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Items: 12

Select item 101723431.

Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells

Mie Kobayashi-Ishihara, Katarína Frazão Smutná, Florencia E. Alonso, Jordi Argilaguet, Anna Esteve-Codina, Kerstin Geiger, Meritxell Genescà, Judith Grau-Expósito, Clara Duran-Castells, Selina Rogenmoser, René Böttcher, Jennifer Jungfleisch, Baldomero Oliva, Javier P. Martinez, Manqing Li, Michael David, Makoto Yamagishi, Marta Ruiz-Riol, Christian Brander, Yasuko Tsunetsugu-Yokota, Maria J. Buzon, Juana Díez, Andreas Meyerhans

Commun Biol. 2023; 6: 487. Published online 2023 May 10. doi: 10.1038/s42003-023-04841-y

PMCID:: PMC10172343

Abstract Article PDF–3.5M

Select item 82854932.

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

Colin W. Garvie, Xiaoyun Wu, Malvina Papanastasiou, Sooncheol Lee, James Fuller, Gavin R. Schnitzler, Steven W. Horner, Andrew Baker, Terry Zhang, James P. Mullahoo, Lindsay Westlake, Stephanie H. Hoyt, Marcus Toetzl, Matthew J. Ranaghan, Luc de Waal, Joseph McGaunn, Bethany Kaplan, Federica Piccioni, Xiaoping Yang, Martin Lange, Adrian Tersteegen, Donald Raymond, Timothy A. Lewis, Steven A. Carr, Andrew D. Cherniack, Christopher T. Lemke, Matthew Meyerson, Heidi Greulich

Nat Commun. 2021; 12: 4375. Published online 2021 Jul 16. doi: 10.1038/s41467-021-24495-w

PMCID:: PMC8285493

Abstract Article PDF–3.8M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 70079824.

Schlafen12 Reduces the Aggressiveness of Triple Negative Breast Cancer through Post-Transcriptional Regulation of ZEB1 That Drives Stem Cell Differentiation

Sarmad Al-Marsoummi, Emilie Vomhof-DeKrey, Marc D. Basson

Cell Physiol Biochem. Author manuscript; available in PMC 2020 Feb 9.

Published in final edited form as: Cell Physiol Biochem. 2019; 53(6): 999–1014. doi: 10.33594/000000191

PMCID:: PMC7007982

Abstract Article PDF–1.9M

Select item 66577005.

Deciphering the Three-Domain Architecture in Schlafens and the Structures and Roles of Human Schlafen12 and SerpinB12 in Transcriptional Regulation

Jiaxing Chen, Leslie A. Kuhn

J Mol Graph Model. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Mol Graph Model. 2019 Jul; 90: 59–76. Published online 2019 Apr 9. doi: 10.1016/j.jmgm.2019.04.003

PMCID:: PMC6657700

Abstract Article PDF–2.8M

Select item 65710406.

Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells

Lakshmi S. Chaturvedi, Qinggang Wang, Shyam K. More, Emilie E. Vomhof-DeKrey, Marc D. Basson

Hum Cell. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Hum Cell. 2019 Jul; 32(3): 240–250. Published online 2019 Mar 14. doi: 10.1007/s13577-019-00247-3

PMCID:: PMC6571040

Abstract Article PDF–684K

Select item 61238217.

Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation

Marc D. Basson, Qinggang Wang, Lakshmi S. Chaturvedi, Shyam More, Emilie E. Vomhof-DeKrey, Sarmad Al-Marsoummi, Kelian Sun, Leslie A. Kuhn, Pavlo Kovalenko, Matti Kiupel

Cell Physiol Biochem. Author manuscript; available in PMC 2018 Sep 5.

Published in final edited form as: Cell Physiol Biochem. 2018; 48(3): 1274–1290. Published online 2018 Jul 25. doi: 10.1159/000492019

PMCID:: PMC6123821

Abstract Article PDF–918K

Select item 58269268.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366