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Select item 104975541.

Alk1 acts in non-endothelial VE-cadherin⁺ perineurial cells to maintain nerve branching during hair homeostasis

Gopal Chovatiya, Kefei Nina Li, Jonathan Li, Sangeeta Ghuwalewala, Tudorita Tumbar

Nat Commun. 2023; 14: 5623. Published online 2023 Sep 12. doi: 10.1038/s41467-023-40761-5

PMCID:: PMC10497554

Abstract Article PDF–17M

Select item 101838232.

Blood endothelial ALK1‐BMP4 signaling axis regulates adult hair follicle stem cell activation

Kefei Nina Li, Gopal Chovatiya, Daniel Youngjoo Ko, Sripad Sureshbabu, Tudorita Tumbar

EMBO J. 2023 May; 42(10): e112196. Published online 2023 Mar 30. doi: 10.15252/embj.2022112196

PMCID:: PMC10183823

Abstract Article PDF–20M

Select item 100269493.

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch

Hepatology. 2023 Apr; 77(4): 1211–1227. Published online 2022 Jul 17. doi: 10.1002/hep.32641

PMCID:: PMC10026949

Abstract Article PDF–3.8M

Select item 97604474.

N-glycosylation-mediated CD147 accumulation induces cardiac fibrosis in the diabetic heart through ALK5 activation

Mingchuan Liu, Tingwei Peng, Lang Hu, Min Wang, Dong Guo, Bingchao Qi, Gaotong Ren, Di Wang, Yunqing Li, Liqiang Song, Jianqiang Hu, Yan Li

Int J Biol Sci. 2023; 19(1): 137–155. Published online 2023 Jan 1. doi: 10.7150/ijbs.77469

PMCID:: PMC9760447

Abstract Article PDF–4.6M

Select item 96242625.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 92344966.

Endothelial Activin Receptor-Like Kinase 1 (ALK1) Regulates Myofibroblast Emergence and Peritubular Capillary Stability in the Early Stages of Kidney Fibrosis

Carlos Martínez-Salgado, Fernando Sánchez-Juanes, Francisco J. López-Hernández, José M. Muñoz-Félix

Front Pharmacol. 2022; 13: 843732. Published online 2022 Jun 13. doi: 10.3389/fphar.2022.843732

PMCID:: PMC9234496

Abstract Article PDF–4.5M

Select item 91607217.

Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling

Lowell T. Edgar, Hyojin Park, Jessica R. Crawshaw, James M. Osborne, Anne Eichmann, Miguel O. Bernabeu

Front Cell Dev Biol. 2022; 10: 840066. Published online 2022 May 19. doi: 10.3389/fcell.2022.840066

PMCID:: PMC9160721

Abstract Article PDF–4.6M

Select item 90213258.

Bone marrow derived Alk1 mutant endothelial cells and clonally expanded somatic Alk1 mutant endothelial cells contribute to the development of brain arteriovenous malformations in mice

Sonali S. Shaligram, Rui Zhang, Wan Zhu, Li Ma, Man Luo, Qiang Li, Miriam Weiss, Thomas Arnold, NG Santander Grez, Rich Liang, Leandro do Prado, Chaoliang Tang, Felix Pan, S. Paul Oh, Peipei Pan, Hua Su

Transl Stroke Res. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Transl Stroke Res. 2022 Jun; 13(3): 494–504. Published online 2021 Oct 21. doi: 10.1007/s12975-021-00955-9

PMCID:: PMC9021325

Abstract Article PDF–2.8M

Select item 90190549.

Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling

Guolun Wang, Bingqiang Wen, Zicheng Deng, Yufang Zhang, Olena A. Kolesnichenko, Vladimir Ustiyan, Arun Pradhan, Tanya V. Kalin, Vladimir V. Kalinichenko

Nat Commun. 2022; 13: 2080. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29746-y

PMCID:: PMC9019054

Abstract Article PDF–6.3M

Select item 880925210.

