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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333682.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99305283.

SWR1 chromatin remodeling complex prevents mitotic slippage during spindle position checkpoint arrest

Ayse Koca Caydasi, Anton Khmelinskii, Zoulfia Darieva, Bahtiyar Kurtulmus, Michael Knop, Gislene Pereira

Mol Biol Cell. 2023 Feb 1; 34(2): ar11. Published online 2023 Jan 13. doi: 10.1091/mbc.E20-03-0179

PMCID:: PMC9930528

Abstract Article PDF–8.4M

Select item 96309864.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 85710636.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 77187517.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 68795588.

Mapping Ethanol Tolerance in Budding Yeast Reveals High Genetic Variation in a Wild Isolate

Roni Haas, Guy Horev, Ehud Lipkin, Inbar Kesten, Maya Portnoy, Keren Buhnik-Rosenblau, Morris Soller, Yechezkel Kashi

Front Genet. 2019; 10: 998. Published online 2019 Nov 20. doi: 10.3389/fgene.2019.00998

PMCID:: PMC6879558

Abstract Article PDF–2.2M

Select item 62162779.

A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export

Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, María E Pérez‐Martínez, Luis M Soares, Bernhard Dichtl, Stephen Buratowski, José E Pérez‐Ortín, Susana Rodríguez‐Navarro

EMBO Rep. 2018 Nov; 19(11): e45992. Published online 2018 Sep 24. doi: 10.15252/embr.201845992

PMCID:: PMC6216277

Abstract Article PDF–1.7M

Select item 621571310.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 611694911.

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

Sultan Ciftci-Yilmaz, Wei-Chun Au, Prashant K. Mishra, Jessica R. Eisenstatt, Joy Chang, Anthony R. Dawson, Iris Zhu, Mahfuzur Rahman, Sven Bilke, Michael Costanzo, Anastasia Baryshnikova, Chad L. Myers, Paul S. Meltzer, David Landsman, Richard E. Baker, Charles Boone, Munira A. Basrai

Genetics. 2018 Sep; 210(1): 203–218. Published online 2018 Jul 16. doi: 10.1534/genetics.118.301305

PMCID:: PMC6116949

Abstract Article PDF–2.1M

Select item 576535912.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 566188513.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 560025414.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 559580815.

Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment

Kristian Shulist, Eric Yen, Susanne Kaitna, Allen Leary, Alexandra Decterov, Debarun Gupta, Jackie Vogel

Sci Rep. 2017; 7: 11398. Published online 2017 Sep 12. doi: 10.1038/s41598-017-11789-7

Correction in:: Sci Rep. 2018; 8: 2513.

PMCID:: PMC5595808

Abstract Article PDF–5.9M

Select item 514238016.

Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae

Dimitris Kyriakou, Emmanouil Stavrou, Panayiota Demosthenous, Georgia Angelidou, Bryan-Joseph San Luis, Charles Boone, Vasilis J. Promponas, Antonis Kirmizis

BMC Biol. 2016; 14: 106. Published online 2016 Dec 7. doi: 10.1186/s12915-016-0325-7

PMCID:: PMC5142380

Abstract Article PDF–1.2M

Select item 505508317.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 504769318.

Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets

John J. Shin, Qurratulain Aftab, Pamela Austin, Jennifer A. McQueen, Tak Poon, Shu Chen Li, Barry P. Young, Calvin D. Roskelley, Christopher J. R. Loewen

Dis Model Mech. 2016 Sep 1; 9(9): 1039–1049. doi: 10.1242/dmm.023374

PMCID:: PMC5047693

Abstract Article

Select item 434224019.

Characterization of the Interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae

Gunjan Piya, Erica N. Mueller, Heather K. Haas, Padmaja L. Ghospurkar, Timothy M. Wilson, Jaime L. Jensen, Christopher L. Colbert, Stuart J. Haring

PLoS One. 2015; 10(2): e0116512. Published online 2015 Feb 26. doi: 10.1371/journal.pone.0116512

PMCID:: PMC4342240

Abstract Article PDF–2.0M

Select item 419673820.

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

Sujoy Lahiri, Jesse T. Chao, Shabnam Tavassoli, Andrew K. O. Wong, Vineet Choudhary, Barry P. Young, Christopher J. R. Loewen, William A. Prinz

PLoS Biol. 2014 Oct; 12(10): e1001969. Published online 2014 Oct 14. doi: 10.1371/journal.pbio.1001969

PMCID:: PMC4196738

Abstract Article PDF–8.0M

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