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Select item 93807131.

Blood D-Amino Acid Oxidase Levels Increased With Cognitive Decline Among People With Mild Cognitive Impairment: A Two-Year Prospective Study

Chieh-Hsin Lin, Hsien-Yuan Lane

Int J Neuropsychopharmacol. 2022 Aug; 25(8): 660–665. Published online 2022 Apr 17. doi: 10.1093/ijnp/pyac027

PMCID:: PMC9380713

Abstract Article PDF–246K

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75554903.

Mechanistic insights into the loss-of-function mechanisms of rare human D-amino acid oxidase variants implicated in amyotrophic lateral sclerosis

Aditya K. Padhi, Kam Y. J. Zhang

Sci Rep. 2020; 10: 17146. Published online 2020 Oct 13. doi: 10.1038/s41598-020-74048-2

PMCID:: PMC7555490

Abstract Article PDF–8.5M

Select item 75339234.

Human diamine oxidase is readily released from activated neutrophils ex vivo and in vivo but is rarely elevated in bacteremic patients

Thomas Boehm, Matthias Karer, Peter Matzneller, Nina Buchtele, Franz Ratzinger, Karin Petroczi, Christian Schoergenhofer, Michael Schwameis, Heinz Burgmann, Markus Zeitlinger, Bernd Jilma

Int J Immunopathol Pharmacol. 2020 Jan-Dec; 34: 2058738420954945. Published online 2020 Sep 30. doi: 10.1177/2058738420954945

PMCID:: PMC7533923

Abstract Article PDF–1.2M

Select item 75017425.

Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians

Paolo Piaggi, Çiğdem Köroğlu, Anup K Nair, Jeff Sutherland, Yunhua L Muller, Pankaj Kumar, Wen-Chi Hsueh, Sayuko Kobes, Alan R Shuldiner, Hye In Kim, Nehal Gosalia, Cristopher V Van Hout, Marcus Jones, William C Knowler, Jonathan Krakoff, Robert L Hanson, Clifton Bogardus, Leslie J Baier

J Clin Endocrinol Metab. 2020 Nov; 105(11): e3989–e4000. Published online 2020 Aug 20. doi: 10.1210/clinem/dgaa548

PMCID:: PMC7501742

Abstract Article

Select item 74635626.

Histamine Intolerance: The Current State of the Art

Oriol Comas-Basté, Sònia Sánchez-Pérez, Maria Teresa Veciana-Nogués, Mariluz Latorre-Moratalla, María del Carmen Vidal-Carou

Biomolecules. 2020 Aug; 10(8): 1181. Published online 2020 Aug 14. doi: 10.3390/biom10081181

PMCID:: PMC7463562

Abstract Article PDF–1.6M

Select item 68623237.

Substitution of Arginine 120 in Human D-Amino Acid Oxidase Favors FAD-Binding and Nuclear Mistargeting

Giulia Murtas, Silvia Sacchi, Loredano Pollegioni

Front Mol Biosci. 2019; 6: 125. Published online 2019 Nov 12. doi: 10.3389/fmolb.2019.00125

PMCID:: PMC6862323

Abstract Article PDF–1.0M

Select item 67426468.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 63392619.

d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species

Taiki Nagano, Shunsuke Yamao, Anju Terachi, Hidetora Yarimizu, Haruki Itoh, Ryoko Katasho, Kosuke Kawai, Akio Nakashima, Tetsushi Iwasaki, Ushio Kikkawa, Shinji Kamada

Life Sci Alliance. 2019 Feb; 2(1): e201800045. Published online 2019 Jan 18. doi: 10.26508/lsa.201800045

PMCID:: PMC6339261

Abstract Article PDF–2.3M

Select item 607772210.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 573711611.

Biochemical Properties of Human D-Amino Acid Oxidase

Giulia Murtas, Silvia Sacchi, Mattia Valentino, Loredano Pollegioni

Front Mol Biosci. 2017; 4: 88. Published online 2017 Dec 15. doi: 10.3389/fmolb.2017.00088

PMCID:: PMC5737116

Abstract Article PDF–1.5M

Select item 566593912.

Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging

Chieh-Hsin Lin, Hui-Ting Yang, Chih-Chiang Chiu, Hsien-Yuan Lane

Sci Rep. 2017; 7: 14849. Published online 2017 Nov 1. doi: 10.1038/s41598-017-13951-7

PMCID:: PMC5665939

Abstract Article PDF–1.2M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 488219014.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 479563715.

Haplotypes of the D-Amino Acid Oxidase Gene Are Significantly Associated with Schizophrenia and Its Neurocognitive Deficits

Yu-Li Liu, Sheng-Chang Wang, Hai-Gwo Hwu, Cathy Shen-Jang Fann, Ueng-Cheng Yang, Wei-Chih Yang, Pei-Chun Hsu, Chien-Ching Chang, Chun-Chiang Wen, Jyy-Jih Tsai-Wu, Tzung-Jeng Hwang, Ming H. Hsieh, Chen-Chung Liu, Yi-Ling Chien, Chiu-Ping Fang, Stephen V. Faraone, Ming T. Tsuang, Wei J. Chen, Chih-Min Liu

PLoS One. 2016; 11(3): e0150435. Published online 2016 Mar 17. doi: 10.1371/journal.pone.0150435

PMCID:: PMC4795637

Abstract Article PDF–356K

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 399653717.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 361074818.

The DAO Gene Is Associated with Schizophrenia and Interacts with Other Genes in the Taiwan Han Chinese Population

Hsin-Chou Yang, Chih-Min Liu, Yu-Li Liu, Chia-Wei Chen, Chien Ching Chang, Cathy S. J. Fann, Jen-Jie Chiou, Ueng-Cheng Yang, Chun-Houh Chen, Stephen V. Faraone, Ming T. Tsuang, Hai-Gwo Hwu

PLoS One. 2013; 8(3): e60099. Published online 2013 Mar 28. doi: 10.1371/journal.pone.0060099

PMCID:: PMC3610748

Abstract Article PDF–737K

Select item 359983219.

Schizophrenia susceptibility and NMDA-receptor mediated signalling: an association study involving 32 tagSNPs of DAO, DAOA, PPP3CC, and DTNBP1 genes

Emilio Sacchetti, Catia Scassellati, Alessandra Minelli, Paolo Valsecchi, Cristian Bonvicini, Patrizio Pasqualetti, Alessandro Galluzzo, Rosaria Pioli, Massimo Gennarelli

BMC Med Genet. 2013; 14: 33. Published online 2013 Mar 9. doi: 10.1186/1471-2350-14-33

PMCID:: PMC3599832

Abstract Article PDF–211K

Select item 349595320.

The Diamine Oxidase Gene Is Associated with Hypersensitivity Response to Non-Steroidal Anti-Inflammatory Drugs

José A. G. Agúndez, Pedro Ayuso, José A. Cornejo-García, Miguel Blanca, María J. Torres, Inmaculada Doña, María Salas, Natalia Blanca-López, Gabriela Canto, Carmen Rondon, Paloma Campo, José J. Laguna, Javier Fernández, Carmen Martínez, Elena García-Martín

PLoS One. 2012; 7(11): e47571. Published online 2012 Nov 12. doi: 10.1371/journal.pone.0047571

PMCID:: PMC3495953

Abstract Article PDF–191K

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