heterogeneity in NECTIN4 expression across molecular subtypes of urothelial cancer mediates sensitivity to enfortumab vedotin

Carissa E. Chu, Martin Sjöström, Emily A. Egusa, Ewan A. Gibb, Michelle L. Badura, Jun Zhu, Vadim S. Koshkin, Bradley A. Stohr, Maxwell V. Meng, Raj S. Pruthi, Terence W. Friedlander, Yair Lotan, Peter C. Black, Sima P. Porten, Felix Y. Feng, Jonathan Chou

Clin Cancer Res. Author manuscript; available in PMC 2022 Mar 15.

Published in final edited form as: Clin Cancer Res. 2021 Sep 15; 27(18): 5123–5130. Published online 2021 Jun 9. doi: 10.1158/1078-0432.CCR-20-4175

PMCID:: PMC8634828

Abstract Article PDF–1.0M

Select item 842905011.

Expression of Nectin-4 in Bladder Urothelial Carcinoma and in Morphologic Variants and Non-Urothelial Histotypes

Jean H. Hoffman-Censits, Kara A. Lombardo, Vamsi Parimi, Sonia Kamanda, Woonyoung Choi, Noah M. Hahn, David J. McConkey, Bridget M. McGuire, Trinity J. Bivalacqua, Max Kates, Andres Matoso

Appl Immunohistochem Mol Morphol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Appl Immunohistochem Mol Morphol. 2021 Sep 1; 29(8): 619–625. doi: 10.1097/PAI.0000000000000938

PMCID:: PMC8429050

Abstract Article PDF–3.4M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 801698613.

Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enhancing anchorage-independent T47D cell proliferation

Shin Kedashiro, Takeshi Kameyama, Kiyohito Mizutani, Yoshimi Takai

Sci Rep. 2021; 11: 7344. Published online 2021 Apr 1. doi: 10.1038/s41598-021-86437-2

PMCID:: PMC8016986

Abstract Article PDF–1.9M

Select item 783587514.

NECTIN4: A Novel Therapeutic Target for Melanoma

Yuka Tanaka, Maho Murata, Che-Hung Shen, Masutaka Furue, Takamichi Ito

Int J Mol Sci. 2021 Jan; 22(2): 976. Published online 2021 Jan 19. doi: 10.3390/ijms22020976

PMCID:: PMC7835875

Abstract Article PDF–3.2M

Select item 746066415.

NECTIN4 Expression in Extramammary Paget’s Disease: Implication of a New Therapeutic Target

Maho Murata, Takamichi Ito, Yuka Tanaka, Yumiko Kaku-Ito, Masutaka Furue

Int J Mol Sci. 2020 Aug; 21(16): 5891. Published online 2020 Aug 16. doi: 10.3390/ijms21165891

PMCID:: PMC7460664

Abstract Article PDF–1.7M

Select item 743281716.

Expression of Nectin-4 and PD-L1 in Upper Tract Urothelial Carcinoma

Eisuke Tomiyama, Kazutoshi Fujita, Maria Del Carmen Rodriguez Pena, Diana Taheri, Eri Banno, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Motohide Uemura, Tetsuya Takao, Seiji Yamaguchi, Hiroaki Fushimi, Kazuhiro Yoshimura, Hirotsugu Uemura, George J. Netto, Norio Nonomura

Int J Mol Sci. 2020 Aug; 21(15): 5390. Published online 2020 Jul 29. doi: 10.3390/ijms21155390

PMCID:: PMC7432817

Abstract Article PDF–1.6M

Select item 732206717.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 730266618.

Genetic variants in NECTIN4 encoding an adhesion molecule are associated with continued opioid use

Chiu-Ping Fang, Tung-Hsia Liu, Ren-Hua Chung, Hsiao-Hui Tsou, Hsiang-Wei Kuo, Sheng-Chang Wang, Chia-Chen Liu, Shu Chih Liu, Andrew C. H. Chen, Yu-Li Liu

PLoS One. 2020; 15(6): e0234549. Published online 2020 Jun 18. doi: 10.1371/journal.pone.0234549

PMCID:: PMC7302666

Abstract Article PDF–880K

Select item 727967019.

Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity

Adi Reches, Yael Ophir, Natan Stein, Inbal Kol, Batya Isaacson, Yoav Charpak Amikam, Afek Elnekave, Pinchas Tsukerman, Paola Kucan Brlic, Tihana Lenac, Barbara Seliger, Stipan Jonjic, Ofer Mandelboim

J Immunother Cancer. 2020; 8(1): e000266. Published online 2020 Jun 4. doi: 10.1136/jitc-2019-000266

PMCID:: PMC7279670

Abstract Article PDF–4.1M

Select item 716998320.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

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