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Martin Guilliams, Johnny Bonnardel, Birthe Haest, Bart Vanderborght, Camille Wagner, Anneleen Remmerie, Anna Bujko, Liesbet Martens, Tinne Thoné, Robin Browaeys, Federico F. De Ponti, Bavo Vanneste, Christian Zwicker, Freya R. Svedberg, Tineke Vanhalewyn, Amanda Gonçalves, Saskia Lippens, Bert Devriendt, Eric Cox, Giuliano Ferrero, Valerie Wittamer, Andy Willaert, Suzanne J.F. Kaptein, Johan Neyts, Kai Dallmeier, Peter Geldhof, Stijn Casaert, Bart Deplancke, Peter ten Dijke, Anne Hoorens, Aude Vanlander, Frederik Berrevoet, Yves Van Nieuwenhove, Yvan Saeys, Wouter Saelens, Hans Van Vlierberghe, Lindsey Devisscher, Charlotte L. Scott

Cell. 2022 Jan 20; 185(2): 379–396.e38. doi: 10.1016/j.cell.2021.12.018

PMCID:: PMC8809252

Abstract Article

Select item 880333111.

ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection

Dianyuan Zhao, Fengjiao Yang, Yang Wang, Site Li, Yang Li, Fei Hou, Wenting Yang, Di Liu, Yuandong Tao, Qian Li, Jing Wang, Fuchu He, Li Tang

J Clin Invest. 2022 Feb 1; 132(3): e150489. Published online 2022 Feb 1. doi: 10.1172/JCI150489

PMCID:: PMC8803331

Abstract Article PDF–4.4M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 755413313.

Overexpression of Activin Receptor-Like Kinase 1 in Endothelial Cells Suppresses Development of Arteriovenous Malformations in Mouse Models Of Hereditary Hemorrhagic Telangiectasia

Yong Hwan Kim, Phuong-Nhung Vu, Se-woon Choe, Chang-Jin Jeon, Helen M. Arthur, Calvin P.H. Vary, Young Jae Lee, S. Paul Oh

Circ Res. Author manuscript; available in PMC 2021 Oct 9.

Published in final edited form as: Circ Res. 2020 Oct 9; 127(9): 1122–1137. Published online 2020 Jul 31. doi: 10.1161/CIRCRESAHA.119.316267

PMCID:: PMC7554133

Abstract Article PDF–2.1M

Select item 740373214.

Alk1 haploinsufficiency causes glomerular dysfunction and microalbuminuria in diabetic mice

Cindy Lora Gil, Nathalie Henley, François A. Leblond, Naoufal Akla, Louis-Philippe Laurin, Virginie Royal, Casimiro Gerarduzzi, Vincent Pichette, Bruno Larrivée

Sci Rep. 2020; 10: 13136. Published online 2020 Aug 4. doi: 10.1038/s41598-020-68515-z

PMCID:: PMC7403732

Abstract Article PDF–10M

Select item 704445315.

Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development

Edward Daniel, Haley R. Barlow, Gabrielle I. Sutton, Xiaowu Gu, Yadanar Htike, Mitzy A. Cowdin, Ondine Cleaver

Development. 2020 Feb 15; 147(4): dev181560. Published online 2020 Feb 20. doi: 10.1242/dev.181560

PMCID:: PMC7044453

Abstract Article

Select item 699412816.

Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models

Santiago Ruiz, Haitian Zhao, Pallavi Chandakkar, Julien Papoin, Hyunwoo Choi, Aya Nomura-Kitabayashi, Radhika Patel, Matthew Gillen, Li Diao, Prodyot K. Chatterjee, Mingzhu He, Yousef Al-Abed, Ping Wang, Christine N. Metz, S. Paul Oh, Lionel Blanc, Fabien Campagne, Philippe Marambaud

J Clin Invest. 2020 Feb 3; 130(2): 942–957. Published online 2020 Jan 21. doi: 10.1172/JCI127425

PMCID:: PMC6994128

Abstract Article PDF–28M

Select item 690844717.

The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension

Masato Morikawa, Yoshihide Mitani, Katarina Holmborn, Taichi Kato, Daizo Koinuma, Junko Maruyama, Eleftheria Vasilaki, Hirofumi Sawada, Mai Kobayashi, Takayuki Ozawa, Yasuyuki Morishita, Yasumasa Bessho, Shingo Maeda, Johan Ledin, Hiroyuki Aburatani, Ryoichiro Kageyama, Kazuo Maruyama, Carl-Henrik Heldin, Kohei Miyazono

Sci Signal. Author manuscript; available in PMC 2020 May 12.

Published in final edited form as: Sci Signal. 2019 Nov 12; 12(607): eaay4430. Published online 2019 Nov 12. doi: 10.1126/scisignal.aay4430